The Gary Null Show

The Gary Null Show -10.19.22

Michael Hudson: China's Monetary System Challenges US Dollar Imperialism (0:44 - 8:44)
First 30 minuets of the Dr. James Thorp MD Interview (30:00)

The Gary Null Show - 10.18.22

Videos:
Ralph Schoellhammer: Elites Are Turning Against Their Own Civilization (23:43)
Bill Clinton and Blackrock team up to ACCELERATE the great reset | Redacted with Clayton Morris
Clare Daly Ireland pimped out like prostitutes for Obama (4:00)
Noam Chomsky – The Crimes of U.S. Presidents (11:00)
5.Ukraine Targets Elon Musk, US Aid Dwindles, Ukraine’s Offensive Increasingly Depleted (35:00)
 
Aronia berry supplementation supports gut, arterial healthKing’s College London, October 17 2022.
The issue of Clinical Nutrition reported findings from a randomized, double-blind, placebo-controlled trial that uncovered a benefit for supplementation with aronia berry among men and women with prehypertension.
“Aronia melanocarpa, or black chokeberry, has gained increased attention for its high content of (poly)phenols, and potential protection against chronic diseases such as cardiovascular disease and diabetes,” authors Melanie Le Sayec of King’s College London and colleagues remarked.
The trial included 102 participants between the ages of 40 and 70 years who received aronia berry extract capsules that contained 106 milligrams total polyphenols or identical placebo capsules for 12 weeks. Blood pressure, arterial function, gut microbiome composition and other factors were assessed before and after the treatment period.
At the end of the study, augmentation index and pulse wave velocity, which measure arterial stiffness, significantly improved among participants who received aronia in comparison with the placebo group. The aronia-supplemented group also had a significant increase in microbiome species richness and abundance of species that produce butyrate, a compound that has a favorable effect in gut health.
The researchers observed associations between plasma and urinary aronia-derived polyphenol metabolites, decreased arterial stiffness and various gut flora species. “To our knowledge, this is the first time these species are shown to correlate with beneficial effects on arterial function,” they announced.
“The present findings suggest that daily consumption of aronia berry extract led to improvements in arterial function in healthy middle-aged people, with a concomitant and related increase in potentially health-promoting bacterial taxa,” the authors concluded.
Zinc enhances albumin’s protective role against Parkinson’s diseaseUniversity of Science and Technology, October 17, 2022
Revealing zinc’s interaction with a critical transport protein underscores the need to study biological pathways under physiologically relevant conditions.
Heavy metals in the body have long been thought to induce the aggregation of disease-linked proteins, but a KAUST study shows this is not always the case.
It turns out that zinc ions tune the ability of human serum albumin (HSA), an abundant transport protein in the body, to better prevent α-synuclein from aggregating, a process directly linked to Parkinson’s disease.
In unrealistically massive quantities, zinc tends to accelerate the aggregation of α-synuclein, a neuronal protein implicated in Parkinson’s disease. This is what other scientists had shown in the past. But, under the types of biologically plausible experimental conditions considered by Al-Harthi, the metal actually interacts with HSA to cause the opposite effect.
Using a state-of-the-art imaging technique known as proton-less nuclear magnetic resonance spectroscopy, Al-Harthi and colleagues showed that zinc binding alters the chaperone function of HSA, a multifunctional molecule that plays a role in blocking α-synuclein accretion. In particular, zinc ions biased HSA toward stronger interactions with the aggregation-prone fragments of α-synuclein, a change that blunts fibril formation and slows down the toxic process of protein deposition that can lead to neurodegeneration.
High exposure to glyphosate in pregnancy could cause lower birth weights in babiesIndiana University School of Medicine, October 17, 2022
Indiana University School of Medicine researchers are learning more about the effects of herbicide exposure during pregnancy, finding glyphosate in 99% of the pregnant women they observed in the Midwest. In the study, published recently in Environmental Health, higher glyphosate levels were associated with lower birth weight and may also lead to higher neonatal intensive care unit admission risk.
This is the second study the researchers have conducted with significant findings. The team’s previous study, published in 2018, was the first study to confirm glyphosate in 93% of pregnancies which found associations with shortened pregnancies. Other recent studies have also confirmed their findings.
“Pesticide exposure in pregnancy, especially in early pregnancy, can imprint DNA and alter gene expression,” said Paul Winchester, MD, professor of clinical pediatrics and the study’s lead author.
Glyphosate is a chemical, commonly found in Roundup, used to kill weeds. It is used by farmers and homeowners across the United States, but especially in the Midwest on corn and soybeans. Previous studies have shown people can be exposed to glyphosate in all the foods they eat, even packaged or organic foods.
“As a neonatologist, I’m seeing more and more infants with problems like low birth weight as well as mothers with issues like obesity or gestational diabetes,” Winchester said. “We need to keep studying these herbicides long term to find out how they could be causing these issues and what we can do to prevent them.”
Omega-3 supplements linked to younger biological age in older peopleUniversity of South Australia & University of Newcastle, October 13, 2022Supplements of omega-3s may slow cellular ageing in older people with mild cognitive impairment, according to results of a pilot randomized clinical trial
DHA (docosahexaenoic acid) was associated with reduced shortening of telomeres, DNA sequences at the end of chromosomes that shorten as cells replicate and age, report researchers from Australia in Nutrition .
The aging and lifespan of normal, healthy cells are linked to the so-called telomerase shortening mechanism, which limits cells to a fixed number of divisions. During cell replication, the telomeres function by ensuring the cell’s chromosomes do not fuse with each other or rearrange, which can lead to cancer. Elizabeth Blackburn, a telomere pioneer at the University of California San Francisco, likened telomeres to the ends of shoelaces, without which the lace would unravel. With each replication the telomeres shorten, and when the telomeres are totally consumed, the cells are destroyed (apoptosis). Previous studies have also reported that telomeres are highly susceptible to oxidative stress.
This is not the first time that omega-3s have been linked to reduced telomere shortening, with findings from a study by researchers from the University of California, San Francisco indicating that high blood levels of omega-3 fatty acids may slow cellular ageing in people with coronary heart disease (JAMA, Vol. 303, pp. 250-257).
The new study, performed by scientists from the University of South Australia, and the University of Newcastle is an intervention study, albeit on a pilot scale.
Results of the study showed that the omega-6 group exhibited the greatest shortening of telomere length, compared to the DHA and EPA groups. Increased levels of DHA in red blood cells was significantly associated with reduced telomere shortening in the DHA group, said O’Callaghan and his co-workers.
Reading Is Good for Your Health
University of Stavanger (Norway) Oct. 8, 2022
People with poor reading skills are likely to be less healthy than those who read easily, according to recent research. Literacy skills are important for keeping in good shape. A relationship exists between self-perceived health and literacy, and draws on data from the international adult literacy and life skills survey (ALL).
Self-perceived health can mean feeling pains, physical condition hampering everyday activities, fatigue, or emotional problems which affect social relationships. “Other research shows that self-perceived health is closely related to actual well-being,” explains Lundetræ. “So adults with low literacy skills, as a group, are likely to be in worse physical shape than those who can read well.”
A perception of poor health increases among weak readers with age. It is greatest among those aged 45-65 and lowest in the youngest group, aged 16-24. “So it’s natural that the relationship between weak reading skills and the perception of poor health rises with age. That’s when you usually feel the effects of an unhealthy lifestyle or failing to look after yourself properly.”
“Advice on nutrition, healthy diet and physical activity is increasingly communicated through newspaper and magazine articles and on the internet,” Lundetræ explains. “We receive a great deal of information by reading. It’s conceivable that certain people miss out on important health advice because they read poorly and seldom.” How well people understand such written details could be crucial for how good they are at looking after their own health, Lundetræ observes. Health-related text is often complicated. It can contain a lot of technical terms, and is frequently badly written. That makes it difficult to grasp for poor readers.
A general improvement in reading skills might accordingly give more people better health and, in the longer terms, have a beneficial effect on the cost of health services. Since a lot of those who are most in need of such knowledge are poor readers, these texts have to be easy to read. They must be written in a language which is not too technical or which uses too many words, and must communicate clearly and simply.
Hair straightening chemicals associated with higher uterine cancer riskNational Institutes of Health, October 17, 2022
Women who used chemical hair straightening products were at higher risk for uterine cancer compared to women who did not report using these products, according to a new study from the National Institutes of Health. The researchers found no associations with uterine cancer for other hair products that the women reported using, including hair dyes, bleach, highlights, or perms.
The study data includes 33,497 U.S. women ages 35-74 participating in the Sister Study, a study led by the National Institute of Environmental Health Sciences (NIEHS), part of NIH, that seeks to identify risk factors for breast cancer and other health conditions. The women were followed for almost 11 years and during that time 378 uterine cancer cases were diagnosed.
The researchers found that women who reported frequent use of hair straightening products, defined as more than four times in the previous year, were more than twice as likely to go on to develop uterine cancer compared to those who did not use the products.
“We estimated that 1.64% of women who never used hair straighteners would go on to develop uterine cancer by the age of 70; but for frequent users, that risk goes up to 4.05%,” said Alexandra White, Ph.D., head of the NIEHS Environment and Cancer Epidemiology group and lead author on the new study. “This doubling rate is concerning. However, it is important to put this information into context—uterine cancer is a relatively rare type of cancer.”
Uterine cancer accounts for about 3% of all new cancer cases but is the most common cancer of the female reproductive system, with 65,950 estimated new cases in 2022. Studies show that incidence rates of uterine cancer have been rising in the United States, particularly among Black women.
The researchers did not collect information on brands or ingredients in the hair products the women used. However, in the paper they note that several chemicals that have been found in straighteners (such as parabens, bisphenol A, metals, and formaldehyde) could be contributing to the increased uterine cancer risk observed. Chemical exposure from hair product use, especially straighteners, could be more concerning than other personal care products due to increased absorption through the scalp which may be exacerbated by burns and lesions caused by straighteners.

