The Gary Null Show

The Gary Null Show - 10.05.22

VIDEOS:
Unpayable Debt & Deadly Vax Causing Hell on Earth – Ed Dowd – start 6:30 -20:00
What Greta Thunberg does not understand about climate change | Jordan Peterson – 7:09
Gary Null – Speaks to U.N. on Earth Day (Part 2 of 2) – 9:30
Neil Oliver: ‘By taking back control of the money we can begin regaining control of our world’ 
Breast health linked to eating peanut butter and nuts
Washington University School of Medicine, September 27, 2022
By eating more peanut butter during their high school years, girls could be improving their breast health in adulthood, according to a US study published recently in the journal Breast Cancer Research and Treatment.
Dr. Graham Colditz, of Washington University School of Medicine in St. Louis, and colleagues found that girls aged 9 to 15 who ate peanut butter and nuts twice a week were 39% less likely to develop benign breast disease by the age of 30 than girls who did not.
Benign breast disease includes lumps or tender spots that turn out to be fibrous tissue and/or cysts, as well as other conditions like hyperplasia, an overgrowth of the cells that line the ducts in the glandular breast tissue. Although benign breast disease is not cancerous, it can raise the risk of developing breast cancer later in life.
For their study, he and his colleagues looked at health data on over 9,000 American schoolgirls recruited to The Growing Up Today Study.  The data also included reports from the girls between when they were 18 to 30 years old, that indicated whether they had ever been diagnosed with biopsy-confirmed benign breast disease.
When they compared the two sets of data, the researchers found that participants who had eaten peanut butter or nuts twice a week were 39% less likely than peers who never ate those foods to receive a diagnosis for benign breast disease.
The data suggest pulse foods – soy and other beans and lentils – and corn may also be linked to reduced risk of benign breast disease, but because they did not feature as much in the diets of these girls, the evidence was not so strong.And they concluded that “consumption of vegetable protein, fat, peanut butter, or nuts by older girls may help reduce their risk of BBD [benign breast disease] as young women.”
Pine bark extracts may help curb age-related muscle loss; Study
D’Annunzio University (Italy), September 28, 2022
Supplements containing the French maritime pine bark extract Pycnogenol may help stabilize muscle loss, support muscular function, and boosts daily muscle endurance, says a new study.
Data from a study with 64 healthy seniors aged 70-78 indicated that 150 mg per day of Pycnogenol may improve muscle function and endurance in a range of everyday activities, from carrying items to climbing stairs and walking.
Results published in Minerva Ortopedica e Traumatologica also indicated that supplementation with the pine bark was associated with a reduction in oxidative stress of 14%. Oxidative stress is reportedly a common measurement of sarcopenia which prevents the body from normal detoxifying and repair.
“Supplementation with Pycnogenol – suppressing the excess in oxidative stress and controlling muscular pain and fatigue – possibly in association with some specific protein and vitamins supplementation, may produce faster muscular replacement and muscular remodeling improving physical functions and fitness. In this study, muscle loss appeared to be controlled and reduced,” wrote the authors from Irvine3 Labs and D’Annunzio University in Italy.
Sarcopenia
Muscle loss is a natural part of aging, and researchers have estimated that, after the age of 50, we lose 1-2% of our muscles each year. Strength declines as well, at a rate of 1.5% per year beginning at 50 years and accelerating to 3% after the age of 60.
Results showed that the pine bark group experienced greater muscular function and endurance in daily tasks such as carrying items (4-5 lbs) (71% improvement versus 23% in the control group), climbing stairs (52 % improvement versus 20% in the control ground) and distance walked (38% improvement versus 17% in the control group).
Supplementation with Pycnogenol was also associated with reduced proteinuria – the presence of protein in urine which, with normal kidney function, can indicate waste from muscle erosion – by 40%.
In addition, individuals who took the pine bark extract supplements demonstrated improved general fitness scores by more than 46% in comparison with the control group.
Study links prenatal phthalate exposure to reduced childhood lung function
Barcelona Institute for Global Health, October 3, 2022
A study led by the Barcelona Institute for Global Health (ISGlobal) has found that exposure to phthalates in the womb is associated with reduced lung function during childhood. The findings of the study, published in Environmental Pollution, support the European Union’s current restrictions on the use of these substances
Phthalates are chemical compounds that are widely used as plasticizers, as well as in lacquers and varnishes. They are found in a wide variety of consumer products, ranging from toys to food packaging, clothing, detergents, cosmetics, solvents, etc. Over time, phthalates in these products leach into the surrounding environment—for example, into the air, dust and food—making them virtually ubiquitous. Moreover, human exposure to phthalates starts as early as in utero, given that these compounds are able to cross the placental barrier. Phthalates act as endocrine disruptors and have been associated with numerous developmental and reproductive health problems.
“Research has consistently found that gestational phthalate exposure is associated with increased risk of childhood asthma, but the evidence on its possible association with lung function is scarce and unclear,” explained ISGlobal researcher Magda Bosch de Basea, lead author of the study.
The study included 641 mother-child pairs from the INMA Project birth cohorts in Sabadell and Gipuzkoa. Gestational phthalate exposure was analyzed using urine samples collected from the mothers during pregnancy. The children’s lung function was assessed by spirometry at various stages of development between the ages of four and eleven years.
As an indication of the ubiquity of these compounds, laboratory analyses detected all nine of the studied phthalate metabolites—i.e., substances into which phthalates are transformed once metabolized by the human body—in nearly 100% of the urine samples examined. At all stages of development, the studied metabolites were associated with decreases in two lung function parameters: forced vital capacity (FVC), which measures the maximum volume of air a person is able to exhale, and forced expiratory volume in 1 second (FEV1), which measures the maximum exhaled volume in the first second of exhalation. T
The researchers found that the associations between certain metabolites (e.g. MiBP and MBzP) and decreased lung function were generally statistically significant at younger ages, but not in spirometries performed in later years. This pattern is consistent with the findings of studies in animal models suggesting that the possible effects of these compounds on lung function revert over time.
Eating late increases hunger, decreases calories burned, and changes fat tissue
Brigham and Women’s Hospital, October 4, 2022
A new study by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, found that when we eat significantly impacts our energy expenditure, appetite, and molecular pathways in adipose tissue. Their results are published in Cell Metabolism.
“In this study, we asked, ‘Does the time that we eat matter when everything else is kept consistent?'” said first author Nina Vujović, Ph.D. “And we found that eating four hours later makes a significant difference for our hunger levels, the way we burn calories after we eat, and the way we store fat.”
Vujović, Scheer and their team studied 16 patients with a body mass index (BMI) in the overweight or obese range. Each participant completed two laboratory protocols: one with a strictly scheduled early meal schedule, and the other with the exact same meals, each scheduled about four hours later in the day. In the last two to three weeks before starting each of the in-laboratory protocols, participants maintained fixed sleep and wake schedules, and in the final three days before entering the laboratory, they strictly followed identical diets and meal schedules at home. In the lab, participants regularly documented their hunger and appetite, provided frequent small blood samples throughout the day, and had their body temperature and energy expenditure measured. To measure how eating time affected molecular pathways involved in adipogenesis, or how the body stores fat, investigators collected biopsies of adipose tissue from a subset of participants during laboratory testing in both the early and late eating protocols, to enable comparison of gene expression patterns/levels between these two eating conditions.
Results revealed that eating later had profound effects on hunger and appetite-regulating hormones leptin and ghrelin, which influence our drive to eat. Specifically, levels of the hormone leptin, which signals satiety, were decreased across the 24 hours in the late eating condition compared to the early eating conditions. When participants ate later, they also burned calories at a slower rate and exhibited adipose tissue gene expression towards increased adipogenesis and decreased lipolysis, which promote fat growth. Notably, these findings convey converging physiological and molecular mechanisms underlying the correlation between late eating and increased obesity risk.
“This study shows the impact of late versus early eating. Here, we isolated these effects by controlling for confounding variables like caloric intake, physical activity, sleep, and light exposure, but in real life, many of these factors may themselves be influenced by meal timing,” said Scheer. 
The immune system benefits from life in the countrysideAarhus University (Denmark), September 30, 2022Research from Aarhus University has demonstrated that exposure to a farming environment may prevent or dampen hypersensitivities and allergies — even in adultsAdults who move to farming areas where they experience a wider range of environmental exposures than in cities may reduce the symptoms of their hypersensitivities and allergies considerably. This is the result of new research from Aarhus University.This pioneering result was published online in the esteemed periodical, The Journal of Allergy and Clinical ImmunologyThe immune systems of people who work in farming are frequently exposed to a wide range of bacteria, fungi, pollen and other irritants which may trigger a response that protects them against hypersensitivity. Working in a farming environment may therefore serve to prevent or dampen hypersensitivity to the most widespread plant allergens: grass and birch pollen.Surprisingly, the positive effect on the immune system is seen both in people who have lived in urban environments and in adults who were born and raised in farming areas. But the real surprise is that the effect is not only seen in children:”Previously, the assumption was that only persons who had lived in farming areas while growing up would benefit from the environment’s protective effect on the immune system. But now we can demonstrate that it’s not too late simply because you are an adult,” says postdoc Grethe Elholm.It is, in other words, possible to affect the immune system and thereby the hypersensitivity which may cause allergy and allergic asthma − and what is more, this can be done at a much later point in life than previously assumed.
High Blood Pressure Linked To Faster Cognitive Decline, Dementia Risk
 
University of Michigan, October 1, 2022
High blood pressure, or hypertension, often causes people to feel perpetually stressed out or angry. Now, researchers from the University of Michigan say people with hypertension may also experience a faster deterioration in their cognitive abilities (thinking skills, decision making, memory) in comparison to those with normal blood pressure.
The team performed a “study of studies” focusing on high blood pressure’s association with declining brain function over a period of several years. They gathered and analyzed datasets collected for six large prior studies.
Originally, researchers set out to determine if fluctuations in long-term blood pressure control may somewhat explain why Hispanic Americans experience a 50-percent higher risk of developing dementia by the end of their lives in comparison to non-Hispanic white people living in the United States. Somewhat surprisingly, that study failed to produce a clear answer, as blood pressure-related cognitive decline appears to occur at about the same pace among Hispanics and Caucasians. Study authors conclude their work suggests other factors are at play regarding why Hispanics are generally more at risk of dementia.
Still, these findings make a strong case that blood pressure has a connection to cognitive outcomes later in life. Maintaining a healthy blood pressure level looks to protect thinking skills, study authors say.
“Our findings suggest that high blood pressure causes faster cognitive decline, and that taking hypertension medication slows the pace of that decline,” says lead study author Deborah Levine, M.D., M.P.H., director of the University of Michigan’s Cognitive Health Services Research Program and a professor of internal medicine at the U-M’s academic medical center, in a media release.
Researchers examined changes in the thinking and memory abilities among a group of adults (18+) who took part in six long-term studies conducted over the past five decades. Study authors enjoyed access to an average of eight years’ worth of data for each participant, including systolic blood pressure (the top number in any blood pressure reading).
The  data encompassed 22,095 non-Hispanic white adults and 2,475 Hispanic adults. None of the participants had any documented history of stroke or dementia at the time of enrollment. To start, average systolic blood pressure was lower among Hispanic adults in comparison to non-Hispanic white adults (132.5 mmHg compared with 134 mmHg). This is especially notable considering Hispanic adults in the study displayed an older average age than non-Hispanic adults (62 versus 54 years-old). Blood pressure readings tend to increase with age.
Among both Hispanics and non-Hispanics, the team observed the same pace of deteriorating thinking skills and memory linked to high blood pressure. However, when researchers focused solely on the two studies that had deliberately recruited Hispanics, they noted an undeniably faster decline in overall cognitive performance among Hispanics in comparison to the non-Hispanic white group. Importantly, though, blood pressure differences between those two groups didn’t appear to explain this cognitive decline difference. This may be due to Hispanic participants having lower blood pressure than non-Hispanic whites in these studies, researchers speculate.The study is published in the Journal of Alzheimer s Disease.

The Gary Null Show - 10.04.22

VIDEOS:
“We are on a path of escalation to nuclear war, nothing less” – Jeffrey D. Sachs – 8:46
The WEF plan to REMAKE America just got a HUGE boost from Putin | Redacted with Clayton Morris – 7:15
She admitted it. – 0:58
Google Is A Drug Company and Censors Health News 
Neil Oliver – ‘…they’re herding us towards mass conformity….’
 
