The Gary Null Show - 07.19.22

Videos:

1. There was an unexpected 40% increase in 'all cause deaths' in 2021 (8:28)

2.Dr. Mike Yeadon: The Reason Why They Had to Use Genetic Vaccines

3. [PROOF] The Great Reset Is HAPPENING!- Russell Brand

4. Dr. Peter McCullough, MD, MPH, Jun 27, 2022 Texas Senate HHS Testimony

5. If I Were the Devil: Paul Harvey (Clean Audio Version)

6. A few highlights of a recent speech of mine that went slightly viral - Simon O'Connor 

(Simon David O'Connor MP is a New Zealand politician and a member of the New Zealand House of Representatives. He is a member of the National Party. He has represented the Tāmaki electorate since 2011. He is a member of the Foreign Affairs, Defence, and Trade committee).

7. Gun Control and The Vaule Of Life

Health News:

• Cinnamon could stop Parkinson’s in its tracks 
  
• Leucine-rich protein supplements could benefit adults with sarcopenia 
  
• Nutrients for the bones
  
• Searching for meaning? Try appreciating the small things
  
• Want a higher GPA in college? Join a gym
  
• Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about

 

 

Cinnamon could stop Parkinson’s in its tracks 

Rush University Medical Center, July 14, 2022

In an article appearing in the Journal of Neuroimmune Pharmacology indicates that cinnamon could one day be used by Parkinson’s disease patients to prevent the disease from progressing.

Saurabh Khasnavis and Kalipada Pahan, PhD, of Rush University Medical Center studied the effects of the spice in a mouse model of Parkinson’s disease. They found that when cinnamon is metabolized into sodium benzoate in the blood and brain, the loss of beneficial proteins known as Parkin and DJ-1 is halted, while neurons that produce dopamine, a neurotransmitter that is reduced in Parkinson’s, are protected. Motor function, which can be significantly impaired by the disease, was improved in animals that received cinnamon.

"Cinnamon is metabolized in the liver to sodium benzoate, which is an FDA-approved drug used in the treatment for hepatic metabolic defects associated with hyperammonemia," explained lead researcher Dr Pahan

"Cinnamon has been used widely as a spice throughout the world for centuries,” he noted. “This could potentially be one of the safest approaches to halt disease progression in Parkinson's patients."

 

 

Leucine-rich protein supplements could benefit adults with sarcopenia

Seoul National University College of Medicine, July 15 2022. 

Sarcopenia is a condition characterized by muscle wasting that contributes to frailty in aging men and women. Results from a meta-analysis of randomized trials reported in the Archives of Gerontology and Geriatrics concluded that protein supplements rich in the essential branched-chain amino acid leucine could improve muscle strength in sarcopenic individuals.

“The treatment of choice for sarcopenia is still resistance exercise with nutritional supplementation because no pharmacological agents to treat sarcopenia have become available yet,” Sang Yoon Lee, MD, PhD, and colleagues at Seoul National University College of Medicine noted. 

The meta-analysis included 6 randomized, controlled trials that involved a total of 699 men and women with sarcopenia. Three hundred forty-six trial participants received a daily protein supplement containing 3 to 6 grams of leucine and 353 participants received a placebo or no leucine for 8 to 13 weeks. Muscle strength, muscle mass and physical performance were evaluated before and after the treatment periods.

Muscle strength significantly improved in leucine-supplemented participants as a primary outcome in comparison with the control groups. There was also a trend toward improvement in muscle mass and physical performance in the groups that received leucine. There was no significant difference in response between lower and higher amounts of leucine. No serious adverse events were reported.

 

 

Nutrients for the bones

Catalytic Longevity Foundation, July 13 2022. 

A review appearing in the International Journal of Molecular Sciences describes how specific nutrients activate bone-preserving mechanisms.

Osteoclasts are bone cells that break down bone tissue while osteoblasts synthesize bone. With respect to osteoblasts, the RUNX2 transcription factor is the master regulator of osteoblast formation and function, driving the transcription of a number of genes essential for the bone forming process.

Signaling pathways that drive RUNX2 gene transcription are triggered by bone morphogenetic proteins (BMP) 2 and 4. AMPK, which is activated by G. pentaphyllum, hesperidin and metformin, promotes BMP 2 and 4 expression in osteoblasts. 

The protein Sirt1 promotes RUNX2 activity. Sirt1 activation is increased by melatonin, nicotinamide riboside, glucosamine and thymoquinone, found in Nigella sativa. 