The Gary Null Show - 10.17.22

Videos :
The world’s worst financial thief (10:30)
Oh No, something BIG is happening in Germany, the WEF is make it worse| Redacted with Clayton Morris (11:45)
Ukraine Targets Elon Musk, US Aid Dwindles, Ukraine’s Offensive Increasingly Depleted (35:00)
 
Research identifies the herbal supplements that are effective in treating anxiety
Global Neuroscience Initiative Foundation, October 6, 2022
A systematic review of research into the use of nutritional supplements for the treatment of anxiety disorders has found strong evidence for the use of extracts of passionflower or kava and combinations of L-lysine and L-arginine. Researchers writing in open access Nutrition Journal pooled the results of 24 studies involving a total of more than 2000 participants, showing that some nutritional and herbal supplements can be effective, without the risk of serious side effects.
The research was carried out by Shaheen Lakhan and Karen Vieira from the Global Neuroscience Initiative Foundation, a non-profit charity organization for the advancement of neurological and mental health patient welfare, education, and research, based in Los Angeles, USA. Lakhan said, “Our review and summary of the literature on herbal remedies and dietary supplements for anxiety should aid mental health practitioners in advising their patients and provide insight for future research in this field. We found mixed results – while passionflower or kava and L-lysine and L-arginine appeared to be effective, St John’s Wort and magnesium supplements were not”.
Of the studies included in the review, 21 were randomized controlled trials. Of these, 15 showed positive effects from either a nutritional or herbal remedy and any reported side effects were mild to moderate.
Melatonin improves mitochondrial function in rat model of diabetes
University of Granada, La Paz University Hospital & University of Texas,  October 6 2022. 
The Journal of Pineal Research published an article by researchers that reported a protective effect for melatonin on mitochondrial function in obese rats.
“Mitochondrial dysfunction in adipose tissue may contribute to obesity-related metabolic derangements such as type 2 diabetes mellitus,” write principle investigator Ahmad Agil and colleagues. “Because mitochondria are a target for melatonin action, the goal of this study was to investigate the effects of melatonin on mitochondrial function in white and beige inguinal adipose tissue of Zücker diabetic fatty rats.
The team divided eight diabetic rats and eight lean littermates to receive melatonin-enhanced or plain drinking water for six weeks, after which mitochondrial function was evaluated. They observed improvement in mitochondrial respiration, and a reduction in oxidative status among both lean and obese animals that received melatonin. 
He observed that, along with other factors, the rise in obesity in both developed and developing countries has coincided with exposure to artificial light at night, which inhibits the body’s production of melatonin.  The inhibition of melatonin production that occurs when a lamp, computer or television is left on leads to disrupted sleep and an increased risk of weight gain, which negatively impacts the mitochondria, promoting insulin resistance and diabetes. “For all these reasons, it is important to try to sleep in absolute darkness, to avoid interference in the generation of melatonin,” Professor Agil noted.
Walking can reduce breast cancer risk
American Cancer Society, October 4, 2022
Postmenopausal women who were very active or walked for at least seven hours a week had a reduced risk for breast cancer, according to a study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.
Women who engaged in at least an hour of vigorous physical activity every day had a 25 percent lower risk for breast cancer, and those who walked for at least seven hours a week had a 14 percent lower risk for breast cancer, in this study of 73,615 postmenopausal women.
“We examined whether recreational physical activity, specifically walking, was associated with lower breast cancer risk. Given that more than 60 percent of women report some daily walking, promoting walking as a healthy leisure-time activity could be an effective strategy for increasing physical activity among postmenopausal women,” said Alpa Patel, Ph.D., senior epidemiologist at the American Cancer Society (ACS) in Atlanta, G. “We were pleased to find that without any other recreational activity, just walking an average of one hour per day was associated with lower risk of breast cancer in these women.”
“Current guidelines recommend that adults should strive to get at least 2.5 hours per week of moderate-intensity activity, or 75 minutes per week of vigorous-intensity aerobic activity for overall health. Higher levels of activity may provide greater benefit for breast cancer prevention,” said Patel.
Patel and colleagues identified 73,615 postmenopausal women from a large cohort of 97,785 women aged 50 to 74 years.  All participants provided information on the average number of hours they spent on various physical activities including walking, jogging, swimming, playing tennis, bicycling, and performing aerobic exercises every week, and the number of hours spent in leisure time sitting, including watching television and reading. The researchers calculated the total hours of metabolic equivalent (MET) per week for each participant, which is a ratio of the energy spent during a specific activity to the resting metabolic rate.
The researchers found that about 9.2 percent of the participants did not partake in any physical activity, and about 47 percent of them reported walking as their only activity. The median MET expenditure among active women was 9.5 MET hours per week, which translates to 3.5 hours of moderately-paced walking.
They found that the most active women with 42 MET hours per week or more (at least one hour of vigorous activity every day) had a 25 percent lower risk for breast cancer compared with women who were least active, with less than seven MET hours per week (e.g., moderately-paced walking for two hours a week). Among women who reported walking as their only activity, those who walked for seven hours or more per week had a 14 percent lower risk for breast cancer, compared with those who walked for three hours or less. 
Selenium may help fight pre-cancer cervical condition
Arak University of Medical Sciences (Iran) , October 10, 2022
Long-term consumption of selenium supplements may help reverse the progression of the ‘pre-cancer’ condition cervical intraepithelial neoplasia grade 1 (CIN1), say researchers in Iran.
Published in the British Journal of Nutrition, the study saw 58 women diagnosed with this low-grade CIN given either a placebo tablet or 200 micrograms of selenium supplements as selenium yeast daily for six months.
After six months of supplementation they saw a regression in the condition and other beneficial metabolic effects.
This included significant decreases in fasting plasma glucose levels, serum insulin levels and serum TAG levels and increased HDL-cholesterol levels.
Cervical intra-epithelial neoplasia (CIN) is a term used to describe changes in the squamous cells of the cervix. CIN is not a cancer but if left untreated may develop into cancer and is therefore often described as a ‘pre-cancerous condition’ by doctors. However if left untreated, the risk of progression to invasive cervical carcinoma was about 30–50%.
The results from this latest research found significant rises in total plasma antioxidant capacity in the supplemented group compared with the placebo. There was also a significant decrease in malondialdehyde, a marker of oxidative stress. 
X-rays raise childhood leukemia risk
University of California at Berkeley, Oct 5, 2022
A new study by researchers at the University of California has revealed that diagnostic X-rays may increase the risk of developing childhood leukemia. 
Specifically, the researchers found that children with acute lymphoid leukemia (ALL) had almost twice the chance of having been exposed to three or more X-rays compared with children who did not have leukemia. 
For B-cell ALL, even one X-ray was enough to moderately increase the risk. 
The findings come from the Northern California Childhood Leukemia Study, a population-based case-control study that includes 35 counties in the northern and central regions of the state. 
The study included 827 children up to age 15 diagnosed with either ALL or AML. The children with leukemia were each compared with other children randomly selected from the California birth registry who were matched by factors such as age, gender, ethnicity and maternal race. 
The study found an increased risk from X-rays for ALL, but not for AML or T-cell leukemia, and there was no association with age at first exposure. 
Furthermore, there was no increased risk associated with prenatal exposure to X-rays or maternal X-rays occurring before pregnancy. 
Surfing can prevent suicidal feelings in combat veterans with PTSD
Loughborough University (UK) October 11, 2022 
Surfing can help improve well-being in combat veterans experiencing post-traumatic stress disorder and even avert suicidal feelings, according to a Loughborough University researcher. 
Nick Caddick said some of the veterans from Northern Ireland, Iraq and Afghanistan, who took part in his study, revealed that surfing had not only improved their health and quality of life but saved their lives. 
It is the first time research has been conducted into a ‘Blue Gym’ – the sea – therapy that is becoming increasingly popular in Britain and America and is being seen as an alternative to the traditional medical option which can involve drugs. 
It is estimated that 6.9 per cent of UK combat soldiers will go on to suffer significant distress as a result of their service.  Nick said: “A number of veterans said they would most likely not be around if it wasn’t for experiencing surfing in the ‘Blue Gym’ environment. For the men, being active in this environment was an excellent example of ‘exercise is medicine’ 
Nick spent time with them, both in and out of the water, observing how surfing gave them respite from PTSD symptoms like nightmares, flashbacks, severe depression, anxiety, and suicidal thoughts.  Nick stressed that surfing was not a cure, and that the veterans expected to live with PTSD for the rest of their lives.  But he said his research suggested that, if undertaken regularly, surfing was a powerful alternative to medical treatments which the veterans were sceptical about. 
“The veterans referred to it as a tremendous sense of freedom. It takes them completely away from the traumatic thoughts that spin through their minds all day long.   Most of them don’t believe they will be cured, but it gives them something important to look forward to, which stops them dwelling on all the bad stuff. 

The Gary Null Show - 10.14.22

VIDEOS:
CBDC infrastructure announced for America May 2023, first they need digital iD. Resist! (4:04)
I Confronted Congresswoman AOC On Her Support For Nuclear War and Ukrainian Nazis (2:03)
Tulsi Gabbard savages Democratic Party in exit announcement (1:00)
You’re Not Going To Believe This! | Mark Steyn & Eva Vlaardingerbroek – Dutch Farmers (8:45)
New Rule: A Unified Theory of Wokeness | Real Time with Bill Maher (HBO)
 