Can Eating Peppers Help You Live Longer
Tulane University September 28, 2022
People who have a taste for chili peppers and other hot spicy foods may live longer, research suggests.
A new study of more than 500,000 Chinese adults over seven years finds that participants who ate foods flavored with chili peppers every day reduced their risk of premature dying by 14 percent, as compared to people who ate chili peppers less than once a week.
“Even among those who consumed spicy foods less frequently [one to two days a week], the beneficial effects could be observed,” says Lu Qi, professor of epidemiology at Tulane University. “Indeed, moderate increase of spicy foods would benefit.”
While his study, published in the BMJ, doesn’t address other foods, earlier research has indicated that horseradish, black pepper, garlic, and ginger may offer similar benefits.”There also is preliminary data from other studies showing such potential,” Qi says. Capsaicin in chili peppers may be what protects health, Qi says. It reduces risk of obesity, offers antibacterial properties, and helps protect against diabetes, cardiovascular disease, cancer, and other conditions. Chili peppers also improve inflammation and reduce blood pressure and oxidative stress.
Omega-3 may be helpful for attention, impulse control in adolescentsUniversity Pompeu Fabra (Spain), October 3 2022.
Research findings reported in European Child & Adolescent Psychiatry revealed that higher blood levels of the omega-3 fatty acids docosahexaenoic acid (DHA) and alpha-linolenic acid (ALA) were respectively associated with better test scores for attention and impulsiveness among adolescent boys and girls compared with adolescents who had lower levels.
“Polyunsaturated fatty acids are critical for brain development and function, and their deficiency may have long-term functional consequences” authors Ariadna Pinar-Marti and colleagues explained.
“Despite the established importance of DHA in brain development, few studies have evaluated whether it plays a role in the attention performance of healthy adolescents,” commented study coordinator Jordi Júlvez, PhD. “In addition, the possible role of alpha-linolenic acid (ALA), another omega-3 but of plant origin, has not been as extensively studied.”
In comparison with adolescents whose DHA levels were among the lowest one-third of participants, those whose levels were among the top third showed better attention performance as indicated by scores for reaction time and conflict response. Higher ALA levels were associated with less impulsivity. “The role of ALA in attention control is still unclear, but this finding may be clinically relevant, as impulsivity is a feature of several psychiatric conditions, such as ADHD,” Dr Pinar-Martí noted.
Weighted blankets found to increase melatoninUppsala University (Sweden), October 3, 2022
A new study from Uppsala University shows that using a weighted blanket at bedtime increases melatonin in young adults. This hormone increases in response to darkness, and some evidence suggests that it promotes sleep. The findings are published in the Journal of Sleep Research.
Previous research has shown that weighted blankets may ease insomnia in humans. Researchers from Uppsala University in Sweden experimented with 26 young men and women to examine if the bedtime use of a weighted blanket increases the production of sleep-promoting and anti-stress hormones like melatonin and oxytocin. In addition, they investigated whether the bedtime use of a weighted blanket (12% of participants’ body weight) reduced the activity of stress systems in the body. To this end, saliva was collected repeatedly from participants while they were covered with either a weighted or a light blanket to measure melatonin, oxytocin, cortisol, and the activity of the fight and flight sympathetic nervous system.
“Using a weighted blanket increased melatonin concentrations in saliva by about 30%. However, no differences in oxytocin, cortisol, and the activity of the sympathetic nervous system were observed between the weighted and light blanket conditions,” says Elisa Meth, first author and Ph.D. student at the Department of Pharmaceutical Biosciences at Uppsala University.
“Our study may offer a mechanism explaining why weighted blankets may exert some therapeutic benefits, such as improved sleep. However, our findings rely on a small sample and investigated only the acute effects of a weighted blanket. Thus, larger trials are needed, including an investigation of whether the observed effects of a weighted blanket on melatonin are sustained over longer periods,” says senior author Christian Benedict, Associate Professor of Pharmacology at the Department of Pharmaceutical Biosciences at Uppsala University.
Clinical Trial: Vegetable Extract may Treat Autism Better than Drugs
Harvard Medical School, September 30, 2022
A recent clinical trial has shown that one vegetable extract may have astounding positive effects on those with autism – broccoli extract.
Along with an extensive Autism Spectrum Disease research database at GMI, there is evidence suggesting that broccoli extract (along with avoiding heavy metals, minimizing glyphosate exposure, and eradicating the diet of gluten) shows promise in improving ASD.
The active ingredient in broccoli that seems to help is called sulforaphane, a molecule found in cruciferous vegetables such as broccoli, cabbage, and Brussels sprouts.
A groundbreaking study published in The Proceedings of the National Academy of Sciences USA titled, “Sulforaphane treatment of autism spectrum disorder (ASD),” found that a broccoli sprout extract significantly improved the behavior of boys and men (those who most often suffer from autism). Sulforaphane was selected, in part, because its physiological effects are well characterized and ideal for those with ASD:
“Dietary sulforaphane, of recognized low toxicity, was selected for its capacity to reverse abnormalities that have been associated with ASD, including oxidative stress and lower antioxidant capacity, depressed glutathione synthesis, reduced mitochondrial function and oxidative phosphorylation, increased lipid peroxidation, and neuroinflammmation.”
The placebo-controlled, randomized pilot study of 44 males, ages 13-27, showed that after 18 weeks of treatment with a sulforaphane-rich broccoli sprout extract, 46% had noticeable improvements in social interactions and 42% has improvements in verbal communication. More than half of all participants also showed a decrease in irritability, hyperactivity, and repetitive movements.
Of note, once treatment with broccoli extract stopped, most of the behaviors associated with autism returned.
The dosing schedule was determined by body weight:
· 100 lbs or less: one capsule containing 50 µmol (232 mg) of sulforaphane-rich broccoli extract was given daily
· 101–199 lbs, 100 µmol (two capsules of 232 mg each) of sulforaphane-rich broccoli extract was given daily
· More than 200 lbs: 150 µmol (three capsules of 232 mg each) of sulforaphane-rich broccoli extract was given daily
Social media use linked to developing depression regardless of personalityUniversity of Arkansas, October 3, 2022
Researchers in public policy and education recently found that young adults who use more social media are significantly more likely to develop depression within six months, regardless of personality type.
Published in the Journal of Affective Disorders Reports, the study, “Associations between social media use, personality structure, and development of depression,” was co-authored by Renae Merrill, a doctoral student in the Public Policy Program at the University of Arkansas.
This new study found strong and linear associations of depression across all personality traits.”
Among the study’s findings was that people with high agreeableness were 49% less likely to become depressed than people with low agreeableness. Additionally, those with high neuroticism were twice as likely to develop depression than those with low neuroticism when using more than 300 minutes of social media per day. More importantly, for each personality trait, social media use was strongly associated with the development of depression.
The sample of more than 1,000 U.S. adults between the ages of 18 to 30 was from data collected by Primack and his colleagues at the University of Pittsburgh.
The authors suggest that problematic social comparison can enhance negative feelings of oneself and others, which could explain how risk of depression increases with increased social media use. Engaging primarily in negative content can also enhance these feelings. And lastly, engaging in more social media reduces opportunities for in-person interactions and activities outside of the home.
“Findings from this study are important during a time of technology expansion and integration,” Merrill said. “Connecting to people virtually may increase the risk of miscommunication or misperception that leads to relationship difficulties and potential risk for developing mental health problems.”
“People have innate emotional needs for social connection and understanding,” Merrill added. “For example, social media experiences can be improved by becoming more aware of our emotions and our connection with others in various life circumstances. This awareness helps improve relationship quality by simply reaching shared meaning and understanding through more effective communication and concern for others and ourselves. Despite our differences, we have the ability to create a culture of empathy and kindness.”
Which grains you eat can impact your risk of getting heart disease earlierIsfahan University of Medical Sciences (Iran), October 3, 2022
In one of the first studies to examine the relationship between different types of grain intake and premature coronary artery disease in the Middle East, researchers found a higher intake of refined grain was associated with an increased risk of premature coronary artery disease in an Iranian population, while eating whole grains was associated with reduced risk.
According to the researchers, previous epidemiological studies have reported an association between different types of grain intake with the risk of coronary artery disease. The current study evaluated the association between refined and whole grains consumption and risk of PCAD in an Iranian population.
Premature coronary artery disease (PCAD) refers to atherosclerotic narrowing of coronary arteries in males under 55 years old or in females under 65 years old. It is often asymptomatic early in the course of the disease but may lead to chest pain (angina) and/or heart attack with progressive development of narrowing (stenosis) or plaque rupture of the arterial wall. Risk factors for PCAD include smoking, high cholesterol, high blood pressure and diabetes.
Whole grains are defined as containing the entire grain, while refined grains have been milled—ground into flour or meal—to improve shelf life but they lose important nutrients in the process. The ACC/American Heart Association Guideline on the Primary Prevention of Cardiovascular Disease recommends a diet that emphasizes the intake of vegetables, fruits, legumes, whole grains and fish to decrease heart disease risk factors.
The study recruited 2099 individuals with PCAD from hospitals with catheterization labs in different cities and ethnicities throughout Iran who underwent coronary angiography (women aged ≤ 70 and men ≤ 60). In total, 1,168 patients with normal coronary arteries were included in the control group, while 1,369 patients with CAD with obstruction equal or above 75% in at least a single coronary artery or ≥ 50% in the left main coronary artery made up the case group.
After adjusting for confounders, a higher intake of refined grains was associated with an increased risk of PCAD, while whole grain intake was inversely related to reduced risk of PCAD.

The Gary Null Show - 10.03.22

video:
Dr. Guy Mcpherson Predicts Human Extinction by 2030 
Neil Oliver: ‘By taking back control of the money we can begin regaining control of our world’
Unpayable Debt & Deadly Vax Causing Hell on Earth – Ed Dowd
2 Testimonials 
Trailer For : Science For Hire
 
