The Gary Null Show - 07.22.22

Antihypertensive and antioxidant activity in black beans

National Polytechnic Institute (Mexico)   16 July 2022 

 

Beans are one of the most important crops for the Mexican population due to its nutritional qualities. In fact, the country is one of the top 10 producers of this legume in the world, and several studies have reflected the correlation between consumption and decreased chronic degenerative diseases, cardiovascular diseases, obesity and diabetes.

 

Therefore, the National School of Biological Sciences of the National Polytechnic Institute (IPN-ENCB), conducted an investigation to evaluate the antioxidant and antihypertensive activity in black beans, and found that in addition to these qualities, proteins in the bean can remove heavy metals from the body. 

 

The polytechnic research identified bioactive peptides in the legume that have a beneficial effect as antihypertensive and antioxidant, which could favor the prevention and treatment of cardiovascular diseases, with a specific effect on blood pressure and oxidative stress. 

 

It was determined that fasolina and lectin hydrolysates (main proteins in the Jamapa black bean) had chelating activity (removal of heavy metals in the body) and, when hydrolyzed with pepsin-pancratin, they release peptides (amino acids) with antihypertensive and antioxidant effects. 

 

Could Eating Fruit More Often Keep Depression At Bay?

Aston University (UK), July 15, 2022

People who frequently eat fruit are more likely to report greater positive mental well-being and are less likely to report symptoms of depression than those who do not, according to new research from the College of Health and Life Sciences, Aston University

• The study found frequent fruit eaters had greater positive mental wellbeing
• The study surveyed 428 adults and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks and their psychological health
• The more often people ate fruit, the lower they scored for depression and the higher for mental well-being.

Published in the British Journal of Nutrition, the study surveyed 428 adults from across the UK and looked at the relationship between their consumption of fruit, vegetables, sweet and savoury food snacks, and their psychological health.

People who frequently snacked on nutrient-poor savoury foods (such as crisps) were more likely to experience 'everyday mental lapses' (known as subjective cognitive failures) and report lower mental wellbeing. A greater number of lapses, was associated with higher reported symptoms of anxiety, stress and depression, and lower mental wellbeing scores.

 

 

 

Effect of Short-term Quercetin, Caloric Restriction in Late Life Effective to Counter Age-Related Oxidative Macromolecular Damage.

Pondicherry University (India), July 13, 2022

 

According to news from Pondicherry, India, research stated, "Aging is characterized by gradual accumulation of macromolecular damage leading to progressive loss of physiological function and increased susceptibility to diverse diseases. Effective anti-aging strategies involving caloric restriction or antioxidant supplementation are receiving growing attention to attenuate macromolecular damage in age associated pathology."

Research from Pondicherry University, "In the present study, we for the first time investigated the effect of quercetin, caloric restriction and combined treatment (caloric restriction with quercetin) on oxidative stress parameters, acetylcholinesterase and ATPases enzyme activities in the cerebral cortex of aged male Wistar rats. 

Our results demonstrate that combined treatment of caloric restriction and quercetin significantly improved the age associated decline in the activities of endogenous antioxidant enzymes [such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)] and glutathione (GSH), and nitric oxide (NO). 

According to the news reporters, the research concluded: "Finally, we conclude that combined treatment of caloric restriction and quercetin in late life is an effective anti-aging therapy to counteract the age related accumulation of oxidative macromolecular damage."

 

 

 

How Drinking Soda on a Hot Day Can Damage Kidneys, Leading to Diabetes, Heart Disease

University of Buffalo, July 18, 2022

• Research demonstrates the acute deleterious effects soda can have on your kidney function when used to quench your thirst during exertion on a hot day.
• Drinking soda causes dehydration and raises markers for kidney disease when consumed after performing manual labor or exercise in 95-degree Fahrenheit weather.
• When you exert yourself in a hot environment, your body regulates blood pressure and conserves water by reducing blood flow to your kidneys. A sudden and steep drop in blood flow through your kidneys can cause acute kidney injury due to the fact that it reduces the amount of oxygen being delivered to your kidneys.
• Your diet has an overriding influence over the health of your kidneys, with sugar and excess protein topping the list of food components known to cause problems when consumed regularly.
• The study, published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, found soda caused dehydration and raised markers for kidney disease when consumed after performing manual labor in 95-degree F. weather.