Folic Acid Supplement Linked With Reduction in Suicide Attempts and Self-HarmUniversity Of Chicago, October 10, 2022
Study finds folic acid treatment is associated with decreased risk of suicide attempt. The common, inexpensive supplement was linked with a 44% reduction in suicide attempts and self-harm.With nearly 46,000 people in America dying by suicide in 2020, it is one of the leading causes of death in the US. To decrease the risk of suicide, experts recommend many strategies and treatments including psychotherapy, economic support, peer support, and medications such as antidepressants. Few if any would be likely to put folic acid supplements on that list. However, an eye-opening study recent conducted at the University of Chicago may change that.
The study, published on in JAMA Psychiatry, used data from the health insurance claims of 866,586 patients. It investigated the relationship between folic acid treatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm). Robert Gibbons, PhD, the lead author of the study, is hopeful that these findings could improve suicide prevention efforts, especially because of how accessible folic acid is. He is the Blum-Riese Professor of Biostatistics and Medicine at the University of Chicago.
“There are no real side effects, it doesn’t cost a lot of money, you can get it without a prescription,” Gibbons said. “This could potentially save tens of thousands of lives.”
To investigate and further confirm the relationship between folic acid and suicide risk, Gibbons and his co-authors did this new study and focused specifically on folic acid, and accounted for many possible confounding factors, including age, sex, mental health diagnoses, other central nervous system drugs, conditions that affect folic acid metabolism, and more. Even after adjusting for all these factors, filling a prescription for folic acid was still associated with a decreased risk of attempting suicide.
They even found that the longer a person took folic acid, the lower their risk of suicide attempt tended to be. Each month of being prescribed folic acid was associated with an additional 5% decrease in risk of suicide attempt during the 24-month follow-up period of their study.
It also occurred to the authors that maybe people who take vitamin supplements, in general, want to improve their health and would thus be less likely to attempt suicide. To address this possibility, they did a similar analysis with another supplement, vitamin B12, as a negative control. But unlike folic acid, there didn’t seem to be any relationship between vitamin B12 and risk of suicide.
Zinc is cancer’s worst enemy: This mineral is key to preventing cancer, scientists concludeUniversity of Texas Arlington, October 3, 2022
Researchers from the University of Texas at Arlington have discovered the important role zinc can play in preventing cancer, especially the esophageal variety. Although past studies had indicated zinc had a protective effect on the esophagus when it comes to cancer, it wasn’t clear why.
A team of researchers led by Associate Professor of Nursing Zui Pan found that zinc has the incredibly useful ability to selectively stop the growth of cancerous cells while leaving normal esophageal epithelial cells intact. The researchers say their finding could help improve treatment for esophageal cancer and even provide some insight into how it might be prevented. Pan pointed out that many cancer patients have a zinc deficiency.
It’s a significant discovery; esophageal cancer is now the sixth-leading cause of cancer death in humans globally, and the average five-year survival rate for those with the disease is less than 20 percent.
Zinc deficiency is a serious problem. It’s needed for many of the proteins and enzymes in the body, and a lack of zinc can prevent cells from functioning properly, leading to the development of not only cancer but also other diseases. Zinc is also important for immune function and proper wound healing.
According to the National Institutes of Health (NIH), adult men need 11 milligrams per day, while women need 8 milligrams. It’s important not to go overboard, however; the NIH reports that zinc toxicity can cause adverse health effects, such as vomiting, diarrhea, headaches, and nausea.
Listen! Birdsong is good for mental healthMax Planck Institute for Human Development, October 13, 2022
When you next hear cheerful twittering of birds, you should stop and listen. Researchers from the Max Planck Institute for Human Development and the Universitätsklinikum Hamburg-Eppendorf (UKE) have shown that birdsong reduces anxiety and irrational thoughts. Their findings are published in the journal Scientific Reports.
In the study, the researchers examined how traffic noise and birdsong affect mood, paranoia, and cognitive functioning by carrying out a randomized online experiment with 295 participants. These individuals heard six minutes of either typical traffic noise or birdsong with varying numbers of different traffic sounds or birdsongs. Before and after hearing the sound clips, the participants filled in questionnaires assessing their mental health and performed cognitive tests.
The present study suggests that listening to birdsong reduces anxiety and paranoia in healthy participants. Birdsong did not appear to have an influence on depressive states in this experiment. Traffic noise, however, generally worsened depressive states, especially if the audio clip involved many different kinds of traffic sounds. The positive influence of birdsong on mood is already known, but to the best of the authors’ knowledge, this study is the first to reveal an effect on paranoid states. This was independent of whether the birdsong came from two or more different bird species. The researchers also found that neither birdsong nor traffic noise influenced cognitive performance.
In the researchers’ view, the explanation for these effects is that birdsong is a subtle indication of an intact natural environment, detracting attention from stressors that could otherwise signal an acute threat. Taken together, the results suggest interesting avenues for further research and applications, such as the active manipulation of background noise in different situations or the examination of its influence on patients with diagnosed anxiety disorders or paranoia.
Vegetable hormone helps reverse brain alterations caused by high-fat diets, obesityUniversity of Jaume I (Spain), October 8, 2022
The Neurobiotechnology research team of the Universitat Jaume I (UJI) in Castellón, Spain, headed by professor Ana María Sánchez, has proven the positive effects of a vegetable hormone, helping reverse brain alterations caused by high-fat diets, type-2 diabetes, obesity and physical inactivity.
“We have verified how a vegetable hormone, abscisic acid in green leafy plants, is able to counter the deleterious effects that a high-fat diet has on the central nervous system,” explains Ana María Sánchez. By making use of this molecule, expressed in plants, on an animal model with neuroinflammation induced by a high-fat diet, the results of the study “have shown that the alterations on the expression of some genes would be reversed, as well as alterations in the creation process of new neurons – neurogenesis -, while we also noted a decrease of the inflammation markers in the brain,” adds the UJI professor.
The study carried out in the UJI analyzed the expression of several genes related to the insulin signaling pathway together with the expression of genes which act as neuroinflammation markers with quantitative PCR. This way, as researcher Alberto Ribes Navarro argues, “we have been able to prove that the expression of proteins required for the proper functioning of insulin (the IRS) decreases in neuroinflammatory situations induced by a high-fat diet.” “With the addition of abscisic acid to the high-fat diet it is possible to recover the expression of these genes, even reaching normal levels”, he adds.
With a high-fat diet they noticed alterations to cognitive functions, which were also recovered with the vegetable hormone treatment.
Diets High in Processed Fiber May Increase Cancer RiskUniversity Of Toledo, October 13, 2022
The study found that men who had high processed fiber intake and high blood bile acid levels had a 40% higher risk of liver cancer.Fiber-enriched foods are often consumed by many individuals to promote weight loss and fend against chronic diseases like cancer and diabetes. Consuming highly refined fiber, however, may raise the risk of liver cancer in certain people, especially those with a silent vascular deformity, according to a recent study from The University of Toledo.
“We have worked for a long time on this idea that all diseases start from the gut,” said Dr. Matam Vijay-Kumar, a professor in the Department of Physiology and Pharmacology in the College of Medicine and Life Sciences and the paper’s senior author. “This study is a notable advancement of that concept. It also provides clues that may help identify individuals at a higher risk for liver cancer and potentially enable us to lower that risk with simple dietary modifications.”
Vijay-Kumar’s team published a major paper in the journal Cell in 2018 that revealed a large proportion of mice with immune system defects developed liver cancer after being given an inulin-fortified diet. Inulin is a refined, plant-based fermentable fiber that is sold in supermarkets as a health-promoting prebiotic. Additionally, it is often found in processed foods.The findings raised real questions about the potential risks of certain refined fibers, but only now do we understand why the mice were developing such aggressive cancer.”
The new study offers a clear explanation — and may have implications that go beyond laboratory animals.
As the team furthered its investigation, the researchers discovered all mice that developed malignant tumors had high concentrations of bile acids in their blood caused by a previously unnoticed congenital defect called a portosystemic shunt.While all mice with excess bile acids in their blood were predisposed to liver injury, only those fed inulin progressed to hepatocellular carcinoma, a deadly primary liver cancer.
Remarkably, 100% of the mice with high bile acids in their blood went on to develop cancer when fed inulin. None of the mice with low bile acids developed cancer when fed the same diet.
Dietary inulin is good in subduing inflammation, but it can be subverted into causing immunosuppression, which is not good for the liver.
Theorizing that high bile acid levels might serve as a viable marker for liver cancer risk, Vijay-Kumar’s team tested bile acid levels in serum samples collected between 1985 and 1988 as part of a large-scale cancer prevention study. The research team also sought to examine the relationship between fiber consumption, bile acid levels, and liver cancer in humans.
There are two basic types of naturally occurring dietary fiber, soluble and insoluble. Soluble fibers are fermented by gut bacteria into short-chain fatty acids. Insoluble fibers pass through the digestive system unchanged.
Intriguingly, researchers found high total fiber intake reduced the risk of liver cancer by 29% in those whose serum bile acid levels were in the lowest quartile of their sample.
However, in men whose blood bile acid levels placed them in the top quarter of the sample, high fiber intake conferred a 40% increased risk of liver cancer.
What kinds of exercise can boost long-term memory?
Georgia Institute of Technology October 5, 2022
Think that improving your memory is all brain training and omega-3 supplements? Think again. A study from researchers at Georgia Institute of Technology in Atlanta suggests that working out at the gym for as little as 20 minutes can improve long-term memory.
Previous studies have shown that memory may be improved by several months of aerobic exercises, such as running, cycling or swimming. However, the findings of the new study – published in the journal Acta Psychologica – demonstrate that a similar memory boost can be achieved in a much shorter period.
“Our study indicates that people don’t have to dedicate large amounts of time to give their brain a boost,” says Lisa Weinberg who led the project.
As well as looking at aerobic exercise, Weinberg’s team also examined how resistance exercise – weightlifting, push-ups and sit-ups – might affect memory.
The team recruited 46 participants (29 women and 17 men), who were randomly assigned into two groups. For the first part of the experiment, all participants viewed a series of 90 images on a computer screen. These images were split evenly been photographs that had been classed “positive,” “neutral,” and “negative.” These ranged from pictures of children playing on a waterslide, to photographs of clocks, to images of mutilated bodies. The participants were asked to try and remember as many of them as they could.
Next, the participants were randomized into “active” and “passive” groups and seated at leg extension resistance exercise machines. The active group were told to extend and contract each leg 50 times, at their personal maximum effort. The passive group were told to simply sit in the chair and allow the machine to move their legs.
Two days later, the participants were again shown the original 90 images they had seen previously, but this time they were mixed in with 90 new photos that the participants had not seen before.
The researchers found about 50% of the original photos were recalled by the passive group, while the active group remembered about 60% of the images. All of the participants were better at recalling the positive and negative images than the neutral images, but this was even more true for the active participants.

The Gary Null Show -10.13.22

Video:
No, this intensely aggressive AI isn’t fake (details in comment), w Elon Musk. (13:44)
PEOPLE FOR PEOPLE RADIO - DR ANA MIHALCEA MD PhD AND GUEST SASHA LATYPOVA 11TH SEPTEMBER 2022 
Neil Oliver - '...digital enslavement is coming...' 
New Rule: A Unified Theory of Wokeness | Real Time with Bill Maher (HBO)
 
Omega-3 fatty acid stops known trigger of lupus
Michigan State University, September 29, 2022 
 
A team of Michigan State University researchers has found that consuming an omega-3 fatty acid called DHA, or docosahexaenoic acid, can stop a known trigger of lupus and potentially other autoimmune disorders.
 
"What we discovered was when lupus was triggered by crystalline silica, a toxic mineral also known as quartz that's linked to human autoimmunity, DHA blocked the activation of the disease," said Melissa Bates, one of the study's lead authors in MSU's Department of Food Science and Human Nutrition and the Institute of Integrative Toxicology.
 
The preclinical study looked at the effect of DHA on lupus lesions in the lungs and kidneys of female mice that were already genetically predisposed to the disease. Their results were overwhelmingly positive.
 
"Ninety-six percent of the lung lesions were stopped with DHA after being triggered by the silica," said Jack Harkema, another study author and pulmonary pathologist. "I've never seen such a dramatic protective response in the lung before."
 
Lupus is considered a genetic disease and is triggered not only by inhaling crystalline silica toxicants, but also by other environmental factors such as sun exposure. Quartz is the most common, and most dangerous, form of crystalline silica and is often found in the agriculture, construction and mining industries where workers can breathe in the mineral dust. Lupus is the body's immune system attacking itself and it can damage any part of the body including skin, joints and organs.
 
Although it's still unknown exactly why DHA is able to prevent the onset of lupus, the researchers said this study provides scientists with a better model for looking at just how much DHA is needed to ward off the environmental trigger of the disease.
 
According to Harkema, the DHA could be changing the way cells, also known as macrophages, react to the silica in the lungs and somehow alter the immune system's response.
 
"What we do know is this study is a clear indication that eating DHA can prevent this one type of environmental triggering of lupus," Pestka said. "It can suppress many of the disease's signaling pathways, which current drugs on the market now try to target and treat."
 
 
Study offers real-world evidence of vitamin D’s protective effectsGerman Cancer Research Center, October 12 2022. 
A study reported in the Journal of Internal Medicine provides “real-world” evidence of the benefits of vitamin D supplementation. 
“Given the increasing importance of real-world evidence in determining the drug effectiveness outside of the strictly defined and controlled situations of randomized controlled trials, it is of great interest how the efficacy data of vitamin D3 supplementation obtained from well-defined and well-controlled clinical trial populations translate into effectiveness in real-world practice,” the authors remarked. “The primary objective of this study was to investigate whether the intake of vitamin D supplements (in the form of a vitamin D preparation or as part of a multivitamin product) is associated with reduced all-cause and cause-specific mortality including cancer mortality, cardiovascular disease mortality and respiratory disease mortality in the large UK Biobank, a nationwide, population-based cohort from the United Kingdom.”
The researchers analyzed information from 445,601 UK Biobank participants. Regular vitamin D supplement use was reported by 4.3% of the participants and multivitamin use was reported by 20.4%. 
Vitamin D and multivitamin supplement users had higher median 25-hydroxyvitamin D levels than nonusers. Multivitamin users experienced a 74% reduction in the risk of vitamin D deficiency and users of over-the-counter vitamin D supplements had an 84% lower risk.
During the 11.8-year median follow-up, individuals who used multivitamins had a 5% lower risk of mortality and those who used vitamin D had a 10% lower risk compared to nonusers. Regular vitamin D use was associated with 11% lower risk of dying from cancer and a 29% lower risk of mortality from respiratory disease. 
“This large study suggests that in the real world, the efficacy of vitamin D supplements in reducing mortality may be at least as good as observed in randomized clinical trials,” the authors concluded.
 