Regeneration of brain stem cells boosted by turmeric compound
Institute of Neuroscience and Medicine (Germany)  September 28, 2022 
A bioactive compound found in turmeric promotes stem cell proliferation and differentiation in the brain, reveals new research published in the open access journal Stem Cell Research & Therapy. The findings suggest aromatic turmerone could be a future drug candidate for treating neurological disorders, such as stroke and Alzheimer’s disease.
The study looked at the effects of aromatic (ar-) turmerone on endogenous neutral stem cells (NSC), which are stem cells found within adult brains. NSC differentiate into neurons, and play an important role in self-repair and recovery of brain function in neurodegenerative diseases. Previous studies of ar-turmerone have shown that the compound can block activation of microglia cells. When activated, these cells cause neuroinflammation, which is associated with different neurological disorders. However, ar-turmerone’s impact on the brain’s capacity to self-repair was unknown. 
Researchers from the Institute of Neuroscience and Medicine in Jülich, Germany, studied the effects of ar-turmerone on NSC proliferation and differentiation both in vitro and in vivo. Rat fetal NSC were cultured and grown in six different concentrations of ar-turmerone over a 72 hour period. At certain concentrations, ar-turmerone was shown to increase NSC proliferation by up to 80%, without having any impact on cell death. The cell differentiation process also accelerated in ar-turmerone-treated cells compared to untreated control cells. 
Lead author of the study, Adele Rueger, said: “While several substances have been described to promote stem cell proliferation in the brain, fewer drugs additionally promote the differentiation of stem cells into neurons, which constitutes a major goal in regenerative medicine. Our findings on aromatic turmerone take us one step closer to achieving this goal.” 
Ar-turmerone is the lesser-studied of two major bioactive compounds found in turmeric. The other compound is curcumin, which is well known for its anti-inflammatory and neuroprotective properties. 
Study finds mind-body practices lower blood sugar levels in people with type 2 diabetes
University of Southern California School of Medicine, September 30, 2022
Mind-body practices such as yoga and meditation are increasingly popular tools for promoting health and combating diseases, including type 2 diabetes. Approximately 66% of Americans with type 2 diabetes use mind-body practices and many do so because they believe it helps control their blood sugar. Until now, however, whether mind-practices can reduce blood glucose levels has never been rigorously quantified.
According to new research conducted by a team from the Keck School of Medicine of USC, published in the Journal of Integrative and Complementary Medicine, some mind-body practices can be nearly as effective as commonly prescribed drugs at reducing blood glucose levels in people with type 2 diabetes. 
The team analyzed data from randomized controlled trials conducted across the globe between 1993 and 2022. They found 28 trials in which people with type 2 diabetes began a mind-body practice in addition to receiving medication and compared their results with people who only received medication to reduce their blood sugar levels.
This study, the first to analyze a range of mind-body practices including meditation, qigong, yoga and mindfulness-based stress reduction and their effect on blood glucose levels, revealed that all mind-body practices led to significant reductions in blood sugar levels. 
Taken as a whole, the mind-body practices averaged a .84% reduction in hemoglobin A1c, a measure of the average blood glucose level for the past 3 months. Yoga, the most-studied modality, provided the largest benefit, about a 1% reduction in hemoglobin A1c. The authors noted that a 1% reduction is particularly notable because metformin, the most prescribed diabetes drug, reduces hemoglobin A1c in people with type 2 diabetes by 1.1% on average. 
The research suggests that mind-body practices could be used as a both as a complementary nonpharmacological treatment for people with type 2 diabetes and possibly as a preventive measure as well. 
 Compound in Celery Found to Destroy 86% of Lung Cancer CellsGuangdong Pharmaceutical University (China),   September 28th, 2022Celery ihas been found to be extremely effective at killing ovarian, pancreatic, prostate, breast, liver, and lung cancer cells. In fact, in a recent study, celery killed up to 86% of cancer cells in the lungs (in vitro).In addition to calming your nervous system, aiding digestion, reducing inflammation, and lowering blood pressure, celery also contains an anti-cancer compound called apigenin, which has been effective at causing apoptosis (cell suicide) in numerous types of cancer cells.Researchers in China have found that by eating just two medium stalks of celery 2 to 3 times a week can reduce the risk of getting lung cancer by 60%. It is still not definitive through the scientists research, however, if the apigenin alone does the work of killing cancerous cells or if they work in cooperation with other compounds found in celeryFurthering the link, other research found: “Apigenin widely inhibits cell proliferation of various lung cancer cell lines in a dose-dependent manner and the combination treatment of apigenin and antitumor drugs is very effective in human lung cancer cells, and Nrf2-ARE pathway may contribute to the mechanism.”And another study’s abstract focusing on the broader impact of fruit and vegetable intake on cancer concluded:“In particular, high intake of Chinese cabbage (OR = 0.53), chives (OR = 0 .54), carrots (OR = 0.51) and celery (OR = 0.40) was inversely associated with lung cancer. The OR was more than six-fold elevated for smokers reporting low intake of vegetables, and more than four-fold elevated for smokers reporting low intake of fruit, as compared with never smokers reporting high intake of these items.  Moderate alcohol use linked to heart chamber damage, atrial fibrillation in new studyUniversity of California, San Francisco September 28, 2022  A study by UC San Francisco researchers found that even moderate alcohol consumption may change the structure of the heart in ways that increase the risk of atrial fibrillation.“There’s growing evidence that moderate alcohol intake may be a risk factor for atrial fibrillation, the most common heart rhythm disturbance in the world, but the mechanism by which alcohol may lead to atrial fibrillation is unknown,” said Gregory Marcus, MD, endowed professor of atrial fibrillation research at UCSF and senior author of the study published in the Journal of the American Heart Association.Marcus and colleagues looked at damage to the left atrium of the heart as a possible pathway between alcohol and atrial fibrillation. Atrial fibrillation is a known risk factor for stroke. The irregular pumping of blood can lead to blood clots, which may travel to the brain and cause stroke.The researchers evaluated data from more than 5,000 adults collected over several years in the Framingham Heart Study, including echocardiograms, medical history and self-reported alcohol intake. The study participants, mostly white and in their 40s to 60s, reported on average just over one drink per day. The overall rate of atrial fibrillation in the group was 8.4 cases per 1,000 people per year – meaning over a 10-year period, eight out of 100 people were likely to develop atrial fibrillation.Every additional drink per day was associated with a 5 percent increase in the yearly risk. Every additional drink per day also was associated with a statistically significant 0.16 millimeter enlargement of the left atrium, highlighting a possible site of physical damage caused by drinking  
Ginger effective for muscle pain relief
University of Georgia,  Sep 29, 2022
A new study has suggested that daily doses of raw or heat-treated ginger are effective for relieving muscle pain following strenuous exercise. 
Some research has shown that ginger may have anti-inflammatory and analgesic properties similar to nonsteroidal anti-inflammatory drugs.  In one study, four to 36 weeks of daily ginger doses (30 to 500 mg.) achieved reductions in knee pain from osteoarthritis. 
Researchers from the University of Georgia examined the efficacy of multiple days of ginger doses for relieving experimentally induced muscle pain from 18 eccentric muscle exercises. 
For the study, student volunteers were tested on 11 consecutive days while taking ginger supplements. Seventy-four students were divided in three groups given either raw ginger, heated ginger or placebo. 
The authors hypothesized that pain ratings after exercise would be lower in the ginger group compared to placebo subjects. 
Results from the subjects’ responses data showed that both raw and heat-treated ginger lowered muscle pain intensity after eccentric exercise by 25 and 23 per cent, respectively.  Heat treating ginger, therefore, did not increase the analgesic benefit.  
Whether ground, instant or decaffeinated, coffee drinking associated with longer life
Baker Heart and Diabetes Research Institute (Australia), September 28 2022. 
Regardless of the type of coffee consumed, people who drink coffee may live longer, as indicated by research findings reported in the European Journal of Preventive Cardiology.
“In this large, observational study, ground, instant and decaffeinated coffee were associated with equivalent reductions in the incidence of cardiovascular disease and death from cardiovascular disease or any cause,” senior author Peter Kistler, PhD, stated. 
The study included 449,563 men and women enrolled in the UK Biobank, which recruited UK residents from 2006 to 2010 and collected data concerning dietary intake, including coffee consumed, and other factors. Individuals included in the current investigation did not have cardiovascular disease or heart arrhythmias at the beginning of the study. 
During an average follow-up of 12.5 years, 27,809 deaths occurred. Compared with non-coffee drinkers, people who reported drinking ground, instant or decaffeinated coffee had a significantly lower risk of dying from all causes during follow-up. The greatest risk reduction was associated with drinking 2 to 3 cups coffee per day, with ground coffee associated with 27% lower risk compared with no coffee drinking. Drinking any type of coffee was also associated with a reduced chance of developing cardiovascular disease, and 2 to 3 cups was again associated with the most protection. The development of arrhythmias was less among people who consumed ground or instant coffee, but not decaffeinated coffee. 
“The beverage contains more than 100 biologically active components,” Dr Kistler remarked. “It is likely that the non-caffeinated compounds were responsible for the positive relationships observed between coffee drinking, cardiovascular disease and survival. Our findings indicate that drinking modest amounts of coffee of all types should not be discouraged but can be enjoyed as a heart healthy behavior.”

The Gary Null Show - 09.30.22

Videos:
Dr. Aseem Malhotra who promoted COVID-19 vaccine on TV calls for its immediate suspension (star: 0:12)
Dr. Robert Malone: ‘Monopolist’ Bill Gates has his ‘tentacles’ everywhere (22:00)
‘I Don’t Want That Pipeline Operational’: GOP Sen. Presses Witness On Nord Stream 2 (2:30-4:10)
My Unbelievable Interview with Biden!
Can Cabbage Beat Chemo for Cervical Cancer?South Dakota State University, September 26, 2022In a study published in the journal Cancer, UCLA researchers showed that radiation actually makes breast cancer cells MORE malignant. They found that radiation kills about half of the tumor cells treated.
But radiation also transforms other cells into “induced breast cancer stem cells.” Though cancer stem cells make up less than 5 percent of a tumor, they can regenerate the original tumor. In fact, these new stem cells are up to 30 times more likely to form tumors compared to cancer cells that didn’t get radiation. CSCs can also migrate through blood vessels spreading cancer to secondary locations.
Chemo works the same way.
Researchers from South Dakota State University have found that a compound in cruciferous vegetables like broccoli, cabbage, and cauliflower may target those cancer stem cells. In fact, it may help prevent the recurrence and spread of some cancers.
The compound is called phenethyl isothiocyanate (PEITC). When the researchers added PEITC to a Petri dish with human cervical cancer stem cells about 75 percent of the stem cells died within 24 hours.
The South Dakota researchers found that PEITC slowed the formation of cervical cancer stem cells in a dose-dependent manner. The researchers also found that PEITC significantly reduced the proliferation of both cervical cancer cells and stem cells. In fact, it worked comparably to salinomycin, a chemo drug, but without the toxic side effects.
In addition, the effects of PEITC were significantly better in abrogating cervical cancer stem cell proliferation than paclitaxel, another toxic chemo drug.
More physical activity, less screen time linked to better executive function in toddlers, study findsUniversity of Illinois at Urbana, September 29, 2022
A new study explored whether adherence to American Academy of Pediatrics guidelines for diet and physical activity had any relationship with toddlers’ ability to remember, plan, pay attention, shift between tasks and regulate their own thoughts and behavior, a suite of skills known as executive function.
Reported in The Journal of Pediatrics, the study found that 24-month-old children who spent less than 60 minutes looking at screens each day and those who engaged in daily physical activity had better executive function than those who didn’t meet the guidelines.
“Executive function underlies your ability to engage in goal-directed behaviors,” said University of Illinois Urbana-Champaign professor Naiman Khan,. “It includes abilities such as inhibitory control, which allows you to regulate your thoughts, emotions and behavior; working memory, by which you are able to hold information in mind long enough to accomplish a task; and cognitive flexibility, the adeptness with which you switch your attention between tasks or competing demands.”
Through its Bright Futures initiative, the AAP recommends that children spend less than 60 minutes looking at screens each day, engage in at least 60 minutes of physical activity, consume five or more servings of fruits and vegetables and minimize or eliminate the consumption of sugar-sweetened beverages.
“We found that toddlers who engaged in less than 60 minutes of screen time per day had significantly greater ability to actively control their own cognition than those who spent more time staring at phones, tablets, televisions and computers,” McMath said. “They had greater inhibitory control, working memory and overall executive function.”
Toddlers who got daily physical activity also did significantly better on tests of working memory than those who didn’t, the researchers found.
How rosemary essential oil can improve memory by 75 percentNorthumbria University (UK),
In a British study, researchers found that sniffing the essential oil of rosemary improved memory by a remarkable 75 percent – making it a possible treatment for memory problems.
The study, conducted by psychologists at Northumbria University in Newcastle, involved 66 people. Some were exposed to a rosemary-scented room, in which four drops of essential oil had been placed on an aroma stream diffuser and switched on for five minutes before the participants entered the room. Another group worked in an unscented room.
The psychologists found that the participants in the rosemary-scented room performed between 60 and 75 percent better on assorted memory tasks and on performing simple arithmetic when compared to the control group – an impressive result. As part of the study, researchers took blood samples to detect levels of 1,8-cineole – the constituent in rosemary linked with improving memory function. Participants in the rosemary room had higher levels of cineole – demonstrating that the compound can enter the bloodstream by way of inhalation.
In their findings, the team concluded that rosemary could have implications for treating memory impairments, especially in older adults who are experiencing some decline. Rosemary seems to be particularly helpful in promoting “prospective memory” – helping people to remember future events such as appointments or medication schedules.
Other studies have supported the ability of rosemary to both promote concentration and enhance memory of past events. Scientifically known as Rosmarinus officinalis, rosemary has long been used by natural healers to boost the immune system, reduce inflammation, fight pathogens and promote healthy digestion. The antioxidant value, or ORAC score, of rosemary is a massive 3,300, giving it the same potent free radical-fighting power of goji berries. Rosemary is rich in carnosic acid, an antioxidant that fights oxidative stress in the brain. Another rosemary constituent, carnosol, is strongly antioxidant and anti-inflammatory as well.
Study confirms energy transfer in different types of energy healing, including Reiki and acupunctureHolistic Research Institute (Knoxville TN), September 25, 2022
For many people, the benefits of energy healing practices like Reiki are immeasurable. But in a recent study, scientists attempted to do just that: Measure (and confirm) the energy transfer which takes place during a typical Reiki session. Reiki is an ancient practice of energy healing that first rose to fame in Japan during the 1800’s — but different takes on energy healing have existed for centuries. Now, scientists seek to confirm what the healers of the past already knew.
Reiki advocates say that the practice keys in on the flow of universal energy and that Reiki practitioners can transfer energy to their patients by channeling it through their hands. MedicalNewsToday.com reports that at least 60 hospitals in the United States offer Reiki therapy to their patients. Survey data suggests that over a million people will try Reiki or a similar therapy in a given year. Despite the naysayers in “modern” medicine, Reiki continues to grow in popularity.
Maria Kuman, Ph.D. at the Holistic Research Institute in Knoxville, Tennessee, conducted a study to analyze the potential energy transfers that occur during a Reiki healing session. Kuman herself admits that she was more than skeptical at the notion of real energy transfers taking place. To conduct her research, Kuman created patented highly sensitive equipment in order to measure the energy of Reiki practitioners and their patients during practice.
Kuman reports that their results showed that Reiki healers do not lose their own energy while healing. In fact, her equipment showed that there was an increase in energy for the healers, as well as their patients. “This proved the Reiki Masters right when claiming that by healing others they heal themselves,” she notes.
She explained further, “There could be only one explanation to this – the Reiki healers are not using their own body energy to heal. The fact that their energies have increased after healing and their energetic balance has improved means that there is a third source of energy, from which they draw. ”
To that end, Kuman contends that energy healing could be especially useful for disease prevention, by addressing energy imbalances before they lead to illness. Kuman also notes that the practice of acupuncture may offer similar benefits to Reiki, particularly regarding disease prevention.
Low-calorie sugar substitute consumption during adolescence appears to impair memory later in lifeUniversity of Southern California, September 29, 2022
A high-sugar diet early in life has been shown to harm brain function, but what about low-calorie sugar substitutes? A new study reveals they may take a heavy toll on the developing brain and gut.
In a study published in the journal JCI Insight, scientists at USC show that adolescent rats that consumed the low-calorie sweetenerssaccharin, ACE-K and stevia exhibited long-term impairments in memory.
The findings align with those from earlier studies in which the researchers show that adolescent rats that consume sugar suffer lingering memory impairment.Consuming low-calorie sweeteners also affected metabolic signaling in the body, which can lead to diabetes and other metabolism-related diseases.Rats that consumed low-calorie sweeteners as adolescents were less willing to work for sugar as adults, but they consumed more sugar if it was freely available, another factor that might affect the likelihood of developing metabolic disease.While most studies of low-calorie sweeteners focus on one substance and use amounts far exceeding the norm, the researchers made sure the study was in line with real-life conditions for people — Sweeteners tested include saccharin, acesulfame potassium (ACE-K) and stevia—which are commonly used in sweetened foods.
In the end, rats consuming sweetener were less likely to remember an object or the path through the maze than those that drank only plain water.
The scientists also found other effects among the rats after they consumed sweeteners.
They had fewer receptors on their tongues that detect sweet taste.The biological mechanism in their intestines that transports glucose into the blood was altered.Their brains had changed, specifically in regions associated with memory control and reward-motivated behavior.
Study finds folic acid treatment is associated with decreased risk of suicide attemptsUniversity of Chicago, September 28, 2022
Suicide is one of the leading causes of death in the US, with more than 45,000 people dying by suicide in 2020.
The study, published in JAMA Psychiatry used data from the health insurance claims of 866,586 patients and looked at the relationship between folic acidtreatment and suicide attempts over a two-year period. They found that patients who filled prescriptions for folic acid, also known as vitamin B9, experienced a 44% reduction in suicidal events (suicide attempts and intentional self-harm).
Gibbons initially became interested in folic acid in the context of suicide because of a previous study in which his group looked for relationships between risk of attempting suicide and 922 different prescribed drugs. The study simultaneously screened each drug for associations with increases and decreases in suicide attempts. Surprisingly, folic acid was associated with a decreased risk of suicide attempt, along with drugs expected to be associated with risk of suicide, like antidepressants, anxiolytics, and antipsychotics.
To investigate and further confirm the relationship between folic acid and suicide risk, Gibbons and his co-authors did this new study and focused specifically on folic acid, and accounted for many possible confounding factors, including age, sex, mental health diagnoses, other central nervous system drugs, conditions that affect folic acid metabolism, and more.
They even found that the longer a person took folic acid, the lower their risk of suicide attempt tended to be. Each month of being prescribed folic acid was associated with an additional 5% decrease in risk of suicide attempt during the 24-month follow-up period of their study.
If their findings are confirmed in the new research, folic acid would be a safe, inexpensive, and widely available suicide prevention strategy, and potentially help save thousands of lives.