“The volunteers completed … a 30-minute treadmill workout followed by three different five-minute lifting, dexterity and sledgehammer swinging activities. After 45 minutes of exercise, the volunteers rested for 15 minutes … while drinking 16 ounces of either a high-fructose, caffeinated soft drink or water. After the break, they repeated the cycle three more times for a total of four hours. Before leaving the laboratory, the volunteers were given more of their assigned beverages to drink before consuming any further fluids. The volume was either 1 liter or a volume equal to 115% of their body weight lost through sweating if that amount was greater.”

When volunteers drank soda, 75% of them had elevated levels of creatinine in their blood, a marker for kidney injury. Only 8% of participants in the water trial had elevated creatinine. When drinking soda, volunteers also had:

• A lower glomerular filtration rate, another marker for kidney injury
• Higher uric acid levels
• Mild dehydration
• Higher levels of vasopressin, an antidiuretic hormone that raises blood pressure

 

 

 

Black Seed Oil Extract Causes Oral Cancer Cells To Self-Destruct

Institute of Biochemistry and Biotechnology (Taiwan), July 20, 2022 

 

 

A range of chemotherapeutic options for treating cancer are available, however many of the treatments are themselves associated with significant morbidity and mortality. Today many cancer sufferers search for alternatives to conventional chemotherapy.

Increasingly natural alternative options are becoming available, often with little or no side-effects and concrete science is proving the effects of many natural substances against cancer.

 

One substance which is increasingly making the headlines is thymoquinone, an active component of Nigella sativa or black seed oil. Scientists from the Institute of Biochemistry and Biotechnology, Taiwan, have found that this remarkable compound elicits cytotoxic effects on various squamous cancer cell lines through various mechanisms.  The study examined a highly malignant strain of squamous cell carcinoma, which was taken from various patients with oral cancer; this particular cancer type also causes many other cancers of the head and neck.

 

The cell lines were grown in a lab and treated with different concentrations of thymoquinone. The results showed that after just 24 hours of treatment there was a significant concentration-dependent cytotoxic effect on these cells. The study further examined why this was happening. Their findings are quite remarkable as they were able to demonstrate that thymoquinone was a potent inhibitor of oral cancer cell viability via two distinct anti-neoplastic mechanisms.

 

 

No bones about it: Cannabis may be used to treat fractures

Tel Aviv University researcher finds non-psychotropic compound in marijuana can help heal bone fissures

Tel Aviv University (Israel), July 19, 2022

A study published in the Journal of Bone and Mineral Research by Tel Aviv University and Hebrew University researchers explores another promising new medical application for marijuana. According to the research, the administration of the non-psychotropic component cannabinoid cannabidiol (CBD) significantly helps heal bone fractures. The study, conducted on rats with mid-femoral fractures, found that CBD -- even when isolated from tetrahydrocannabinol (THC), the major psychoactive component of cannabis -- markedly enhanced the healing process of the femora after just eight weeks.

Undeniable clinical potential

The same team, in earlier research, discovered that cannabinoid receptors within our bodies stimulated bone formation and inhibited bone loss. This paves the way for the future use of cannabinoid drugs to combat osteoporosis and other bone-related diseases.

"We found that CBD alone makes bones stronger during healing, enhancing the maturation of the collagenous matrix, which provides the basis for new mineralization of bone tissue," said Dr. Gabet. "After being treated with CBD, the healed bone will be harder to break in the future."

The researchers injected one group of rats with CBD alone and another with a combination of CBD and THC. After evaluating the administration of THC and CBD together in the rats, they found CBD alone provided the necessary therapeutic stimulus.

 

OCCUPY PEACE & FREEDOM RALLY INFO

Saturday, July 23 -- 2:00 pm

Kingston, NY (at the historical 4 corners -- Crown and John Streets)

Speakers:

Gerald Celente

Judge Andrew Napolitano

Gary Null

Scott Ritter

Phil Giraldi (former CIA official)

Live music, food and drink