What you eat could contribute to your menstrual crampsNorth American Menopause Society, October 12, 2022
Despite the fact that menstrual pain (dysmenorrhea) is the leading cause of school absences for adolescent girls, few girls seek treatment. An analysis of relevant studies suggests that diet may be a key contributor, specifically diets high in meat, oil, sugar, salt, and coffee, which have been shown to cause inflammation. Results will be presented during The North American Menopause Society (NAMS) Annual Meeting in Atlanta.
Roughly 90% of adolescent girls experience menstrual pain. Most use over-the-counter medicine to manage the pain but with limited positive results. Evidence has highlighted that diets high in omega-3 fatty acids and low in processed foods, oil, and sugar reduce inflammation, a key contributor to menstrual pain.
This analysis was designed to study the effect of diet on menstrual pain and identify which foods contribute to it and which can reduce it. Research was conducted through a literature review that found multiple studies that examined dietary patterns that resulted in menstrual pain. In general terms, these studies found that diets high in omega-6 fatty acids promote inflammation and foods high in omega-3 fatty acids reduce it. The muscles in the uterus contract because of prostaglandins, which are active in inflammatory responses. When measuring the Dietary Inflammatory Index, it was found that those on a vegan diet (that excluded animal fat) had the lowest rates of inflammation.
“Researching the effects of diet on menstrual pain started as a search to remedy the pain I personally experienced; I wanted to understand the science behind the association. Learning about different foods that increase and decrease inflammation, which subsequently increase or reduce menstrual pain, revealed that diet is one of the many contributors to health outcomes that is often overlooked. I am hopeful that this research can help those who menstruate reduce the pain they experience and shed light on the importance of holistic treatment options,” says Serah Sannoh, lead author of the poster presentation from Rutgers University.
“Since menstrual pain is a leading cause of school absenteeism for adolescent girls, it’s important to explore options that can minimize the pain. Something like diet modification could be a relatively simple solution that could provide substantial relief for them,” said Dr. Stephanie Faubion, NAMS medical director.
 
Free radicals blamed for toxic buildup in Alzheimer’s brainsRutgers University, October 10, 2022. 
A study reported in Cell Death & Disease revealed a previously unknown mechanism that may contribute to traumatic brain injury and Alzheimer’s disease. While a buildup of the protein amyloid-beta has been hypothesized to be the major driver of Alzheimer’s disease, the study suggests that another protein, after undergoing oxidation by free radicals, could be a causative factor.
"Indeed, scientists have known for a long time that during aging or in neurodegenerative disease cells produce free radicals," explained lead researcher Federico Sesti, who is a professor of neuroscience and cell biology at Rutgers Robert Wood Johnson Medical School. "Free radicals are toxic molecules that can cause a reaction that results in lost electrons in important cellular components, including the channels."
Dr Sesti and colleagues determined that oxidation of a potassium channel known as KCNB1 results in a toxic buildup of this protein, leading to increased amyloid-beta production and damage to brain function. "The discovery of KCNB1's oxidation/build-up was found through observation of both mouse and human brains, which is significant as most scientific studies do not usually go beyond observing animals," Dr Sesti reported. "Further, KCBB1 channels may not only contribute to Alzheimer's but also to other conditions of stress as it was found in a recent study that they are formed following brain trauma."
 
 
How much radioactivity is in infant formula? 
University of Malaya & University of Surrey (UK), October 10, 2022
 
Based on measurements of radioactivity in samples of infant formula manufactured and sold around the world, researchers estimate that infants 1 year of age or younger who consume these formulas would ingest a significantly higher radioactivity dose than reported levels, but lower than internationally recommended limits. The researchers report the radioactivity levels for each brand of formula in an article published in Environmental Engineering Science, a peer-reviewed journal.
 
Onoshohwo Bemigho Uwatse and coauthors, University of Malaya (Kuala Lumpur, Malaysia), University of Surrey (U.K.), and King Saud University (Riyadh, Saudi Arabia), determined the levels of radioactive radium, potassium, radium, and thorium in 14 brands of powdered infant milk prepared and sold in various regions around the world. Levels of radioactivity in the formula may vary depending on several factors including radioactivity in the soil, grass, or hay from which the cows were fed, in other raw materials used in processing the formula, or due to processing conditions.
 
"This paper focuses on a topic that has not drawn significant attention but, nonetheless, has important health implications," says Domenico Grasso, PhD, Editor-in-Chief of Environmental Engineering Science and Provost, University of Delaware.
 
Using more social media increases depression risk for all personality types, study saysUniversity of Arkansas, October 11, 2022Public policy and education researchers found that higher social media exposure may contribute to depression, regardless of personality traits.In their recent study, high neuroticism was associated with an increased risk of developing depression within six months.On the other hand, low agreeableness was associated with a greater depression risk within that period.The study’s authors suggest that interventions should encourage reduced social media use for all personality types, especially high neuroticism, and low agreeableness.Experts have found evidence that suggests that increased social media use (SMU) may increase the risk of developing depression for certain personality characteristics, as the study showed that people low in conscientiousness with high SMU were more likely to perceive social isolation.
A new study led by University of Arkansas researchers further explores how personality traits may influence the development of SMU-related depression. The findings appear in the Journal of Affective Disorders Reports. 
Merrill and co-authors used data collected over six months by researchers, using a national sample of 978 people aged 18–30.  Merrill explained that her team used the Patient Health Questionnaire to assess depression at baseline and follow-up. The participants in this study reported how much time they spent on 10 leading social media platforms.
The researchers assessed personality traits. They examined data for associations between personality characteristics (neuroticism, agreeableness, openness, conscientiousness, and extraversion), social media use, and the development of depression over 6 months.
The team found that participants with high agreeableness were 49% less likely to develop depression than those with low agreeableness.However, individuals with high neuroticism were more than twice as likely to develop depression as people with low neuroticism.

The Gary Null Show - 10.12.22

Videos:
In COVID hearing, #Pfizer director admits: #vaccine was never tested on preventing transmission. (2:00)
Press conference after Pfizer CEO Albert Bourla refused to answer in front of European Parliament (24:52)
PEOPLE FOR PEOPLE RADIO – DR ANA MIHALCEA MD PhD AND GUEST SASHA LATYPOVA 11TH SEPTEMBER 2022 (Start @ 1:57 )
 
Component of citrus fruits found to block the formation of kidney cysts
University of London and Kingston University, UK October 3, 2022
A study published in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts.
Known as polycystic kidney disease, this is an inherited disorder which leads to the loss of kidney function, high blood pressure and the need for dialysis. Few treatment options are currently available.
The team of scientists from University of London and Kingston University London used a simple, single-celled amoeba to identify that naringenin regulates the PKD2 protein responsible for polycystic kidney disease and as a result, blocks formation of cysts.
To test how this discovery could apply in treatments, the team used a mammalian kidney cell-line, and triggered the formation of cysts in these cells. They were then able to block the formation of the cysts by adding naringenin and saw that when levels of the PKD2 protein were reduced in the kidney cells, so was the block in cyst formation, confirming that the effect was connected.
“Indeed, this study provides a good example of how chemicals identified in plants can help us develop new drugs for the treatment of disease,” added Professor Debbie Baines from St George’s, University of London.
Medical cannabis treats cancer and boosts the immune system, say scientists after reviewing more than 100 studiesRostock University Medical Center (Germany), October 1, 2022
A review of over 100 studies has shown that cannabis really is medicinal. Indeed, scientific analysis has shown that the cannabinoid compounds found in marijuana can stop cancer cells from dividing and spreading — and can even cut off blood supply to tumors. The researchers say that their findings prove that cannabis can be used as a cancer treatment. Does that mean plants will finally start getting recognized for their medicinal powers? One can only hope.
A team of German researchers, led by Professor Burkhard Hinz, have concluded that cannabis compounds can fight cancer. The scientists, say that an array of cannabinoids have medicinal value.
Professor Hinz and his team have shown that over 100 different studies have indicated cannabis has the ability to treat cancer.
“In this context accumulating data from preclinical models suggest that cannabinoids elicit anti-cancer effects on several levels of cancer progression,” Hinz explained.
“Clinical studies are now urgently needed to investigate the impact of cannabinoids on cancer growth and progression in patients,” he added.
Older adults living unhealthy lifestyles twice as likely to end up in a nursing homeOlder adults who lead an unhealthy lifestyle are twice as likely to end up needing a nursing home in comparison to their more active peers, a new study reveals.
Researchers at the University of Sydney found smoking, physical activity, sitting, and sleep quality to have a strong link to nursing home admission rates. Surprisingly, diet quality did not display the same connection.
Smokers were 55 percent more likely than non-smokers to end up needing nursing care. For the study, which is the first of its kind, researchers looked at data on more than 127,000 Australians who took part in a large study on healthy aging between 2006 and 2009. Study authors followed up with these patients for 11 years on average.
The team divided them into the three risk groups based on five lifestyle factors: smoking, physical activity, sitting, sleep quality, and diet quality.
One quarter of participants (24%) ended up in the lowest risk group with a score of nine or 10 points. Almost two-thirds (62%) were in the medium risk group with a score of six to eight points and 14 percent were in the unhealthiest group with a score below five points.
The Australian research team found people over 60 who eat badly and spend too much time on the sofa were 43 percent more likely to end up in a nursing home compared with the fittest retirees. Older people with a moderately healthy lifestyle were 12 percent more likely to need nursing home care than the healthiest seniors.
Paternal stress associated with children’s emotional and behavioral problems at age twoKing’s College London, October 11, 2022
New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London and others has found an association between fathers who experience too much stress in the months following the birth of their child, and the child’s subsequent development of emotional and behavioral problems at age two.
The research, published in the Journal of Child Psychology and Psychiatry, suggests that new fathers should be assessed for stress during the perinatal period as it presents an opportunity for early intervention to help prevent future difficulties for both father and child.
901 fathers and 939 mothers completed questionnaires on stress, anxiety and depression during pregnancy and three stages in the postpartum period, with a final survey taking place at 24 months.
Overall, around 7% of participating fathers experienced high stress at the first three stages measured in the perinatal period. This then rose to 10% at two years postpartum.
Researchers identified the strongest association between paternal stress at three months postpartum and childhood emotional and behavioral problems at age two, even when accounting for other factors like maternal stress, anxiety and depression. Paternal stress was more strongly associated with childhood outcomes than paternal depression or anxiety.
Dr. Fiona Challacombe, and lead author of the study says, “Our study found that paternal stress makes a unique contribution to child outcomes, particularly during the early postpartum months. Nonetheless, men may be reluctant to seek help or express their needs during this time and may feel excluded from the maternal focus of perinatal services. The rise in paternal stress at two years indicates that this does not dissipate over time—returning to work, chronic sleep difficulties and behavioral difficulties becoming more apparent may all contribute.”
Stevia – A Natural Alternative For Your MetabolismAutonomous University of Yucatan (Mexico), September 28, 2022
Stevia’s health benefits go beyond sugar reduction — it could also be a natural alternative for treating metabolic disorders, such as obesity and type 2 diabetes, say researchers. If you’re determined to sweeten your foods and beverages, consider using this amazing natural herb.
Publishing their findings in the peer-reviewed Journal of Medicinal Food, the Mexican researchers reviewed both in vitro and in vivo studies which looked at the beneficial effects reported for steviol compounds — aqueous and alcoholic stevia extracts — derived from the leaves, flowers and roots of the stevia plant.
These studies analysed the plant’s anti-obesity, anti-hyperglycemic, anti-hypertensive and anti-hyperlipidemic effects, all of which make it interesting to tackle the symptoms of metabolic syndrome. This is characterised by factors such as abdominal obesity, inflammation and diabetes, that are associated with an increased risk of cardiovascular diseases.
Stevia contains other compounds, such as phytochemicals, that provide beneficial properties to health.
Theses include: diterpenes, labdabos, triterpenes, stigmasterol, tannins, ascorbic acid, alkaloids, steroids, saponins, flavonoids, b-carotene, chromium, cobalt, magnesium, iron, potassium, phosphorus, riboflavin, thiamine, tin, zinc, apigenin, austroinilina, avicularin, b-sitosterol, caffeic acid, campesterol, caryophyllene, centaureidin, chlorogenic acid, chlorophyll, kaempferol, luteolin and quercetin.
The authors identify three separate rat or mice studies in which orally administered stevia for a period of between three and nine weeks led to a weight reduction.
One study looking for sucrose replacement in beverages found that that satiety levels of SR, aspartame, and saccharose were similar among each other but stevia reduced the glucose and postprandial insulin levels, write the authors.
Other human and animal studies identified stevia as beneficial in lowering blood pressure. For instance, one study, hypertensive patients were given 250 mg of steviosides for one year. “Results indicate that their systolic and diastolic APs decreased after 3 months of starting the treatment without any negative effect on the biochemical parameters.”
Did the COVID-19 pandemic lead to changes in our personality traits?University of Illinois, October 1, 2022
Previous studies have shown that levels of neuroticism declined during the early stages of the COVID-19 pandemic in 2020. A new study published in PLOS One found that these changes in neuroticism were short-lived and normalized later in the pandemic in 2021-2022.
However, other personality traits such as agreeableness, openness, extraversion, and conscientiousness declined during the later stages of the COVID-19 pandemic in 2021-2022.
The study found that younger individuals were especially susceptible to changes in personality traits during the pandemic, suggesting a disruption of the personality development and maturation process that normally occurs during young adulthood.
The five-factor model of personality is a widely used model that describes personality based on the presence of five broad traits. The model includes the following five personality traits:
Extraversion — a tendency for outgoing, energetic, and assertive behaviorsNeuroticism — a tendency for persistent and excessive pessimism and anxietyConscientiousness — a tendency to be organized, self-disciplined, responsible, and hard-workingAgreeableness — a tendency to be empathetic, friendly, compliant, and trustworthyOpenness — a tendency to be curious, imaginative, and open-mindedThese personality traits remain relatively stable over an adult’s lifetime and are generally unaffected by personal experience. Previous studies have shown that individuals show a small change in personality traits with age. Specifically, conscientiousness and agreeableness tend to increase gradually with age, whereas neuroticism, openness, and extraversion tend to decrease.