The Gary Null Show - 09.29.22

Videos:
Dr. Mike Yeadon and Paul Alexander: fraud of the COVID pandemic
Prof. Boghossian: How to Combat Wokeism
My Unbelievable Interview with Biden!

The Gary Null Show - 09.28.22

video:
https://app.air.inc/a/cW1vAB3wp?ts=0
The Dark Truth of America’s Federation Of State Medical Boards (start @ 3:44)
Black gold? Rhizome extract said to have anti-ageing and anti-diabetic effectsOryza Chemical (Thailand),Black ginger extract could have important implications for healthy ageing and diabetes, as well as athletic performance.
Presented in Bangkok by Oryza Oil & Fat Chemical’s Masami Kawaziri, the herbaceous plant is also called black turmeric in Japan, and krachai dum in its country of origin, Thailand.
The plant’s extract has been used in Thailand for many years as a traditional medicine to boost energy and relieve gastrointestinal problems, and more recently, researchers in Asia have been looking into its benefits for seniors, diabetics and sportspersons.
Energising resultsIts polymethoxyflavones are said to enhance energy production, thereby improving glucose, fat and lipid metabolism. This can either prevent metabolic syndrome, or aid in treating diabetes.
The boost in energy production also helps to enhance athletic performance and recovery.
Kawaziri shared the results of a 2016 study on the effects of black ginger extract intake on physical strength, skin condition, post-exercise fatigue, and general fatigue.
Subjects who had been given the extract reported an increase in strength, and being less fatigued overall and after exercise.
Brains and brawnKawaziri said this was important for the elderly as well, since the extract is believed to minimise muscle loss. He added that the extract could play a part in “preventing poor blood circulation” and lowering blood pressure.
Furthermore, he said the extract could help to enhance and maintain cognitive function, delaying or perhaps even preventing diseases like Alzheimer’s.
Higher levels of fluoride in pregnant woman linked to lower intelligence in their childrenUniversity of Toronto
Fluoride in the urine of pregnant women shows a correlation with lower measures of intelligence in their children, according to University of Toronto researchers who conducted the first study of its kind and size to examine fluoride exposure and multiple states of neurodevelopment.
“Our study shows that the growing fetal nervous system may be adversely affected by higher levels of fluoride exposure,” said Dr. Howard Hu, the study’s principal investigator and professor of environmental health, epidemiology and global health at the Dalla Lana School of Public Health. “It also suggests that the prenatal nervous system may be more sensitive to fluoride compared to that of school-aged children.”
Tap water and dental products have been fluoridated in communities in Canada and the United States (as well as milk and table salt in some other countries) by varying amounts for more than 60 years to prevent cavities and improve bone health. In recent years, fierce debate over the safety of water fluoridation – particularly for children’s developing brains – has fuelled researchers to explore the issue and provide evidence to inform national drinking water standards.
There are some known side effects of fluoride. For example, dental defects like mild staining are common among those ingesting recommended levels of fluoride in the United States and Canada. Skeletal fluorosis – excessive accumulation of fluoride in the bones – is much less common and only observed at levels of fluoride in the water that are more than five to 10 times higher than those recommended.
“Relatively little is known, with confidence, about fluoride’s impact on neurodevelopment,” said Hu, whose research team included experts from U of T, National Institute of Public Health of Mexico, University of Michigan, McGill University, Indiana University, Mount Sinai School of Medicine and Harvard School of Public Health.
The study, “Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6-12 Years of Age in Mexico,” published today in Environmental Health Perspectives, analyzed data from 287 mother-child pairs in Mexico City that were part of the Early Life Exposures in Mexico to Environmental Toxicants (ELEMENT) project, which recruited pregnant women from 1994 to 2005 and has continued to follow the women and their children ever since.
The research team analyzed urine samples that had been taken from mothers during pregnancy and from their children between six and 12 years of age to reconstruct personal measures of fluoride exposure for both mother and child.
“This is significant because previous studies estimated exposures based on neighbourhood measurements of drinking water fluoride levels, which are indirect and much less precise measures of exposure. They also looked at children’s exposures instead of prenatal exposures or had much smaller sample sizes of subjects to study,” said Dr. Hu.
The researchers then analyzed how levels of fluoride in urine related to the children’s verbal, perceptual-performance, quantitative, memory, and motor abilities at age four and once more between the ages of six and 12. Analyses were adjusted for other factors known to impact neurodevelopment, such as gestational age at birth, birthweight, birth order, sex, maternal marital status, smoking history, age at delivery, IQ, education, socioeconomic status and lead exposure.
With regard to the study’s implications for populations in North America, researchers found that urinary fluoride levels in pregnant women were somewhat higher than, but within the general range of, urinary fluoride levels seen in non-pregnant general populations in Canada and the United States. However, in Dr. Hu’s opinion, the findings do not provide enough information to suggest there is no safe level of fluoride exposure.
“The potential risks associated with fluoride should be further studied, particularly among vulnerable populations such as pregnant women and children, and more research on fluoride’s impact on the developing brain is clearly needed.”
Polyphenol blend may boost post-exercise recovery: RCTUniversity of Murcia (Spain), and the University of Montpellier (France)Daily supplementation with a blend of extracts from mangosteen, elderberry, and pomegranate may delay muscle soreness and help manage post-exercise recovery, says a new study.
Consumption of Fytexia’s polyphenol-rich ingredient branded TensLess was associated with a 28% reduction in the perception of delayed onset muscle soreness (DOMS), compared with a placebo group, according to results of a randomized, placebo-controlled, crossover study.
Biomarkers of muscle damage were also reduced, in correlation with the decreases in DOMS, reported scientists from Fytexia (France), Catholic University of Murcia (Spain), and the University of Montpellier (France) in the journal Phytotherapy Research .
“This prospective study highlights the beneficial, both acute and sub-chronic effects of the supplementation with TensLess, a polyphenol-rich extract-based food supplement, on adverse symptoms associated with DOMS, namely eccentric exercise-related markers of muscle impairment,” they wrote.
Study detailsThe researchers recruited 13 recreationally active athletes (men and women) to participate in their study. Participants were randomly assigned to consume placebo or 1.5 grams per day of TensLess, composed of polyphenol-rich extracts from mangosteen (Garcinia mangostana L.), pomegranate (Punica granatum L.), and black elderberry (Sambucus nigra L.) combination for five days. All of the study participants performed an eccentric exercise protocol on day one of the study, and DOMS and biomarkers of muscle damage were monitored for four more days. This was then followed by a three-week “washout” period before they were crossed over to the other group for five more days.
The results showed that TensLess supplementation provided a significant 33% decrease in DOMS perception as early as the first 24 hours following physical exercise, compared to placebo. In addition to this acute benefit, a 28% reduction in DOMS perception was reported compared to the placebo group for the full duration of the study.
These effects were correlated with a lower levels of muscle damage-associated biomarkers, specifically creatine kinase, creatinine and myoglobin during the 4 days post-workout, added the researchers.
Taken together, these positive results clearly indicate that post-exercise supplementation with TensLess may preserve myocytes and reduce soreness following eccentric exercise-induced damages, and, accordingly, significantly shorten muscle recovery.
Study supports efficacy of hyaluronan for wrinkle reductionToho University Ohashi Medical Center (Japan)Twelve weeks of supplementation with hyaluronan – also known as hyaluronic acid – may improve the “luster” of the skin and reduce wrinkles, says a new study from Japan.
Data from a randomized, double-blind, placebo-controlled trial with 60 adults indicated that 120 milligrams per day of Kewpie’s hyaluronan ingredients Hyabest (A) and Hyabest (S) LF-P also led to improvements in skin suppleness.
“This study showed that the oral ingestion of the [molecular weight] 2 k or 300 k [hyaluronic acid] for 12 weeks suppresses wrinkles and improves the skin’s luster and suppleness in people aged 59 years or less who were healthy Japanese men and women over 22 years old. From the above, [hyaluronic acid] consumption is expected to be used as a method to maintain healthy skin,” wrote researchers from Kewpie Corporation and the Toho University Ohashi Medical Center in Clinical, Cosmetic and Investigational Dermatology .
Kewpie Corp funded the study.
HA and skinThe skin contains about 50% of the body’s hyaluronan (HA), a component present in every connective tissue. Degradation of HA and collagen is reported to be a cause of wrinkles, with many ingredient suppliers exploring the potential of supplementation to improve skin health from within.
Scientists from Kewpie authored a review i published in the Nutrition Journal, which concluded: “The reduction of HA in the skin by intrinsic and extrinsic factors such as aging and ultraviolet radiation, smoking and air pollutants induce dryness in the skin. However, daily HA supplements can moisturize the skin because the metabolites of HA increases the skin moisture content by having an effect on the skin cells. Thus, consuming HA affects skin cell and improves dry skin physiologically.
“This review shows that consuming HA moisturizes the skin and employing HA as a dietary supplement makes the skin healthy. We believe that countries worldwide will benefit from this review and consume HA to alleviate dry skin.”
The new double-blinded, placebo-controlled study adds to this body of evidence and investigated the effects of the ingredient on wrinkles.
The researchers recruited 60 Japanese men and women aged between 22 and 59 to participate in their study. The participants were randomly assigned to one of three groups: Placebo, or a HA formulation using one of two varieties, with a molecular weight of 2k or 300k (Hyabest (A) and Hyabest (S) LF-P, respectively). Both groups received a dosage of 120 mg per day.
Three-dimensional analysis of their skin indicated that the HA groups showed a better level of the whole sulcus (grooves in the skin) to volume ratio, wrinkle area ratio, and wrinkle volume ratio, compared to placebo and baseline values. However, only the 300 k (Hyabest (S) LF-P) group showed significantly diminished wrinkles compared with the placebo group.
Exercise can make cells healthier, promoting longer life, study findsUniversity of Virginia
Whether it’s running, walking, cycling, swimming or rowing, it’s been well-known since ancient times that doing some form of aerobic exercise is essential to good health and well-being. You can lose weight, sleep better, fight stress and high blood pressure, improve your mood, plus strengthen bones and muscles.
“Whether muscle is healthy or not really determines whether the entire body is healthy or not,” said Zhen Yan of the University of Virginia School of Medicine. “And exercise capacity, mainly determined by muscle size and function, is the best predictor of mortality in the general population.”
Yan and colleagues have completed a study in mice that, for the first time, shows that just one bout of moderate-to-intense exercise acts as a “stress test” on mitochondria in muscles. They discovered that this “stress test” induced by aerobic exercise triggers a process called mitophagy, where the muscle disposes of the damaged or dysfunctional mitochondria, making the muscle healthier. Yan compares exercise-induced mitophagy to a state vehicle inspection that removes damaged cars from the streets.
“Aerobic exercise removes damaged mitochondria in skeletal muscle,” Yan said. “If you do it repeatedly, you keep removing the damaged ones. You have a better muscle with better mitochondrial quality. We clean up the clunkers, now the city, the cell, is full of healthy, functional cars.”
How Exercise Removes Mitochondria ‘Clunkers’
For this study, Yan and colleagues assessed the skeletal muscle of a mouse model where they had added a mitochondrial reporter gene called “pMitoTimer.” The mitochondria fluoresce green when they are healthy and turn red when damaged and broken down by the cell’s waste-disposal system, the lysosomes.
The mice ran on a small treadmill for 90 minutes and Yan’s team observed mitochondrial stress (signs of “state inspection”) and some mitophagy (towing of the clunkers) at six hours after exercise. Yan explained that exercise in these mice also stimulated a kinase called AMPK, which in turn switched on another kinase, Ulk1. These chemical reactions appear to be important in control of the removal of dysfunctional mitochondria.
“When its turned on, Ulk1 activates other components in the cell to execute the removal of dysfunctional mitochondria,” Yan said. “It’s analogous to a 911 call where a tow truck removes the clunkers. However, we still do not know how these activities are coordinated.”
LED lights safer, more effective in producing Vitamin D3 than sunlightBoston University
Research published in Scientific Reports showsthat light from RayVio’s 293nm ultraviolet (UV) LED is more efficient than sunlight at producing vitamin D3 in skin samples. Tyler Kalajian and his research team, led by Dr. Michael F. Holick, Ph.D., M.D., and supported by Boston University School of Medicine and a Boston University Ignition Award, found that skin samples exposed to RayVio’s UV LED for just 0.52 minutes produced more than twice as much vitamin D3 as samples exposed to 32.5 minutes of sunlight.
“We tested ultraviolet LEDs from different sources and at different wavelengths. LED showed the most significantpotential for vitamin D3 production in the shortest amount of time,” said Dr. Holick, a Professor of Medicine, Physiology and Biophysics atBoston University School of Medicine, and endocrinologist at BostonMedical Center. “This study will lead to a new generation of technologythat can be labeled as photopharmacology in which the use of LEDswith targeted wavelengths can cause specific biologic effects in humanskin to help treat and prevent chronic illnesses.”
Vitamin D deficiency is associated with osteoporosis, rickets and other metabolic bone diseases and is more prevalent in northern and southern latitudes where sunlight is limited for a significant part of the year. This device for making vitamin D is ideally suited for patients with fat malabsorption syndromes including inflammatory bowel disease and gastric bypass surgery.
The research shows that LEDs could be used for treating patients that are vitamin D deficient. A vitamin D3 producing UV LED device could be used on skin areas that experience less exposure to sunlight such as upper legs and arms and abdomen and back thus minimizing risk for developing non-melanoma skin cancer. The UV LED device also emits a much narrower band of UVB light and thereby decreasing likelihood of skin damage that can occur when the skin is exposed to higher wavelengths of UV radiation.

