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Researchers investigate cancer-fighing properties of mango
Texas A&M University
In addition to being one of the most important tropical fruits consumed worldwide, recent studies by researchers at the Institute for Obesity Research and Program Evaluation at Texas A&M University in College Station have shown that mangoes also may help prevent breast cancer. Talcott and others recently completed one in vitro study and one using mice to see if the polyphenols found in mango did, in fact, exhibit inflammation- and cancer-fighting properties. “There was already some research done showing that polyphenolic compounds, such as those found in the mango, have cancer-fighting properties,” Talcott said. “Those compounds appear to have antioxidant properties that may contribute to decrease oxidative stress, which can lead to the onset of chronic diseases such as cancer. In addition to that, polyphenolics have been shown to be anti-inflammatory.” Talcott said interest in mango has been increasing in recent years and experimental data has already shown bioactive compounds present in mangoes exert anti-inflammatory, anti-carcinogenic, antiviral and antibacterial properties. “Based on this premise, we extracted mango polyphenols and tested their effects in vitro, or separate from their normal biological context, on commercially obtained non-cancer and cancer breast cells,” she said. These results of the study indicate that the cell-killing effects of mango polyphenols are specific to cancer cells, where inflammation was reduced in both cancer and non-cancer cells, seemingly through the involvement of miRNA-21 – short microRNA molecules associated with cancer,” Talcott said. A second study by this research group using hairless mice showed mango polyphenols also suppressed cell proliferation in the breast cancer BT474 cell line and tumor growth in mice with human breast carcinoma cells transplanted into them.
Ginseng can treat and prevent influenza and RSV, researcher finds
Georgia State University
Ginseng can help treat and prevent influenza and respiratory syncytial virus (RSV), a respiratory virus that infects the lungs and breathing passages, according to research findings by a scientist in Georgia State University’s new Institute for Biomedical Sciences. In a recent issue of Nutrients and an upcoming publication of the International Journal of Molecular Medicine, Sang-Moo Kang reports the beneficial effects of ginseng, a well-known herbal medicine, on human health. He partnered with a university and research institutes in South Korea that wanted international collaborative projects to study if ginseng can be used to improve health and protect against disease because of the potential benefit in fighting these viruses. There are no vaccines available for RSV, which affects millions and is the leading cause of inflammatory bronchiolitis pneumonia and viral death in infants and in some elderly adults. In his study published in Nutrients, Kang investigated whether red ginseng extract has preventive effects on influenza A virus infection. He found that red ginseng extract improves the survival of human lung epithelial cells infected with influenza virus. Also, treatment with red ginseng extract reduced the expression of genes that cause inflammation.
New study illustrates that potato protein ingestion strongly increases muscle protein synthesis rates at rest and during recovery from exercise
Maastricht University, The Netherlands
Exercise enthusiasts have long presumed animal protein to be superior to plant-derived options for muscle protein synthesis due to its essential amino acid profile. While many plant proteins are deficient in one or more essential amino acids necessary for optimal muscle growth and repair, a new randomized controlled study published in Medicine & Science in Sports & Exercise shows that plant-derived proteins can still induce strong anabolic responses. Researchers at Maastricht University, The Netherlands, found that consuming 30 grams of potato-derived protein concentrate following resistance exercise strongly increased muscle protein synthesis rates to levels that did not differ from the response following the ingestion of an equivalent amount of milk protein concentrate. In general, plant-derived proteins are considered to have lesser anabolic properties, due to their lower digestibility and incomplete amino acid profile. The results show that ingestion of 30 g potato-derived protein will support muscle growth and repair at rest and during recovery from exercise.”
Antipsychotic medication during pregnancy does affect babies
Monash University (Australia)
A seven-year study of women who take antipsychotic medication while pregnant, proves it can affect babies. The observational study, published in the journal PLOS ONE, reveals that whilst most women gave birth to healthy babies, the use of mood stabilisers or higher doses of antipsychotics during pregnancy increased the need for special care after birth with 43 per cent of babies placed in a Special Care Nursery (SCN) or a Neonatal Intensive Care Unit (NICU), almost three times the national rate in Australia. As well as an increased likelihood of the need for intensive care, the world-first study shows antipsychotic drugs affects babies in other ways; 18 per cent were born prematurely, 37 per cent showed signs of respiratory distress and 15 per cent developed withdrawal symptoms.