The Gary Null Show - 10.11.22

VIDEOS:
Serious Adverse Events & Side Effects: Silence is inexcusable (4:51)
Words From Aaron Siri on CDC Data On Covid Vaccines – (1:10 – 2:47)
Bill Clinton and Blackrock team up to ACCELERATE the great reset | Redacted with Clayton Morris
Neil Oliver – ‘…digital enslavement is coming…’ (4:46-19:06)
Tulsi Gabbard leaves Democratic Party, denounces it as ‘elitist cabal’ (0:20 – 2:49)
 
Resveratrol supplementation linked to better blood lipidsSoutheast University (China), October 10 2022.
A meta-analysis of randomized, controlled trials published in the journal Nutrients found an association between lower lipids and supplementing with resveratrol, a nonflavonoid polyphenol compound found in grapes, knotweed and other plants.
Researchers at Southeast University in Nanjing, China identified 17 trials that included a total of 968 men and women for their meta-analysis. Resveratrol doses ranged from 10 to 3,000 milligrams per day administered from 4 to 48 weeks.
The meta-analysis revealed a significant association between resveratrol supplementation and reductions in total cholesterol, low-density lipoprotein (LDL) cholesterol and triglyceride levels. The reduction in LDL cholesterol associated with resveratrol was significantly greater in trials of at least 12 weeks duration, trials that administered dosages of 500 milligrams resveratrol per day or more and among people with type 2 diabetes. The researchers did not find an association between supplementing with resveratrol and “good” high-density lipoprotein (HDL) cholesterol levels.
“This meta-analysis indicated that the supplementation of resveratrol could significantly affect the serum levels of total cholesterol, LDL-cholesterol and triglycerides, but not the level of HDL-cholesterol,” they concluded. “Findings from this meta-analysis could be helpful for providing suggestions for the use of resveratrol as nutraceutical.”
A Mulberry Component, Prevents SARS-CoV-2 Infection by Blocking the Interaction between SARS-CoV-2 Spike Protein S1 Receptor-Binding DomainKorea Institute of Oriental Medicine, September 28, 2022
Despite the recent development of RNA replication-targeted COVID-19 drugs by global pharmaceutical companies, their prescription in clinical practice is limited by certain factors, including drug interaction, reproductive toxicity, and drug resistance. Natural products are a potential source of molecules with therapeutic effects against COVID-19.
In this study, we investigated the inhibitory efficacy of mulberrofuran G (MG), a component of mulberry, which has been used as food and traditional medicine, on the binding of the spike S1 receptor-binding domain (RBD) protein to the angiotensin-converting enzyme 2 (ACE2) receptor, which is the initial stage of the SARS-CoV-2 infection. In competitive enzyme-linked immunosorbent assays, MG effectively blocked the spike S1 RBD: ACE2 receptor molecular binding, and investigations using the BLItz system and in silico modeling revealed that MG has high affinity for both proteins.
Finally, we confirmed that MG inhibits the entry of SARS-CoV-2 spike pseudotyped virus and a clinical isolate of SARS-CoV-2 into cells, suggesting that MG might be a promising therapeutic candidate for preventing SARS-CoV-2 binding to the cell surface during early infection.
Positive childhood experiences of blue spaces linked to better adult well-beingSapienza University (Italy) & University of Exeter (UK), October 10, 2022New research based on data from 18 countries concludes that adults with better mental health are more likely to report having spent time playing in and around coastal and inland waters, such as rivers and lakes (also known collectively as blue spaces) as children. The finding was replicated in each of the countries studied.
Mounting evidence shows that spending time in and around green spaces such as parks and woodlands in adulthood is associated with stress reduction and better mental health. However, we know far less about the benefits of blue spaces, or the role childhood contact has in these relationships in later life.
The research, published in the Journal of Environmental Psychology, found that individuals who recalled more childhood blue space experiences tended to place greater intrinsic value on natural settings in general, and to visit them more often as adults – each of which, in turn, were associated with better mental wellbeing in adulthood.
Valeria Vitale, Lead author at Sapienza University of Rome, said: “In the context of an increasingly technological and industrialized world, it’s important to understand how childhood nature experiences relate to wellbeing in later life.
“Our findings suggest that building familiarity and confidence in and around blue spaces during childhood may stimulate an inherent joy of nature and encourage people to seek out recreational nature experiences, with beneficial consequences for adult mental health.”
New survey: 91% of parents say their family is less stressed when they eat togetherAmerican Heart Association & John Hopkins University, October 10, 2022Survey Highlights:
91% of parents notice their family is less stressed when they share family meals together.65% of surveyed adults say they are at least somewhat stressed, and more than a quarter (27%) are very or extremely stressed.84% of adults wish they could share a meal together more often.Overall, respondents reported eating alone about half of the time.Stress reduction, connecting with other people and taking time to slow down are identified as top benefits of mealtime.Of the 1,000 U.S. adults nationwide surveyed in September 2022 for the American Heart Association’s Healthy for GoodTM movement by Wakefield Research, the vast majority (84%) say they wish they could share a meal more often with loved ones, and nearly all parents report lower levels of stress among their family when they regularly connect over a meal.
“Sharing meals with others is a great way to reduces stress, boost self-esteem and improve social connection, particularly for kids,” said Erin Michos, M.D, M.H.S, American Heart Association volunteer, associate director of preventive cardiology at Johns Hopkins . “Chronic, constant stress can also increase your lifetime risk of heart disease and stroke, so it is important for people to find ways to reduce and manage stress as much as possible, as soon as possible.“
Connecting with friends, family, coworkers and neighbors benefits people beyond stress relief. In fact, the survey found 67% of people say sharing a meal remind them of the importance of connecting with other people, and 54% say it reminds them to slow down and take a break.
Those surveyed say they are more likely (59%) to make healthier food choices when eating with other people but have difficulty aligning schedules with their friends or family to do so, according to the survey. Overall, respondents reported eating alone about half of the time.
Study says zinc can halt the growth of cancer cellsUniversity of Texas at Arlington, September 28, 2022
Zinc supplements can significantly inhibit the proliferation of esophageal cancer cells, according to a new study co-authored by a University of Texas at Arlington researcher.
Previous studies had shown that zinc is essential for maintaining human health and protects the esophagus from cancer. However, it has never been fully understood why zinc has the ability to prevent cancer in the esophagus. In this study, a team led by Zui Pan, discovered that zinc selectively halts the growth of cancer cells but not normal esophageal epithelial cells.
“Zinc deficiency has been found in many cancer patients,” said Pan.
“But previously we didn’t know why the same physiological concentrations of zinc inhibit cancer cell growth but not normal cells. Our study, for the first time to our knowledge, reveals that zinc impedes overactive calcium signals in cancer cells, which is absent in normal cells, and thus zinc selectively inhibits cancer cell growth.” said Pan. “It now appears that zinc and calcium can have a cross talk, meaning that they can be linked.”
Zinc enriched foods include spinach, flax seeds, beef, pumpkin seeds and seafood like shrimp and oysters.
Meditation Could Protect Older People Against Alzheimer’s, Study SaysCaen-Normandy University (France), October 9, 2022
Meditation may protect older people against Alzheimer’s, the most common form of dementia, according to new research.
The ancient relaxation technique boosts brainpower among people over 65 years-old, scientists in France say. It can boost attention, awareness, and emotional health – faculties that decline with dementia.
French participants assigned to an 18-month course did better than those given English lessons instead to keep their brains busy.
“Meditation was superior to non-native language training on changing a global composite score and two of its subscores reflecting attention regulation and socio-emotional capacities,” says corresponding author Dr. Gael Chetelat from Caen-Normandy University in a statement, according to SWNS.
“The attention regulation subscore increased after meditation only,” Dr. Chetelat tells SWNS. “In the context of meditation practices, this capacity allows a heightened awareness and monitoring of the contents of experience without becoming absorbed by them. Socio-emotional capacities decreased substantially after non-native language training, suggesting the difference observed may be due to maintenance of skills by meditation.”