The Gary Null Show - 09.27.22

Videos:
Gary Null – Speaks to U.N. on Earth Day (Part 1 & 2)
Iain McGilchrist, ‘We Need to Act’
Iain McGilchrist is a former Fellow of All Souls College, Oxford, an associate Fellow of Green Templeton College, Oxford, a Fellow of the Royal College of Psychiatrists, a Fellow of the Royal Society of Arts, a Consultant Emeritus of the Bethlem and Maudsley Hospital, London, a former research Fellow in Neuroimaging at Johns Hopkins University Medical School, Baltimore, and a former Fellow of the Institute of Advanced Studies in Stellenbosch. He now lives on the Isle of Skye, off the coast of North West Scotland, where he continues to write, and lectures worldwide.
 
California’s “holy herb” Yerba Santa found to be an effective natural treatment for Alzheimer’s  
Salk Institute for Biological Studies, September 19, 2022
Alzheimer’s disease is the most common form of dementia, and aging is its primary risk factor. Therefore, researchers continue to look for ways to counter the effects of aging on the brain. In a recent study, researchers from The Salk Institute for Biological Studies discovered a potential natural treatment for Alzheimer’s in the form of a medicinal herb found in California.
In their study published in the journal Redox Biology, they found that yerba santa (Eriodictyon californicum), a plant native to California, contains an active compound called sterubin that could be used to treat people with Alzheimer’s. Yerba santa, which is the Spanish for “holy herb,” is highly regarded as a medicine for respiratory diseases, bruising, fever, headaches, infections, and pain.
For the current study, the researchers first examined 400 plant extracts with known medicinal properties for their ability to prevent oxytosis – a type of cell death that occurs in Alzheimer’s disease – in mouse hippocampal nerve cells.
The researchers found that sterubin exhibited the greatest protective effect against inflammation and other triggers of brain cell death. In particular, sterubin strongly reduced inflammation in microglia, which are brain cells that provide support to nerve cells.
In addition, the researchers found that sterubin can remove iron from cells, helping to prevent iron accumulation. Iron accumulation can result in a type of nerve cell damage that accompanies aging and occurs in neurodegenerative problems.
“Not only did sterubin turn out to be much more active than the other flavonoids in Yerba santa in our assays, it appears as good as, if not better than, other flavonoids we have studied,” said Pamela Maher, the corresponding author of the study.
Vitamin B may reduce risk of stroke
Zhengzhou University (China)  September 23, 2022  
Researchers have uncovered evidence that suggests vitamin B supplements could help to reduce the risk of stroke, according to a study published in the journal Neurology.
Vitamin B supplements are said to be beneficial for many health issues, including stress, anxiety, depression, dementia, Alzheimer’s disease and heart disease.
However, according to Xu Yuming of Zhengzhou University in Zhengzhou, China, previous studies have conflicting findings regarding the use of vitamin B supplements and stroke or heart attack.
In order to determine the role of vitamin B supplements in the risk of stroke, Prof. Yuming and colleagues analyzed 14 randomized clinical trials involving a total of 54,913 participants  All studies compared use of vitamin B supplements with a placebo, or a very low dosage of the vitamin. All participants were then followed for a period of 6 months.
Results of the analysis revealed that the participants taking the vitamin B supplements had a 7% reduced risk of stroke, compared with those taking the placebo supplements or a low dosage of vitamin B.
The researchers found that a supplemental form of folate (vitamin B9) – a vitamin frequently found in fortified cereals – actually reduced the effect of vitamin B on the risk of stroke Additionally, the study showed that vitamin B12 did not have any effect on the risk of stroke. 
 Ginger may protect the brain from MSG toxicity, says fascinating research
University of Jeddah (Saudi Arabia), September 23, 2013 
For thousands of years, ginger has been hailed as a superfood for its healing properties that aid every system of the body. The oils that ginger contains are antibacterial, antiviral and antifungal, and ginger has even been found to inhibit cancer growth. Now a study has actually proven that ginger can reverse the damage done by monosodium glutamate, or MSG, a known harmful excitotoxin.
After injecting pure MSG into rats for 30 days, researchers found subsequent withdrawal caused adverse effects including significant epinephrine, norepinephine, dopamine and serotonin depletion. Low levels of these important neurotransmitters can be detrimental to health.
Subsequent to injecting lab rats with MSG, researchers injected ginger root extract for 30 more days and were able to completely reverse the neurotransmitter depletion and brain damage that MSG caused. Not only that, but the positive effects of ginger were maintained even after scientists stopped administering it!
A wealth of independent studies show that MSG should be avoided at all costs. Also popularly printed on food labels as hydrolyzed protein, torula or autolyzed yeast, soy or yeast extract and soy protein isolate among some 40 other names, scientists have found that consuming MSG even in low doses can cause blood glutamate levels to fluctuate abnormally high and then stay there. Anyone suffering from a disease or immunity issue that would contribute to a weakened blood-brain barrier is then much more susceptible to the chemical seeping into his or her brain and doing damage. Studies have effectively linked MSG consumption to several neurodegenerative diseases, such as Parkinson’s and Alzheimer’s.
Men with anxiety are more likely to die of cancer, study says
Cambridge University’s Institute of Public Health, September 20, 2022
Men over 40 who are plagued with generalized anxiety disorder are more than twice as likely to die of cancer than are men who do not have the mental affliction, new research finds. But for women who suffer from severe anxiety, the research found no increased risk of cancer death.
That finding, presented at the European College of Neuropsychopharmacology’s Congress in Vienna, emerges from the largest study ever to explore a link between anxiety and cancer. It tracked 15,938 Britons over 40 for 15 years.
Even after researchers took account of factors that boost the risk of cancer, including age, alcohol consumption, smoking and chronic diseases, men with a diagnosis of generalized anxiety disorder were 2.15 times as likely to die of cancer than were those with no such diagnosis.
Generalized anxiety disorder – a condition marked by excessive, uncontrollable worry about many areas of life – affected women more commonly than it did men. Among women in the large cohort studied, 2.4 percent suffered from the disorder. Among men in the cohort, 1.8 percent did.
Whatever the relationship, says the study’s lead author, the new findings identify extremely anxious men as a population whose mental and physical health should be closely tracked.
“Society may need to consider anxiety as a warning signal for poor health,” said study lead author Olivia Remes of Cambridge University’s Institute of Public Health. “With this study, we show that anxiety is more than just a personality trait,” but rather, a disorder linked to real and serious health risks.
Out of Over 400 Compounds Analyzed, Red Grapes and Blueberries Are Tops In Boosting Immunity – So Effective They Work As Well As DrugsLinus Pauling Institute at Oregon State University, September 18, 2022Pterostilbene, an antioxidant produced by plants has been shown to exhibit exceptional properties in fighting infections, cancer, hypertriglycerides, as well as the ability to reverse cognitive decline. It is believed that the compound also has anti-diabetic properties. In an analysis of 446 compounds for their the ability to boost the innate immune system in humans, researchers in the Linus Pauling Institute at Oregon State University discovered just two that stood out from the crowd. Red grapes and blueberies both have an exceptional ability to significantly impact immune function. In fact, pterostilbene works as well as some commercial drugs.