Activation of soluble guanylate cyclase (sGC), the only known nitric oxide receptor, also leads to the promotion of RUNX2. High doses of biotin activate sGC.

Nrf2 regulates the cells’ defense against oxidative stress, as well as enhancing the activation of RUNX2 in osteoblasts and osteocytes. Lipoic acid, melatonin, thymoquinone, astaxanthin and sulforaphane can promote Nrf2 activity. 

Activation of these mechanisms also promotes autophagy, a process in which the cells consume their own damaged cellular components, which helps to prevent apoptosis (programmed cell death) and senescence in osteoblasts and osteocytes.

“Regimens providing a selection of these nutraceuticals in clinically meaningful doses may have an important potential for preserving bone health,” the authors concluded. “Concurrent supplementation with taurine, N-acetylcysteine, vitamins D and K2, and minerals, including magnesium, zinc, and manganese, plus a diet naturally high in potassium, may also be helpful in this regard.”

 

 

 

Searching for meaning? Try appreciating the small things

Texas A&M University, July 18, 2022

Appreciating the intrinsic beauty in life's everyday moments can contribute to a more meaningful existence, according to new research.

In a paper recently published in Nature Human Behavior, Joshua Hicks, a professor in the Texas A&M University Department of Psychological and Brain Sciences, says this may be a previously unaccounted for factor tied to perceptions of meaning.

"It might not relate to whether you matter in the grand scheme of things, but we've shown people who value the little things, like your cup of coffee in the morning or being mindful in conversations with others, tend to have a high sense of meaning in life," he said.

Hicks studies existential psychology. Put simply, he aims to understand the "big questions" in life. He describes his main focus as the experience of life—studying people's subjective feeling that their life has meaning.

Scholars like Hicks generally agree there are three main sources of a subjectively meaningful existence: coherence, or the feeling that one's life "makes sense"; the possession of clear, long-term goals and sense of purpose; and existential mattering. This last factor, he says, is the belief that one's actions matter to others.

What Hicks and his co-authors argue in their latest research is that appreciating and finding value in experiences, referred to as experiential appreciation, is a fourth fundamental pathway toward finding meaning in life.

 

Want a higher GPA in college? Join a gym

Michigan State University, July 10, 2022

 

For those students looking to bump up their grade point averages during college, the answer may not be spending more time in a library or study hall, but in a gym.

 

New Michigan State University research shows that students who were members of the recreational sports and fitness centers on MSU's campus during their freshman and sophomore years had higher GPAs than those who weren't.

 

The research also indicated that students with memberships stayed in school longer. An increase of 3.5 percent in two-year retention rates was seen among this group.

 

The research supports previous theories suggesting that by creating an environment that connects students to an institution, in this case a university recreational facility, an increase in academic success and retention can occur. During the project, Pivarnik's team analyzed data from a sample of freshmen and sophomores, totaling 4,843 students, and compared the GPAs of those who purchased a fitness facility membership and those who did not. Results showed that after four consecutive semesters, the students with memberships obtained higher cumulative GPAs. They also had more credits completed by the end of their first year in college.

 

 

Men's hot flashes: Hypnotic relaxation may ease the discomfort men don't talk about

Baylor University, July 10, 2022

Men who experience hot flashes are unlikely to talk much about it, but they may find relief from their silent suffering if they are willing to try an unusual treatment, according to findings from a Baylor University case study.

After seven weeks of hypnotic relaxation therapy, a 69-year-old man who had uncontrolled hot flashes following prostate cancer surgery showed a drastic decrease not only in hot flashes but also an impressive improvement in sleep quality, according to the study.

Men's hot flashes are, of course, not related to estrogen, the primary female sex hormone. They occur in men with a history of prostate cancer — the second most common malignancy in men — or another disorder causing a testosterone deficiency.

Up to 80 percent of prostate survivors experience hot flashes, and about 50 percent of those experience them as severe and needing treatment. What's more, hot flashes due to prostate cancer tend to be more frequent, more severe and more prolonged than those women experience.

The new research follows previous published studies by Elkins that found a marked decrease in hot flashes among postmenopausal women and also among breast cancer survivors who have undergone hypnotic relaxation therapy. It reduced hot flashes by as much as 80 percent, and research findings by clinically trained therapists show it also improved participants' quality of life and lessened anxiety and depression. (Quality of life included such issues as work, sexuality, social and leisure activities, mood and concentration.)