The Gary Null Show - 10.10.22

VIDEOS:
Paul Marik speaks about the silencing of doctors who want to speak out about the COVID vaccines (18:00)
Jeffrey Sachs: US biotech cartel behind Covid origins and cover-up ( start at 0:36)
Neil Oliver – ‘…digital enslavement is coming…’ (19:06)
New Rule: A Unified Theory of Wokeness | Real Time with Bill Maher (HBO)
 
Quinoa-Based Diet Stabilizes Blood Sugar In Older AdultsUniversity of Barcelona (Spain), October 2, 2022
According to a recent study published in the journal Nutrients, a quinoa-based diet was able to normalize glucose metabolism, and this effect was more pronounced among elderly people with impaired glucose tolerance, suggesting that quinoa is a healthy pseudocereal that is far more beneficial and nutritious than other cereal products.
This study examined the effects of a quinoa-rich diet on mediating hyperglycemia and other metabolic risk factors. Glycemic data was collected by glucose sensors operating over extended periods of time with regular prespecified recording points that could be analyzed using the functional data analysis approach to yield glucose concentrations over time.
All of the participants in this pilot study were aged 65+, without a history of diabetes, and fasting glucose levels were between 100-125 mg/dL. The participants ate grains, legumes, and tuber daily while also consuming quinoa, quinoa flakes, and quinoa flour as well as biscuits, brioche, sponge cake, baguettes, sliced bread, and pasta which all had a quinoa content of 70% or greater.
During the initial four weeks, the participants consumed their regular diets, then they were switched to the quinoa-based diet for the following four weeks, during this time all grains, grain-based products, legumes, and tubers were substituted with quinoa-based products without changing the overall composition of nutrients with exception to the cereal. During the study, all food products were provided to the participants who commonly consumed them. Additionally, eight recipes were introduced to the participants using quinoa substitutions.
At the beginning of the study most of the participants had an overweight profile, and hypertension, 45% had high blood lipids, and 33% had one or more close family members with disease. At the end of the study glucose levels were reduced before and after the quinoa-based diet, and glycated hemoglobin levels were reduced by the end of the study, as was weight and waist circumference by slight decreases.
Additional analysis revealed that multiple nutrients were associated with enhanced or reduced glucose concentrations: Gamma-tocopherol, soluble fiber insoluble dietary fiber, and ORAC were associated with enhanced glucose concentrations, while fatty acids, fructose, citric acid, cellulose, phytic acid, omega-6 PUFA, theobromine, and the proportion of total energy from proteins had a link with reduced glucose concentrations.
The nutritional profile of quinoa accounts for the difference in nutritional intake between the two diet phases. Consuming more carbs increases insulin levels, and fat storage and reduces the metabolic rate causing a cycle of fat accumulation. A high-fat diet with the same amount of calories reduces insulin secretion by triggering fat turnover in the cells making free fatty acids available for use in energy production. Dietary proteins also enhance the building of lean muscle during weight loss which also helps to expend more energy and improve the overall body composition.
Mediterranean diet improves immunotherapy response rates and progression-free survival in advanced melanoma, new study suggestsEating a Mediterranean diet, rich in fibre, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunotherapy response rates and progression-free survival in advanced melanoma patients.
University Medical Center Groningen (Netherlands), October 9, 2022
Eating a Mediterranean diet, rich in fibre, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunotherapy response rates and progression-free survival in advanced melanoma patients, a new study has found.1
Experts anticipate that the diet will play an important role in the success of immunotherapy and trials are being expanded to investigate outcomes for different tumour types, including digestive cancers.
A Mediterranean diet, containing mono-and polyunsaturated fats from olive oil, nuts and fish, polyphenols and fibre from vegetables, fruit, and wholegrains, was significantly associated with an improved response to immunotherapy drugs called Immune Checkpoint Inhibitors (ICIs). ICIs, which have been highly successful in treating melanoma, work by blocking immune system checkpoints, which then force the body’s own T-cells to attack cancers.2
The new multi-centre study by researchers from the UK and the Netherlands, recorded the dietary intake of 91 patients with advanced melanoma, who were treated with ICI drugs and monitored their progress with regular radiographic response check-ups.
As well as having a significant association with overall response rate, a Mediterranean diet was significantly associated with progression-free survival at 12 months.
The study also found that eating whole grains and legumes reduced the likelihood of developing drug induced immune-related side effects, such as colitis. In contrast, red and processed meat was associated with a higher probability of immune-related side effects.
Music practice can sharpen the brain
University of St Andrews (Scotland) October 1, 2022
A new study by researchers at the University of St. Andrews in Scotland concludes that people who practice playing musical instruments have sharper brains because they pick up mistakes in their performance and fix them more quickly than other people.
Writing about their work in a recent issue of the journal Neuropsychologia, psychologist Doctor Ines Jentzsch and colleagues suggest playing music may help guard against mental decline, either through age or disease.
“Our study shows that even moderate levels of musical activity can benefit brain functioning.” For their study, the researchers compared the mental performance of musicians versus non-musicians as they challenged them to complete simple conflict tasks.
There were 36 young adult participants in total, divided into four groups of 8 to 10, according to the number of accumulated hours of practicing a musical instrument over their lifetime (from “high,” over 5,000 hours, through “intermediate,” 2,000 to 5,000 hours and “low,” between 200 and 2,000 hours, to “no,” under 200 hours).
The researchers tested each participant’s mental ability in a single session that lasted about 2 hours. During the session, they measured the participant’s reaction times to the simple mental tasks and also took various physiological measurements.
Their results show that the amount of musical practice was positively linked to response speed – the more-practiced musicians responded faster than those with little or no musical training, with no loss in accuracy.
“This result suggests that higher levels of musical training might result in more efficient information processing in general […] and confirms earlier reports indicating a positive link between mental speed and musical ability,” write the authors.
However, what this study particularly highlights is that more hours of musical practice were also linked with “better engagement of cognitive control processes,” which came through in more efficient error and conflict detection, and reduced levels of post-error interference and post-conflict adjustments.
In other words, the more practice hours musicians had accumulated, the faster their reaction times in completing mental challenges, the better they were able to recognize and correct mistakes, and the less likely they were to go back and adjust their responses when they made mistakes.
“The research suggests that musical activity could be used as an effective intervention to slow, stop or even reverse age- or illness-related decline in mental functioning.”
3 Weeks Of Vitamin C Supplements Reduces Inflammation In Cystic Fibrosis PatientsOregon State University, October 6, 2022
Cystic fibrosis, being the aggressive disease that it is, often presents new clinical obstacles tied to treatment. Now, a new study by Oregon State University researchers may help improve patient outcomes, revealing that CF patients who take vitamin C supplements can help increase their uptake of vitamin E, which reduces inflammation.
“Cystic fibrosis is a genetic disease that is associated with increased inflammation, and like many inflammatory diseases, it comes with a large amount of oxidative stress,” says Maret Traber of OSU’s Linus Pauling Institute in a university release.
Traber also notes that CF patients have difficulty absorbing fat, limiting their body’s ability to use fat-soluble vitamins like vitamin E. This generally means that this patient population has to take in more fat than an average person to break even. Studies have connected vitamin C to reducing inflammation and making use of oxidized vitamin E that the body wouldn’t otherwise absorb.
The team found that after 3.5 weeks of daily vitamin C supplementation at a dose of 1,000 milligrams, the patients had lower concentrations of malondialdehyde (MDA), which is a marker of oxidative stress. Additionally, they noticed that vitamin E wasn’t leaving the bloodstream as quickly.
These findings aren’t just promising for CF patients, but also for smokers and people with metabolic syndrome since they normally also struggle with oxidative stress in their bodies, which may also suggest that vitamin C and E supplements could help them find relief. Traber also explains that while this study reinforces that getting ample vitamin C and E through a varied and nutritious diet is important, the effects have more to do with adding high amounts of vitamin C to a healthy diet.
“This study used vitamin C far in excess of what someone can easily obtain from the diet,” Traber concludes. “One thousand milligrams is the equivalent of 15 oranges or four or five medium bell peppers. But the research does suggest a high dosage may be beneficial in inflammatory conditions.”
Link Found Between High-Fat, High-Calorie Diet and Pancreas Cancer
University of California Los Angeles, Oct. 1, 2022
Researchers at UCLA’s Jonsson Comprehensive Cancer Center (JCCC) have found that mice made obese by being given high-calorie, high-fat diets (HFCD) developed abnormally high numbers of lesions known as pancreatic intraepithelial neoplasias (PanINs), which are known to be precursors to pancreas cancer. This is the first study to show a direct causative link in an animal model between obesity and risk of this deadly cancer.
Cancer of the pancreas (scientifically known as pancreatic ductal adenocarcinoma or PaCa) is one of the most deadly forms of the disease in humans. Overall five-year survival rates are approximately three to five percent and the average survival period after diagnosis is just four to six months. It is a particularly aggressive disease and often beyond the point of effective treatment by the time symptoms appear.
Dr. Eibl and colleagues set out to develop diet-induced obesity and development of pancreas cancer in a set of mice and then compare them to another set of mice that are genetically identical but not given a high-fat, high-calorie diet. Obesity in these mice resembles several important clinical features of human obesity such as weight gain and disturbance of metabolism, and this mouse model was ideal for unraveling any underlying biological mechanisms of pancreas cancer that are put in motion by obesity.
Mice that ate the normal diet gained an average of approximately 7.2 grams, plus or minus approximately 2.8 grams over 14 months. Mice that ate the high-fat, high-calorie diet gained an average of 15.9 grams, plus or minus 3.2grams. Mice fed the normal diet had mostly normal pancreases with very few scattered PanIN lesions. Mice fed the high-fat, high-calorie diet had significantly more PanIN lesions and fewer overall healthy pancreases.
The study showed that the mice fed a diet high in fats and calories gained significantly more weight, had abnormalities of their metabolism and increased insulin levels, and had marked pancreatic tissue inflammation and development of PanIN lesions. These observations strongly suggest that such a diet leads to weight gain, metabolism disturbances, can cause pancreas inflammation and promotes pancreas lesions that are precursors to cancer.
“The development of these lesions in mice is very similar to what happens in humans,” Dr. Eibl said. “These lesions take a long time to develop into cancer, so there is enough time for cancer preventive strategies, such as changing to a lower fat, lower calorie diet, to have a positive effect.”
The vegetable that treated gunshot woundsNational Geographic, October 9, 2022
One of the most expensive meals ever eaten—barring Cleopatra’s show-stopping vinegar cocktail with dissolved pearl—was an onion.
At least, the eater thought it was an onion. He was a (nameless) sailor in the 1630s, on board a ship transporting a cargo of tulip bulbs at the height of the European tulip craze. Now nicknamed tulipomania, this was the dot-com bubble of the day, in which speculators drove the price of tulip bulbs, recently introduced from the seraglios of the Middle East, to unsustainably astronomical heights. (Predictably, the market crashed, leaving many tulip investors ruined.) The clueless sailor, who said only that he thought his meal remarkably blah-tasting for an onion, had chowed down on a bulb of Semper Augustus, then worth 5,500 florins—a fortune on the open market.
It’s an interesting story because, frankly, it’s hard to miss an onion. Onions—members of the odoriferous Allium genus that includes some 700 species, among them garlic, leeks, shallots, chives, rakkyo, and kurrats—are crammed with smelly, eye-stinging, volatile chemicals that are distinctly absent from tulip bulbs. Collectively, these pack such a powerful sensory punch that onions and relatives have an historical reputation for effectively fending off everything from devils, demons, and vampires to witches, serpents, tigers, the black plague, and the common cold.
Onions, traditionally, have also been known as fighting food. Onions were fed to Greek athletes in training for the brutally competitive Olympics, and gladiators were massaged with onion juice before entering the arena. The Roman legions, who had a passion for all things onion, distributed alliums across Europe. (One authority claims that it’s possible to follow the advance of the Roman Empire by plotting range maps for garlic.) For the legionnaires, alliums were not only tasty, but militarily helpful, believed to promote strength and courage in face of the enemy. In ancient times, gamecocks and warhorses were fed garlic to boost their fighting spirit; and in Aristophanes’s 5th-century BCE play The Knights, warriors stuff themselves with garlic in preparation for battle. Garlic, in Rome, was dedicated to Mars, the god of war.
Onions themselves are fine-tuned biological fighting machines. The compounds generated when an onion is bitten, nibbled, sliced, chopped, diced, or otherwise disrupted are the onion’s anti-pest defense mechanism, a phenomenal battery of repellants nasty enough to discourage most onion attackers from ever coming back again. When onion cells are damaged, the onion goes into red alert, releasing enzymes that act upon ordinarily benign sulfur-containing organic compounds to produce a barrage of malodorous, painful, and highly reactive molecules. It doesn’t pay to mess with an onion.
The Onion Equivalent of Tear GasSome allium-generated chemicals simply smell awful: onions and garlic, for example, contain some of the same sulfurous ingredients found in skunk spray. (American cowboys once called onions skunk eggs.) Others make us cry. An abused onion undergoes chemical reactions that lead to the production of syn-propanethial-S-oxide—known as a lachrymator, from the Latin lacrima meaning “tear.” Fast-acting and potent, syn-propanethial-S-oxide, is the onion equivalent of tear gas.
When syn-propanethial-S-oxide hits the cornea of the eye—which happens within seconds of chopping knife meeting onion—it activates nerve endings that, detecting an irritant, send a signal to the lachrymal glands to pump out tears to wash the invader away. And well it should; onion irritant is really irritating. Chemist and onion expert Eric Block compares its effect to a punch in the eye-socket. Combined with the water in tears, syn-propanethial-S-oxide breaks down to make sulfuric acid, which is something nobody wants in the eye. Solutions to the onion-slicing lachrymator problem—none of them totally foolproof—include goggles, fans, or dicing up your onion under cold running water.
Mean as onions are, they’ve got a lot going for them. Onion and garlic juices are both mild antibiotics. In the Civil War, onion juice was routinely used to treat gunshot wounds. General Grant, deprived of it, sent a testy memo to the War Department in Washington: “I will not move my troops without onions.” (They promptly sent him three cartloads.) Garlic was used as an antiseptic in both World Wars I and II.
Modern research shows that these weren’t bad picks in a medical pinch: garlic juice, for example, inhibits Streptococcus, Staphylococcus, and the causative agents of typhus and dysentery. Alliums, if not optimal, were certainly better than nothing.
Healing Properties of OnionsToday onions are considered more than food. They’re now touted as nutraceuticals—a portmanteau word cobbled together from “nutrient” and “pharmaceutical”—indicating that as well as adding flavor to spaghetti sauce and stew, they also have substantial medicinal and health-promoting qualities. Onions not only inhibit bacterial and fungal growth, but are laden with antioxidants, effective at protecting us from cancers and cardiovascular disease. Various chemicals in the versatile onion have been found to ameliorate everything from allergies and asthma to diabetes; and onions are lush sources of vitamins and minerals.
Foodwise, it’s hard to imagine living without onions. Onions are essential components of any number of global cuisines. Perhaps the best plug for the culinary versatility of the onion is the story of the 18th-century French caterer who-faced with hungry customers and nothing in the larder-served up a pair of leather gloves, shredded, and sautéed with onions, mustard, and vinegar. The recipients thought it delicious.
Nowadays we may soon even be able to have all the pleasures and perks of onions without the pain. Colin Leady and colleagues, of New Zealand’s Crop and Food Research, along with collaborators in Japan, have come up with a tear-free onion. It was created using a gene-silencing technology in which the gene for the enzyme that generates the onion lachrymator is shut down. The result is an onion with all the flavorful and nutritional bennies of a conventional onion, but without the tear-inducing syn-propanethial-S-oxide.