Both of these compounds, which are called stilbenoids, worked in synergy with vitamin D and had a significant impact in raising the expression of the human cathelicidin antimicrobial peptide, or CAMP gene, that is involved in immune function.The research was published in Molecular Nutrition and Food Research, in studies supported by the National Institutes of Health.

Almost a decade ago, researchers discovered that pterostilbene helps regulate blood sugar and might help fight type-2 diabetes. The finding adds to a growing list of reasons to eat colorful fruit, especially blueberries, which are rich in compounds known as antioxidants. These molecules battle cell and DNA damage involved in cancer, heart disease, diabetes and perhaps also brain degeneration. 

Pterostilbene works as well as the commercial drug ciprofibrate to lower the levels of fats (lipids) and triglycerides — but they worked even more accurately. They are so specific that side-effects are non-existent.”Out of a study of hundreds of compounds, just these two popped right out,” said Adrian Gombart, an LPI principal investigator and associate professor in the OSU College of Science. “Their synergy with vitamin D to increase CAMP gene expression was significant and intriguing. It’s a pretty interesting interaction.”This research is the first to show a clear synergy with vitamin D that increased CAMP expression by several times, scientists said.The CAMP gene itself is also the subject of much study, as it has been shown to play a key role in the “innate” immune system, or the body’s first line of defense and ability to combat bacterial infection. The innate immune response is especially important as many antibiotics increasingly lose their effectiveness.

Grapes don’t have to be fermented to contain this antioxidant. It’s actually found in the skin of red grapes along with other nutrients, such as minerals manganese and potassium and vitamins K, C and B1.Stilbenoids are compounds produced by plants to fight infections, and in human biology appear to affect some of the signaling pathways that allow vitamin D to do its job, researchers said. It appears that combining these compounds with vitamin D has considerably more biological impact than any of them would separately.
Fungus in humans identified for first time as key factor in Crohn’s disease
Case Western Reserve University, September 22, 2022
A Case Western Reserve University School of Medicine-led team of international researchers has for the first time identified a fungus as a key factor in the development of Crohn’s disease. The researchers also linked a new bacterium to the previous bacteria associated with Crohn’s. The groundbreaking findings, published in mBio, could lead to potential new treatments and ultimately, cures for the debilitating inflammatory bowel disease, which causes severe abdominal pain, diarrhea, weight loss, and fatigue.
Mycology at Case Western Reserve and University Hospitals Cleveland Medical Center “Essentially, patients with Crohn’s have abnormal immune responses to these bacteria, which inhabit the intestines of all people. While most researchers focus their investigations on these bacteria, few have examined the role of fungi, which are also present in everyone’s intestines. Our study adds significant new information to understanding why some people develop Crohn’s disease. Equally important, it can result in a new generation of treatments, including medications and probiotics, which hold the potential for making qualitative and quantitative differences in the lives of people suffering from Crohn’s.”
The researchers assessed the mycobiome and bacteriome of patients with Crohn’s disease and their Crohn’s-free first degree relatives in nine families in northern France and Belgium, and in Crohn’s-free individuals from four families living in the same geographic area. Specifically, they analyzed fecal samples of 20 Crohn’s and 28 Crohn’s-free patients from nine families and of 21 Crohn’s-free patients of four families. The researchers found strong fungal-bacterial interactions in those with Crohn’s disease: two bacteria (Escherichia coli and Serratia marcescens) and one fungus (Candida tropicalis) moved in lock step. The presence of all three in the sick family members was significantly higher compared to their healthy relatives, suggesting that the bacteria and fungus interact in the intestines. Additionally, test-tube research by the Ghannoum-led team found that the three work together (with the E. coli cells fusing to the fungal cells and S. marcescens forming a bridge connecting the microbes) to produce a biofilm — a thin, slimy layer of microorganisms found in the body that adheres to, among other sites, a portion of the intestines — which can prompt inflammation that results in the symptoms of Crohn’s disease.
This is first time any fungus has been linked to Crohn’s in humans; previously it was only found in mice with the disease. The study is also the first to include S. marcescens in the Crohn’s-linked bacteriome. Additionally, the researchers found that the presence of beneficial bacteria was significantly lower in the Crohn’s patients, corroborating previous research findings.

The Gary Null Show - 09.26.22

Videos :
Those who speak out are shouted down until they are proved right, says Neil Oliver – 10:06
Gad Saad: Why Rational People Fall for ‘Parasitic’ Ideas | American Thought Leaders CLIP – 9:11
Scientist Carl Sagan testifying to the U.S. Senate in 1985 on the greenhouse effect: – 2:44
Parent Eviscerates School Board Over Censorship– 4:59
Vitamin C supplementation associated with improved lung function in COPDMedical College of Lanzhou University (China), September 23 2022.
The International Journal of Chronic Obstructive Pulmonary Disease published a systematic review and meta-analysis of clinical trials that found improvement in lung function among chronic obstructive pulmonary disease (COPD) patients who received vitamin C. The disease is characterized by airflow limitation and persistent respiratory symptoms.
Ting Lei of Medical College of Lanzhou University in Lanzhou, China and associates identified 10 randomized, controlled trials that included a total of 487 adults with COPD for the meta-analysis. The trials compared lung function and/or antioxidant enzyme or nutrient levels of COPD patients who received vitamin C to a placebo or control group.
The meta-analysis found improvement in forced expiratory volume in one second as a percentage (FEV1%, a measure of lung function) in association with vitamin C supplementation. When dosage was analyzed, it was determined that consuming more than 400 milligrams vitamin C per day was needed experience a significant benefit.
The ratio of FEV1 to forced vital capacity (another lung function assessment), and levels of vitamin C and glutathione, both of which are antioxidants, also improved among participants who received vitamin C supplements. The authors remarked that oxidative stress, which is a disturbance of the oxidant to antioxidant balance, has been suggested as playing a role in the development of COPD.
The current investigation is the first systematic review and meta-analysis to assess the effect of vitamin C supplementation in people with COPD.
“We found that supplementing vitamin C to patients with COPD demonstrated vital clinical significance,” Lei and associates concluded. “Vitamin C supplementation could increase the levels of antioxidation in serum (vitamin C and glutathione) and improve lung function (FEV1% and FEV1/FVC), especially in patients treated with vitamin C supplementation greater than 400 mg/day.”
Single Flavanoid (Found in 6 Foods) Reduces Cognitive Impairment Drastically
Fourth Military Medical University (China), September 19, 2022
A singular flavanoid can protect the brain against cognitive deficit and other cellular damage, according to studies from the Fourth Military Medical University. The news comes from Xi’an, People’s Republic of China, and shows great promise for those suffering from mental impairment due to Alzheimer’s disease, vascular dementia, and other debilitating cognitive conditions.
The study abstract concludes:
“Our results provide new insights into the pharmacological actions of rutin and suggest that rutin has multi-targeted therapeutical potential on cognitive deficits associated with conditions with chronic cerebral hypoperfusion such as vascular dementia and Alzheimer’s disease.”
Rutin is a biologically active flavonoid found in the following foods:
 Buckwheat – Possibly the best source of rutin, and much better than boiled oats, uncooked buckwheat leaf flower offers about 675 mg in a 1.1 cup serving. Uncooked buckwheat groats contain 230 mg of rutin per 1 kg, dark buckwheat flour has 218 mg per 1 kg and buckwheat noodles provide 78 mg.
Elderflower Tea – When dried, the white flowers of the elderflower make a delicious and rutin-filled tea. According to the Czech Journal of Food Science, elderflower tea contains approximately 10.9g/kg of rutin per brewed cup.
Amaranth Leaves – In Western cultures, most people are familiar with the edible seeds of amaranth, though in Chinese and Southeast Asian cooking the leaves are also gaining traction, partly due to their high rutin content. You can expect around 24.5g/kg from the dried leaves. Seeds only contain trace amounts of the important nutrient.
Unpeeled Apples – Keep the peel on your apples to enjoy lots of rutin. Just be sure that they are organic, since apple peels are especially prone to pesticide build-up. Apple skins are 6x as powerful as the flesh at preventing high blood pressure due to this flavanoid, too.
• Unfermented Rooibos Tea – While rooibos tea contains fewer antioxidants than black or green teas, it is a good source of rutin, providing around 1.69 mg/g.
• Figs – These little gems contain about the same amount of rutin as apples, so be sure to add them to your diet.
The scientists found that rutin works primarily through anti-inflammatory mechanisms, and reducing hypofusion in the brain.
Resistance-breathing training found to lower blood pressureUniversity of Colorado and University of Arizona, September 23, 2022
A team of researchers with members from the University of Colorado, the University of Arizona and Alma College, has found that resistance-breathing training can lower blood pressure as much as some medicines and/or exercises. The study is published in the Journal of Applied Physiology.
Hypertension, also known as chronic high blood pressure, can lead to a wide variety of health problems, from loss of vision to strokes and heart attacks. For that reason, doctors take it seriously. Typically, patients are directed to modify their diet and to exercise more. If that does not fix the problem, medications are prescribed. In this new effort, the researchers looked into a new type of therapy to reduce blood pressure levels—resistance-breathing training.
Resistance-breathing training involves breathing in and out of a small device, called, quite naturally, a POWERbreathe, every day for several minutes. The device forces the patient to use their breathing muscles to push and pull air through it, making them stronger. And that, the researchers found, also reduces blood pressure. The device has been in use for several years as a means to assist athletes, singers and people with weak lung muscles.
Several groups of healthy volunteers practiced the training for a few minutes every day for six weeks. Each was breathed in and out with the device 30 times each session. Each of the volunteers had their blood pressure measured before and after the training.
The researchers found a sustained average drop of 9 mmHg in systolic blood pressure (the top number in blood pressure readings)—normal pressure is defined as 120/80. They describe the change as significant, as much as some patients see with medication. They also note that it is similar to changes in many patients who begin an aerobic exercise regimen, such as walking, cycling or running. They suggest such training could be used by patients of all ages who are unable to exercise to lower their blood pressure.
How To Maintain Peak Brain Health: Scientists Say It Comes Down To These 3 FactorsNorwegian University of Science and Technology, September 23, 2022
What’s the best way to maintain peak brain health as we age? There are countless studies detailing ways to prevent cognitive decline, so scientists in Norway sought to simplify the science of managing strong brain health to three recommendations.
This report is something of a summation covering modern science’s current understanding of how best to cultivate robust brain health. The team at NTNU cite 101 references to prior articles in this latest theoretical perspective paper.
“Three factors stand out if you want to keep your brain at its best,” Prof. Sigmundsson adds.
The three identified keys to strong brain health are:
Physical exerciseSocial activityStrong, passionate interests and hobbiesIt’s common knowledge that spending all day on the couch isn’t healthy for the body, but physical activity is also key to brain health. “An active lifestyle helps to develop the central nervous system and to counteract the aging of the brain,” according to study authors.
Researchers add that consistency is essential. Do your best to get in at least a little movement each and every day. Even if you work a sedentary job that requires lots of sitting, get moving every hour or so for just a few minutes at the very least.
Some people are naturally more social than others, but researchers stress that no one is an island. Even if you prefer a quiet night in to attending a party, make an effort to stay in touch with the people who matter to you. Our brains thrive on social interactions and connections.“Relationships with other people, and interacting with them, contribute to a number of complex biological factors that can prevent the brain from slowing down,” Prof. Sigmundsson explains.
Just like bicep curls help us build muscle, keeping the brain active promotes strong lifelong cognition. Consider taking up a new hobby, or learning a new skill. Perhaps most importantly, though, don’t force it; find something you’re actually passionate about. It’s never too late in life to learn something new!
“Passion, or having a strong interest in something, can be the decisive, driving factor that leads us to learn new things. Over time, this impacts the development and maintenance of our neural networks,” Prof. Sigmundsson says.
“Brain development is closely linked to lifestyle. Physical exercise, relationships and passion help to develop and maintain the basic structures of our brain as we get older,” Prof. Sigmundsson concludes.
Calcium supplements may support a healthy colon: Harvard study
Harvard School of Public Health, September 18, 2022
Supplements of calcium or non-dairy products fortified with the mineral may reduce the risk of colorectal cancer, according to meta-analysis of prospective observational studies by researchers at Harvard School of Public Health.
For every 300 mg increase in calcium from supplements was associated with a 9% reduction in risk, wrote NaNa Keum and her co-authors in the International Journal of Cancer .
Every 300 mg increase in total calcium was associated with a similar reduction in risk (8%), they added.
“Our findings have several important clinical and public health implications,” they explained. “First, according to the 2003 to 2006 National Health and Nutrition Examination Survey, a nationally representative cross-sectional survey in the U.S., median total calcium intake of adults aged over 50 years was approximately 650 mg/day for no calcium-supplement users and 1,000 mg/day for calcium-supplement users.
“As the benefit of calcium intake on CRC is expected to continue beyond 1,000 mg/day, not only non-supplement users but also supplement users may further reduce their CRC risk through additional calcium intake.”
“Second, while dairy products, especially milk, are the major sources of calcium in many countries, they are a substantial source of calories and contain potentially harmful factors such as saturated fat, hormones, and casein proteins. Since our analyses provide evidence for an equivalent benefit of dietary and supplementary calcium, the benefit of calcium on CRC risk may be obtained through supplements and non-dairy products fortified with calcium.”
The Boston-based scientists conducted dose-response meta-analyses of 15 studies involving 12,305 cases of colorectal cancer and calcium intakes ranging from 250-1,900 mg/day. The studies varied in duration from 3.3 to 16 years.
The data indicated that both total and supplemental calcium were associated with reductions in the risk of colorectal cancer.
“In conclusion, both dietary and supplementary calcium intake may continue to decrease colorectal cancer risk beyond 1,000 mg/day,” wrote Keum and her co-authors.
Yoga’s Age-Defying Effects Confirmed by ScienceDefence Institute of Physiology and Allied Sciences (India), September 21st 2022While yoga’s longevity promoting effects have been the subject of legend for millennia, increasingly modern science is confirming this ancient technology for spiritual and physical well-being actually can slow aging and stimulate our regenerative potential.
One particularly powerful study published lin the journal Age titled, “Age-related changes in cardiovascular system, autonomic functions, and levels of BDNF of healthy active males: role of yogic practice”, found that a brief yoga intervention (3 months) resulted in widespread improvements in cardiovascular and neurological function.
Indian researchers studied healthy active males of three age groups (20-29, 30-39, and 40-49 years) by randomly assigning them to practice one hour of yoga daily for 3 months.
The observed significant differences between the younger and older participants in the study, specifically: “Significantly higher values of heart rate (HR), blood pressure (BP), load in heart (DoP), myocardial oxygen consumption (RPP), and total cholesterol (TC) were noted in senior age group.” The yogic practice resulted in significant reductions in all of these parameters (HR, BP, DoP, RPP and TC).
Also observed in the older participants were decreases in high frequency (HF), total power (TP), all time domain variables of heart rate variability (HRV), and skin conductance (SC) — all of which increased following yogic practice.
Higher levels of catecholamines (“stress hormones”) and low frequency (LF) power of HRV were noted in advancement of age, both of which decreased following yogic practice.
Additionally, the senior age group had highest levels of cortisol and adrenocorticotrophic hormone (ACTH), both of which decreased following yogic practice.
Finally, brain-derived neurotropic factor (BDNF), serotonin, and dopamine were low in higher age group, but these increased following yogic practice; an indication of improved brain function and cognition.
The researchers concluded: ‘This study revealed that yogic practices might help in the prevention of age-related degeneration by changing cardiometabolic risk factors, autonomic function, and BDNF in healthy male.”
There are a number of promising studies revealing the age-defying potential of this ancient practice. Here are some additional benefits confirmed in 2014 alone:
Age-Related Respiratory Problems: A 2014 study from the journal of Human Kinetics found that a 3 month yoga intervention in 36 elderly women (average age 63.1) significantly improved pulmonary (respiratory) function.Age-Related Brain Cognitive Decline: A review in the Journals of Gerontology, involving a two month Hatha yoga intervention in the elderly (average age 62.0) resulted in significant improvements in “executive function measures of working memory capacity and efficiency of mental set shifting and flexibility compared with their stretching-strengthening counterparts.”Age-Related Hormone Insufficiency: A study published in Evidence Based Complementary and Alternative Medicine found that a 3 month yogic intervention in men (average age 42.8) and women (average age 44.75) resulted in improvements in the level of growth hormone and DHEAS, two essential hormones that drop off precipitously as we age.Age-Related Sleep Problems: Astudy published in Alternatives Therapies in Health and Medicine found a 12 week yogic intervention (yoga 2x a week) resulted in significant improvements in the quality of sleep in older individuals (average age 60).Age-Related Depression: From the Chinese Journal of Nursing found that not only did yoga improve sleep as found in the study above but also significantly reduced the depressive symptoms of elderly participants…after 6 months. “This is just a small sampling of the literature. There is older research revealing that yoga has even more benefits for aging populations.