The Gary Null Show - 10.07.22

VIDEOS:
COVID-19 VACCINATED PEOPLE SUFFERING STRANGE HALLUCINATIONS BEFORE COLLAPSING – 7:15
WHISTLEBLOWER NURSE IN WASHINGTON DESCRIBES VACCINE INJURIES FROM EMPLOYMENT MANDATE – 1:45
FUNERAL EMBALMER: 85% OF DEAD BODIES NOW HAVE STRANGE BLOOD CLOTS SINCE COVID VACCINE ROLL-OUTS – 15:20
“UNEXPLAINED DEATHS” BECOMING #1 CAUSE OF DEATH IN 2022 IN CANADA, AUSTRALIA, AND EUROPE – 5:26
Jay Bhattacharya: The legal case against Anthony Fauci 
 
Rhodiola found to be an effective herbal medicine for treating fatigue and weaknessNational Academy of Medical Sciences of Ukraine, September 28, 2022
With everything that’s going on in life, it’s normal to feel tired at some point. Fatigue is a condition characterized by extreme feelings of either physical or mental tiredness. One study shows that rhodiola (Rhodiola rosea) can be used as an herbal medicine for fatigue.
People who are experiencing fatigue can have symptoms like sore muscles, lack of motivation, headaches, drowsiness, and irritability. If fatigue lasts for one to six months it can be classified as prolonged fatigue. However, if it goes beyond that it is already classified as chronic fatigue. Studies show that a third of the adult population has experienced chronic fatigue at least once in their life. With the high prevalence of chronic fatigue, it is unfortunate that there is still no standard medication available for it.
Previous studies have shown that rhodiola can reduce symptoms in people suffering from mental fatigue. In addition to this, animal studies have also revealed that rhodiola can stimulate physical work capacity.
For this study, which was published in Complementary Medicine Research, the researchers looked at rhodiola as a potential medication for prolonged and chronic fatigue. Researchers performed a clinical trial with 100 participants suffering from either prolonged or chronic fatigue. Although the trial lasted for eight weeks, significant improvements in fatigue symptoms were already observable after just one week. Further improvements could still be observed throughout the trial period. Furthermore, no adverse effects were observed with rhodiola intake.
Parenting practices in teen years set the stage for closeness, warmth later onPenn State University, October 5, 2022High-quality parenting practices in adolescence lay the foundation for close parent-child relationships when the children become young adults, according to new research from Penn State.
The study is one of the first to examine how changes in parental involvement, parental warmth, and effective discipline during adolescence predict the quality of the relationships between parents and their young adult children, said Greg Fosco, professor of human development and family studies and associate director of the Edna Bennett Pierce Prevention Research Center at Penn State, who was co-principal investigator on the study.
The study’s findings were published recently in Developmental Psychology. The research team surveyed 1,631 participants in a long-term research study of families in rural and semi-rural Pennsylvania and Iowa who completed surveys between sixth and 12th grades and again at age 22.
“Our research showed that parenting can change a lot during the teenage years: parents often express less warmth and affection, spend less time with their teens, and become more harsh in their discipline. Parents that were able to maintain positive parenting and involvement laid the foundation for a close relationship when their teens became adults,” said Fosco.
Staying involved in teens’ lives may look different than when they were younger, and it can be challenging to stay close with teens as they seek greater independence and autonomy, Fosco acknowledged. Based on the study’s findings, he suggested these activities:
Do something together, like playing sports, bike riding, exercising, going for a walk, gaming, cooking, attending events, or going out for a meal or dessert.Work on a project together around the house.Talk about what’s going on at school.Discuss what you want to do in the future.Further, adolescents who experienced higher levels of parental warmth in the early teen years reported feeling more closeness and warmth with mothers and fathers when they were in their 20s, Fosco said.
The study also found that parents who were skilled at using effective discipline with their sixth grade children — and maintained these effective practices over the course of adolescence — had less conflictual relationships when their children were in their 20s.
Lifestyle Influences Metabolism Via DNA Methylation
Helmholtz Zentrum Munchen (Germany) September 20, 2022
An unhealthy lifestyle leaves traces in the DNA. These may have specific effects on metabolism, causing organ damage or disease. Scientists of Helmholtz Zentrum München have now identified 28 DNA alterations associated with metabolic traits. This world-first epigenome-wide association study (EWAS) of modified genes and metabolites has been now published in the journal Human Molecular Genetics.
In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence. Such processes can influence gene function and are known as epigenetics.
To this end, the team analyzed blood samples from more than 1800 participants of the KORA study *. In doing so, they analyzed more than 457,000 loci in the DNA as to biochemical alterations and compared them with the concentrations of 649 different metabolites. The analysis showed that the methylation of 28 DNA segments changed a number of important metabolic processes.
In the relevant DNA regions there were also already known disease-related genes: for example, the TXNIP gene that regulates glucose metabolism and is associated with the development of diabetes mellitus. Appropriately, with the methylated TXNIP there were altered concentrations of metabolites from the lipid and glucose metabolism. Also genes that are known to be biochemically altered due to smoking affect different metabolic activities, and specifically those with corresponding biological functions.
“This study gives us new insights into how lifestyle factors can influence metabolism via the resulting alterations in the DNA,” said Gieger, research group leader at the IGE. “We can now use these results to develop new diagnostic and therapeutic approaches for lifestyle-related diseases such as diabetes.”
Exposure to fluoridated water and attention deficit hyperactivity disorder prevalence among children and adolescents in the United States: an ecological associationYork University (Ontario), September 30, 2022Epidemiological and animal-based studies have suggested that prenatal and postnatal fluoride exposure has adverse effects on neurodevelopment. The aim of this study was to examine the relationship between exposure to fluoridated water and Attention-Deficit Hyperactivity Disorder (ADHD) prevalence among children and adolescents in the United States.Methods: Data on ADHD prevalence among 4-17 year olds collected in 2003, 2007 and 2011 as part of the National Survey of Children’s Health, and state water fluoridation prevalence from the Centers for Disease Control and Prevention (CDC) collected between 1992 and 2008 were utilized.Results: State prevalence of artificial water fluoridation in 1992 significantly positively predicted state prevalence of ADHD in 2003, 2007 and 2011, even after controlling for socioeconomic status. A multivariate regression analysis showed that after socioeconomic status was controlled each 1% increase in artificial fluoridation prevalence in 1992 was associated with approximately 67,000 to 131,000 additional ADHD diagnoses from 2003 to 2011. Overall state water fluoridation prevalence (not distinguishing between fluoridation types) was also significantly positively correlated with state prevalence of ADHD for all but one year examined.Conclusions: Parents reported higher rates of medically-diagnosed ADHD in their children in states in which a greater proportion of people receive fluoridated water from public water supplies. The relationship between fluoride exposure and ADHD warrants future study.