The Gary Null Show - 09.23.22

Omega-3 and Omega-6 supplement improves reading for children
University of Gothenburg, Sweden - September 14, 2022
 
Supplement of omega-3 and omega-6 fatty acids may improve reading skills of mainstream schoolchildren, according to a new study from Sahlgrenska Academy, at the University of Gothenburg, Sweden. Children with attention problems, in particular, may be helped in their reading with the addition of these fatty acids.
 
The study included 154 schoolchildren from western Sweden in grade 3, between nine and ten years old. The children took a computer-based test (known as the Logos test) that measured their reading skills in a variety of ways, including reading speed, ability to read nonsense words and vocabulary.
 
The children were randomly assigned to receive either capsules with omega-3 and omega-6, or identical capsules that contained a placebo (palm oil) for 3 months. The children, parents and researchers did not learn until the study was completed which children had received fatty acids and which had received the placebo. After three months, all children received real omega-3/6 capsules for the final three months of the study.
 
"Even after three months, we could see that the children's reading skills improved with the addition of fatty acids, compared with those who received the placebo. This was particularly evident in the ability to read a nonsense word aloud and pronounce it correctly (phonologic decoding), and the ability to read a series of letters quickly (visual analysis time)," says Mats Johnson, who is chief physician and researcher at the Gillberg Neuropsychiatry Centre at Sahlgrenska Academy, University of Gothenburg.
 
No children diagnosed with ADHD were included in the study, but with the help of the children's parents, the researchers could identify children who had milder attention problems. These children attained even greater improvements in several tests, including faster reading already after three months of receiving fatty acid supplements.
 
 
Mango could help maintain gut bacteria at risk from high-fat dietsOklahoma State University, SEPTEMBER 21, 2022Mango consumption could help prevent the loss of beneficial gut bacteria caused by a high fat diet, according to research on mice.
The findings, published in the Journal of Nutrition , appears to reveal for the first time the positive impact of mango on gut microbiota.
In the study, 60 male mice were assigned to one of four dietary treatment groups for 12 weeks - control (with 10% of calories from fat), high fat (with 60% calories from fat), or high fat with 1% or 10% mango. All high-fat diets had similar macronutrient, calcium, phosphorus, and fiber content.
“We investigated the effects of freeze-dried mango pulp combined with an high-fat diet on the cecal microbial population and its relation to body composition, lipids, glucose parameters, short-chain fatty acid (SCFA) production, and gut inflammatory markers in a mouse model of diet-induced obesity,” the study reports.
The high-fat dietary treatment with 10% mango (equivalent to 1½ cups of fresh mango pieces) was found to be the most effective in preventing the loss of beneficial bacteria from a high-fat diet without decreasing body weight or fat accumulation.
Specifically, mango supplementation regulated gut bacteria in favor of Bifidobacteria and Akkermansia and enhanced short-chain fatty acid (SFCA) production. SCFAs have been shown to possess a wide range of beneficial effects, such as anti-inflammatory properties.
Yoga improves arthritis symptoms and mood, study finds Johns Hopkins School of Medicine,  September 15, 2022
A randomized trial of people with two common forms of arthritis has found that yoga can be safe and effective for people with arthritis. Johns Hopkins researchers report that 8 weeks of yoga classes improved the physical and mental wellbeing of people with two common forms of arthritis, knee osteoarthritis and rheumatoid arthritis. The study is believed to be the largest randomized trial so far to examine the effect of yoga on physical and psychological health and quality of life among people with arthritis.
The study recruited 75 people with either knee osteoarthritis or rheumatoid arthritis. Participants were randomly assigned to either a wait list or eight weeks of twice-weekly yoga classes, plus a weekly practice session at home. Participants' physical and mental wellbeing was assessed before and after the yoga session by researchers who did not know which group the participants had been assigned to.
Compared with the control group, those doing yoga reported a 20% improvement in pain, energy levels, mood and physical function, including their ability to complete physical tasks at work and home. Walking speed also improved to a smaller extent, though there was little difference between the groups in tests of balance and upper body strength. Improvements in those who completed yoga was still apparent nine months later.
 
Stevia Kills Lyme Disease Pathogen Better Than Antibiotics (Preclinical Study)University of New Haven, September 21, 2022
A promising new preclinical study has revealed that whole stevia leaf extract possesses exceptional antibiotic activity against the exceedingly difficult to treat pathogen Borrelia Burgdorferi known to cause Lyme disease. The study found,
"Stevia whole leaf extract, as an individual agent, was effective against all known morphological forms of B. burgdorferi."
At present, the CDC acknowledges that at least 300,000 are infected with Lyme disease, annually, with the conventional standard of care relying on antibiotics that are not only toxic but increasingly coming under scrutiny for addressing only surface aspects of the infection, often leaving antibiotic-resistance Lyme disease deep within the system to continue to cause harm. 
The new study was published in the European Journal of Microbiology & Immunology and conducted by researchers from the Department of Biology and Environmental Science, University of New Haven, West Haven, CT.
The researchers directly compared an alcohol extract of a whole stevia leaf product commonly found on the U.S. retail market to conventional antibiotics, and assessed their respective abilities to kill the various forms of Borrelia burgdorferi, including so called "persister" forms.
The researchers explored Stevia's potential effectiveness against B. burgdorferi cultures, comparing it to three common antibiotics sometimes used to treat Lyme's disease: doxycycline, cefoperazone, daptomycin, as well as their combination.
The study results were summarized as follows:     Our results demonstrated that Stevia had significant effect in eliminating B. burgdorferi spirochetes and persisters. Sub-culture experiments with Stevia and antibiotics treated cells were established for 7 and 14 days yielding, no and 10% viable cells, respectively compared to the above-mentioned antibiotics and antibiotic combination. When Stevia and the three antibiotics were tested against attached biofilms, Stevia significantly reduced B. burgdorferi forms. Results from this study suggest that a natural product such as Stevia leaf extract could be considered as an effective agent against B. burgdorferi."
Notably, the study found that the most antibiotic resistant form of B. burgdorferi, the biofilm form, actually increased in mass when individual antibiotics were administered. Stevia, on the other hand, reduced the biofilm mass on both tested surfaces (plastic and collagen) by about 40%.  
 
Green soy extract could prevent cognitive dysfunction: Mouse data
University of Shizuoka (Japan), September 19, 2022
 
Intake of green soybean extract could help reverse cognitive dysfunction and its associated accumulation of beta-amyloid proteins in the brain, say researchers.
 
The accumulation of beta-amyloid proteins has long been linked to the development of brain stunting conditions including Alzheimer’s disease and other forms of dementia. 
 
Writing in the Journal of Functional Foods, the team revealed that brain functions were ‘significantly better-preserved’ in aged mice fed green soybean than age-matched control mice with or without yellow soybean feeding.
 
An increased expression of lipocalin-type prostaglandin D2 synthase (Ptgds) and a significant reduction in the amyloid precursor protein Aplp1 was reported by the team, led by Keiko Unno from the University of Shizuoka in Japan.
 
“Furthermore, the amount of beta-amyloid 40 and 42 was reduced in the insoluble fraction of cerebral cortex,” the team noted.
 
In the current study, the isoflavones found to be present in soybean extracts were mostly the glycosides genstin and daidzin. Furthermore, the contents of saponin and carotene in green soybean were found to be slightly higher in the green than in yellow, however the contents of other components were not different between green and yellow soybeans.
 