The Gary Null Show - 10.06.22

VIDEOS:
Hang on, the WEF is now doing THIS to our internet? | Redacted with Clayton Morris – 7:00
This intense AI anger is exactly what experts warned of, w Elon Musk. – 15:01
New Brain Implant Begins Human Trials – Neuralink Update! – 14:00 
Get the latest information from the CDC about COVID-19. Professor Sucharit Bhakdi, M.D – 10:00 
Study links omega-3s to improved brain structure, cognition at midlifeUniversity of Texas Health Science Center, October 5, 2022
Eating cold-water fish and other sources of omega-3 fatty acids may preserve brain health and enhance cognition in middle age, new evidence indicates.
Having at least some omega-3s in red blood cells was associated with better brain structure and cognitive function among healthy study volunteers in their 40s and 50s, according to research published in Neurology®, the medical journal of the American Academy of Neurology.
“Studies have looked at this association in older populations. The new contribution here is that, even at younger ages, if you have a diet that includes some omega-3 fatty acids, you are already protecting your brain for most of the indicators of brain aging that we see at middle age,” said Claudia Satizabal, PhD the lead author of the study.
Volunteers’ average age was 46. The team looked at the relation of red blood cell omega-3 fatty acid concentrations with MRI and cognitive markers of brain aging. Researchers also studied the effect of omega-3 red blood cell concentrations in volunteers who carried APOE4, a genetic variation linked to higher risk of Alzheimer’s disease.
The study of 2,183 dementia- and stroke-free participants found that:
Higher omega-3 index was associated with larger hippocampal volumes. The hippocampus, a structure in the brain, plays a major role in learning and memory.Consuming more omega-3s was associated with better abstract reasoning, or the ability to understand complex concepts using logical thinking.APOE4 carriers with a higher omega-3 index had less small-vessel disease. The APOE4 gene is associated with cardiovascular disease and vascular dementia.“Omega-3 fatty acids such as EPA and DHA are key micronutrients that enhance and protect the brain,” said study coauthor Debora Melo van Lent, PhD, postdoctoral research fellow at the Biggs Institute. “Our study is one of the first to observe this effect in a younger population. More studies in this age group are needed.”
Multiple health benefits of b-type procyanidin-rich foods like chocolate and apples consumed in right amountsShibaura Institute of Technology (Japan), October 5, 2022B-type procyanidins, made of catechin oligomers, are a class of polyphenols found abundantly in foods like cocoa, apples, grape seeds, and red wine. Several studies have established the benefits of these micronutrients in reducing the risk of cardiovascular diseases and strokes. B-type procyanidins are also successful in controlling hypertension, dyslipidemia, and glucose intolerance. Studies attest to the physiological benefits of their intake on the central nervous system (CNS), namely an improvement in cognitive functions. These physiological changes follow a pattern of hormesis—a phenomenon in which peak benefits of a substance are achieved at mid-range doses, becoming progressively lesser at lower and higher doses.
Researchers from Shibaura Institute of Technology (SIT), Japan, led by Professor Naomi Osakabe, reviewed the data from intervention trials supporting hormetic responses of B-type procyanidin ingestion. The team conducted in vivo experiments to understand possible connections between B-type procyanidin hormetic responses and CNS neurotransmitter receptor activation. Their article has been published in Frontiers of Nutrition .
The researchers noted that a single oral administration of an optimal dose of cocoa flavanol temporarily increased the blood pressure and heart rate in rats. But the hemodynamics did not change when the dose was increased or decreased. Administration of B-type procyanidin monomer and various oligomers produced similar results. According to Professor Osakabe, “These results are consistent with those of intervention studies following a single intake of food rich in B-type procyanidin, and support the U-shaped dose-response theory, or hormesis, of polyphenols.”
To observe whether the sympathetic nervous system (SNS) is involved in the hemodynamic changes induced by B-type procyanidins, the team administered adrenaline blockers in test rats. This successfully decreased the temporary increase in heart rate induced by the optimal dose of cocoa flavanol. A different kind of blocker—a1 blocker—inhibited the transient rise in blood pressure. This suggested that the SNS, which controls the action of adrenaline blockers, is responsible for the hemodynamic and metabolic changes induced by a single oral dose of B-type procyanidin.
The researchers next ascertained why optimal doses, and not high doses, are responsible for the thermogenic and metabolic responses. They co-administered a high dose of cocoa flavanol and yohimbine (an α2 blocker) and noted a temporary but distinct increase in blood pressure in test animals. Similar observations were made with the use of B-type procyanidin oligomer and yohimbine. Professor Osakabe surmises, “Since α2 blockers are associated with the down-regulation of the SNS, the reduced metabolic and thermogenic outputs at a high dose of B-type procyanidins seen in our study may have induced α2 auto-receptor activation. Thus, SNS deactivation may be induced by a high dose of B-type procyanidins.”
Meditation keeps emotional brain in check
Michigan State University, September 29, 2022
Meditation can help tame your emotions even if you’re not a mindful person, suggests a new study from Michigan State University.
Reporting in the journal Frontiers in Human Neuroscience, psychology researchers recorded the brain activity of people looking at disturbing pictures immediately after meditating for the first time. These participants were able to tame their negative emotions just as well as participants who were naturally mindful.
“Our findings not only demonstrate that meditation improves emotional health, but that people can acquire these benefits regardless of their ‘natural’ ability to be mindful,” said Yanli Lin, an MSU graduate student and lead investigator of the study. “It just takes some practice.”
Researchers assessed 68 participants for mindfulness using a scientifically validated survey. The participants were then randomly assigned to engage in an 18-minute audio guided meditation or listen to a control presentation of how to learn a new language, before viewing negative pictures (such as a bloody corpse) while their brain activity was recorded.
The participants who meditated – they had varying levels of natural mindfulness – showed similar levels of “emotion regulatory” brain activity as people with high levels of natural mindfulness. In other words their emotional brains recovered quickly after viewing the troubling photos, essentially keeping their negative emotions in check.
In addition, some of the participants were instructed to look at the gruesome photos “mindfully” (be in a mindful state of mind) while others received no such instruction. Interestingly, the people who viewed the photos “mindfully” showed no better ability to keep their negative emotions in check.
This suggests that for non-meditators, the emotional benefits of mindfulness might be better achieved through meditation, rather than “forcing it” as a state of mind, said Moser, MSU associate professor of clinical psychology and co-author of the study.
A mother’s ultra-processed food intake may be linked to obesity risk in her childrenMassachusetts General Hospital and Harvard Medical School, October 5, 2022
A mother’s consumption of ultra-processed foods appears to be linked to an increased risk of overweight or obesity in her offspring, irrespective of other lifestyle risk factors, suggests a U.S. study published by The BMJ today.
The researchers that mothers might benefit from limiting their intake of ultra-processed foods, that dietary guidelines should be refined, and financial and social barriers removed to improve nutrition for women of childbearing age and reduce childhood obesity.
Researchers drew on data for 19,958 children born to 14,553 mothers (45% boys, aged 7-17 years at study enrollment) from the Nurses’ Health Study II (NHS II) and the Growing Up Today Study (GUTS I and II) in the United States.
The results show that a mother’s ultra-processed food consumption was associated with an increased risk of overweight or obesity in her offspring. For example, a 26% higher risk was seen in the group with the highest maternal ultra-processed food consumption (12.1 servings/day) versus the lowest consumption group (3.4 servings/day).
Reishi Mushrooms Proven For Fibromyalgia Pain Relief In Human StudyUniversity of Extremadura (Spain), September 29, 2022
A promising double-blind, randomized human clinical study of ganoderma lucidum, also known as reishi mushroom, has been shown to be effective in treating fibromyalgia chronic pain.
To begin, science knows that the reishi mushroom is the most studied nutraceutical and that it has been used safely and effectively for thousands of years. It is often called the mushroom of longevity and immortality.
Reishi has several biologically-active compounds in it, including triterpenes, which have been shown to increase the production of Nerve Growth Factor. NGF is a protein that helps to create new neurons and repair damaged neurons. This also enhances the communication between cells and reduces inflammation.
In the fibromyalgia chronic pain study, one group consumed 6 grams of reishi mushroom powder per day and another group consumed 6 grams of carob powder per day. Each group participated for 6 weeks and continued to self-report their experiences for 72 days after the treatment. The reishi mushroom group experienced pain reduction by up to 30%, which is significant.
They also reported getting better sleep, were happier and gained aerobic endurance and body flexibility.
Time-restricted eating improves health of firefightersSalk Institute, October 3, 2022In collaboration with the San Diego Fire-Rescue Department, scientists from the Salk Institute and UC San Diego Health conducted a clinical trial and found that time-restricted eating improved measures of health and well-being in firefighters. The lifestyle intervention only required the firefighters to eat during a 10-hour window and did not involve skipping meals.
The new findings, published in Cell Metabolism may also have implications for shift workers, such as military personnel; health care, food service, and transportation professionals; telecommunications staff; and new parents, whose schedules often mimic shift work when caring for a new baby.
“Doctors and researchers are always thinking about the magic pill that can cure or reduce disease. Our study showed that shift workers with high blood pressure, blood sugar, or cholesterol can benefit from a simple lifestyle intervention called time-restricted eating,” says Salk Professor Satchidananda Panda, co-corresponding author of the study and holder of the Rita and Richard Atkinson Chair.
Almost every cell in the body has a 24-hour biological clock that produces circadian (daily) rhythms. These rhythms regulate behavior (e.g., when to be active and when to rest) and physiology (e.g., blood pressure, blood sugar, muscle function). Circadian rhythms coordinate with the environment in part by regular, timed cycles of light and dark and eating and fasting. Disruptions to these cycles, which can occur with shift work, can impact health, leading to obesity, heart disease, diabetes, and cancer.
In this clinical trial, 150 firefighters from the San Diego Fire-Rescue Department used the myCircadianClock app on their phones to track their eating for three months. Half the group ate within a 10-hour window, while the other half (the control group) changed nothing and ate within a 14-hour window. Both groups were encouraged to follow a Mediterranean diet, which is known to have health benefits. The study included both individuals who were healthy and those who were overweight or who had health conditions such as high blood pressure, cholesterol, and/or blood glucose.
The researchers found that time-restricted eating within a 10-hour eating window was feasible without adverse effects and helped the firefighters significantly decrease their VLDL (“bad”) cholesterol size by 1.34 nanometers (small VLDL is less likely to block arteries), improve their mental health, and reduce their alcohol intake by roughly three drinks per week. Time-restricted eating also significantly improved blood sugar and blood pressure in firefighters who had elevated levels at the start of the study. The researchers concluded that time-restricted eating may provide even greater benefit for those at risk for cardiometabolic disease and other chronic diseases.