 
 
JAMA study links low vitamin D levels to ‘profound’ and ‘rapid’ cognitive decline
Rutgers University & University of California Davis, September 15, 2022
Vitamin D deficiency and insufficiency may have “substantial” accelerating effects on cognitive decline in the elderly, says a new study from UC Davis and Rutgers University.
Low levels of the sunshine vitamin were associated with a three times faster rate of cognitive decline than those with adequate vitamin D levels, according to findings published in JAMA Neurology .
The low vitamin D levels were associated with impaired performance, particularly in domains such as memory loss that are associated with Alzheimer’s disease and dementia, added the researchers.
The researchers said their findings amplify the importance of identifying vitamin D insufficiency among the elderly, particularly high-risk groups such as African-Americans and Hispanics, who are less able to absorb the nutrient from its most plentiful source: sunshine. Among those groups and other darker-skinned individuals, low vitamin D should be considered a risk factor for dementia, they added.
Dr Miller and his co-workers analyzed data from 382 racially and ethnically diverse men and women (mean age of 76) in Northern California participating in longitudinal research at the Alzheimer’s Disease Center in Sacramento. Of the participants, 41% were white, 30% were African American, 25% were Hispanics, and 4% were from other racial/ethnic groups. The participants were either cognitively normal, or had mild cognitive impairment or dementia.
Baseline data showed that 26% of the participants were vitamin D deficient, while 35% were insufficient. Among Caucasians, 54% had low vitamin D, compared with 70% of African-Americans and Hispanics.
The rate of cognitive decline was found to be two-to-three times faster in the vitamin D deficient people over five years of study, compared to people with adequate serum vitamin D levels. In other words, it took only two years for the deficient individuals to decline as much as those with adequate vitamin D declined during the five-year follow-up period.

The Gary Null Show - 09.22.22

VIDEOS:
The elite that has taken almost all the money is now after everything else as well | Neil Oliver
The Metaverse Is Worse Than You Thought – by MOON
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Blackcurrant nectar shows exercise benefits for college students: Study
University of the Incarnate Word, September 14, 2022
Daily consumption of blackcurrant nectar for eight days may reduce muscle damage and inflammation after exercise, according to a new study from scientists at the University of the Incarnate Word in San Antonio, Texas.
Sixteen ounces per day of the blackcurrant nectar were associated with reductions in the activity of creatine kinase, a blood marker of muscle damage, by 6.7%, compared to 82% increases in activity in the placebo group 48 hours after exercise, report the researchers in the Journal of Dietary Supplements .
Researchers led by Alexander Hutchison, PhD, also report that levels of the inflammatory compound interleukin-6 decreased after exercise in participants in the blackcurrant group, compared with increases seen in the placebo group.
“In partial support of our primary hypotheses, we found that consumption of black currant nectar for four days before and three days after a bout of eccentric leg exercise significantly reduced circulating markers of muscle damage while maintaining circulating antioxidant capacity,” they wrote in their paper. “Although pain scores in the blackcurrant nectar group returned to baseline a day earlier than the placebo group, there were no significant differences observed between groups at any time point after exercise.
The study included 16 college students randomly assigned to consumer either the blackcurrant nectar beverage (CurrantC provided by CropPharms from Staatsburg, NY) or placebo twice a day for eight days. On day 4 the participants performed a bout of knee extension exercises, and blood samples taken 24, 48, and 96 hours after the exercise.
Results showed that ORAC levels in the blood significantly decreased in the placebo group, while no significant decreases from the baseline values were observed in the blackcurrant group. In addition, significant differences between the groups were observed for IL-6 levels 24 hours after exercise, while significant differences were observed in creatine kinase activity between the groups after 48 and 96 hours..
How does what we eat affect our health span and longevity? It’s a complex, dynamic systemColumbia University’s Mailman School of Public Health, September 21, 2022
How does what we eat affect how we age? The answer to this relatively concise question is unavoidably complex, according to a new study at the Butler Columbia Aging Center at Columbia University Mailman School of Public Health. The findings are published online in the journal BMC Biology.
While most analyses had been concerned with the effects of a single nutrient on a single outcome, a conventional, unidimensional approach to understanding the effects of diet on health and aging no longer provides us with the full picture: A healthy diet must be considered based on the balance of ensembles of nutrients, rather than by optimizing a series of nutrients one at a time. Until now little was known about how normal variation in dietary patterns in humans affects the aging process.
“”This study therefore provides further support to the importance of looking beyond ‘a single nutrient at a time’ as the one size fits all response to the age-old question of how to live a long and healthy life.” Cohen also points that the results are also concordant with numerous studies highlighting the need for increased protein intake in older people, in particular, to offset sarcopenia and decreased physical performance associated with aging.
The researchers analyzed data from 1,560 older men and women, aged 67-84 years selected randomly from the Montreal, Laval, or Sherbrooke areas in Quebec, Canada, who were re-examined annually for three years and followed over four years to assess on a large scale how nutrient intake associates with the aging process.
Aging and age-related loss of homeostasis (physiological dysregulation) were quantified via the integration of blood biomarkers. The effects of diet used the geometric framework for nutrition, applied to macronutrients and 19 micronutrients/nutrient subclasses. Researchers fitted a series of eight models exploring different nutritional predictors and adjusted for income, education level, age, physical activity, number of comorbidities, sex, and current smoking status.
Four broad patterns were observed:
The optimal level of nutrient intake was dependent on the aging metric used. Elevated protein intake improved/depressed some aging parameters, whereas elevated carbohydrate levels improved/depressed others;There were cases where intermediate levels of nutrients performed well for many outcomes (i.e. arguing against a simple more/less is better perspective);There is broad tolerance for nutrient intake patterns that don’t deviate too much from norms (“homeostatic plateaus”).Optimal levels of one nutrient often depend on levels of another (e.g. vitamin E and vitamin C). Simpler analytical approaches are insufficient to capture such associations.
Mediterranean diet could play a key role in preventing cognitive declineBrigham and Women’s Hospital and Harvard University, September 20, 2022
Individuals of minoritized ethnic or racial groups are often underrepresented in research, thus hindering the understanding of risk factors and the efficacy of treatments for diseases in these minoritized groups.
A recent study published in the journal Alzheimer’s & Dementia found that the levels of six plasma metabolites were associated with lower cognitive function across all racial/ethnic groups, and the levels of most of these blood metabolites were associated with adherence to a Mediterranean diet.
Speaking to Medical News Today, the study’s corresponding author Dr. Tamar Sofer, a professor at Brigham and Women’s Hospital at Harvard University, said:
“We identified a few metabolites (small molecules) in blood that their levels are correlated with cognitive function, and they are all related to diet.
Characterizing metabolites associated with cognitive function can help researchers understand the mechanisms underlying the development of dementia. Moreover, blood metabolites can be easily measured and could serve as biomarkers for cognitive function.
A previous study involving older Puerto Rican individuals showed that the levels of 13 blood metabolites were associated with global cognitive function, which is a composite measure of multiple cognitive abilities.
Metabolite levels are influenced by the interplay between genetics, health status, and environmental factors, including diet, other lifestyle factors, and socioeconomic factors, which may differ among and even within ethnic/racial groups.
The meta-analysis showed that six blood metabolites were associated with lower cognitive function across all ethnic/racial groups. Four out of the six metabolites associated with overall cognitive function were sugars, including glucose, ribitol, mannose, and mannitol/sorbitol.
Out of the six metabolites, the analysis revealed a potential causal effect of only ribitol on cognitive function.
The researchers also assessed the association between dietary habits, including adherence to a Mediterranean diet and intake of food groups (i.e. intake of legumes, fruits, vegetables, meat, fish, etc.), and blood metabolite levels.
They found that adhering to a Mediterranean diet or its component food groups was correlated with several blood metabolites assessed in the study.
Notably, the strongest association was observed between beta-cryptoxanthin and fruit intake participants.
Beta-cryptoxanthin is a carotenoid with antioxidant properties found in fruits and vegetables, and beta-cryptoxanthin levels are associated with a lower risk of insulin resistance and liver dysfunction.
“[T]his study is a step in the right direction in relation to examining the role of diet and the body’s metabolism for brain health. It provides suggestive evidence that adherence to a good diet such as the Mediterranean style diet may be beneficial for brain health over a wide age range.”
Indigo Rose Tomatoes Contain An Antioxidant That Fights Diabetes, Cancer and Neurodegenerative Diseases
Oregon State University, September 15, 2022
Not only do dark tomatoes turn heads, but they are also healthier than normal red varieties, according to plant scientists. Indigo Rose Tomatoes were cultivated by breeding red and purple tomato plants, and are being heralded as a new superfood with potent antioxidants.
Scientists bred purple tomatoes containing anthocyanin, an antioxidant said to help fight several diseases, with normal red varieties.
‘There are some dark coloured tomatoes but Indigo Rose is the only real black tomato and is the darkest that has ever been bred. “It’s not genetically modified or GMO-based as many assume,” said Botanist Marjorie Varga. “People often get confused between GMO and hybridization which farmers have been using to cultivate new plant varieties for thousands of years.”
“It is the first improved tomato variety in the world that has anthocyanins in its fruit,” he said.
Myers’ team found some tomatoes with purple pigmentation and tests revealed that anthocyanins were providing the colour, the same as blueberries. They crossed the purple tomatoes with some wild tomatoes and eventually came up with a black strain.
Foot massage effective in improving sleep quality and anxiety in postmenopausal womenÇankiri Karatekin University (Turkey), September 21, 2022
The therapeutic benefits of massage have long been recognized. A new study suggests that foot massage, in particular, can help minimize a number of common menopause symptoms, including sleep disruption, effectively extending sleep duration by an average of an hour per day. Study results are published online today in Menopause.
During the menopause transition, estrogen deficiency can lead to a number of physical and mental health problems, including insomnia, hot flashes, vaginal dryness, headaches and anxiety. Although hot flashes and negative moods commonly seen in in the menopause transition often improve, conditions such as sleep complaints and vaginal dryness tend to persist or worsen over time.
Previous studies have suggested that foot reflexology is an effective intervention in reducing stress and fatigue in premenopausal women. However, no previous studies were found that evaluated the effects of foot massage on anxiety, fatigue and sleep at the same time in postmenopausal women.
In this new, small-scale study, researchers specifically sought to evaluate the effects of foot massage on anxiety, fatigue and sleep in postmenopausal women. Study results determined that foot massage applied during menopause increases the average daily sleep duration—as much as an hour per day—and reduces women’s fatigue and anxiety levels.
“Sleep disturbances, fatigue and anxiety symptoms are common during menopause. This small study in Turkish women shows how a simple, inexpensive intervention such as foot massage can improve these bothersome symptoms in postmenopausal women.
Lack of sleep negatively impacts immune stem cells, increasing risk of inflammatory disorders and heart diseaseIcahn School of Medicine at Mount Sinai, September 21, 2022
Chronic insufficient sleep can negatively affect immune cells, which may lead to inflammatory disorders and cardiovascular disease, according to a new study from the Icahn School of Medicine at Mount Sinai. More specifically, consistently losing an hour and a half of sleep a night potentially increases the risk.
The research, published in the Journal of Experimental Medicine, is the first to show that sleep alters the structure of DNA inside the immune stem cells that produce white blood cells—also known as immune cells—and this can have a long-lasting impact on inflammation and contribute to inflammatory diseases. Immune cells fight infection, but if the number of these cells gets too high, they overreact and cause inflammation. The study is also the first to show that catching up on sleep doesn’t reverse the effects of sleep disruption.
“This study begins to identify the biological mechanisms that link sleep and immunological health over the long-term. It shows that in humans and mice, disrupted sleep has a profound influence on the programming of immune cells and rate of their production, causing them to lose their protective effects and actually make infections worse—and these changes are long-lasting. This is important because it is yet another key observation that sleep reduces inflammation and, conversely, that sleep interruption increases inflammation,” says lead author Filip Swirski, Ph.D., Director of the Cardiovascular Research Institute at Icahn Mount Sinai.
“This work emphasizes the importance of adults consistently sleeping seven to eight hours a day to help prevent inflammation and disease, especially for those with underlying medical conditions.”
A team of investigators analyzed 14 healthy adults who regularly sleep eight hours a night. First, researchers monitored them sleeping at least eight hours a night for six weeks. They drew their blood and analyzed their immune cells. Then, the same group of adults reduced their sleep time by 90 minutes every night for six weeks, and had their blood and immune cells reanalyzed.
At the end of the study researchers compared the blood and cell samples from the full night’s sleep and restricted sleep periods. All participants had significant changes in their immune cells (also known as hematopoietic cells) due to a lack of sleep—there were more of them, and the DNA structure was altered. After six weeks of sleep restriction, they had an increased number of immune cells.
Results in humans showed that fragmented sleep had significant changes to their immune stem cells, producing an increased number of immune cells, and also showed evidence of rewiring and reprogramming. A notable finding from the mouse group was that even after sleep recovery, the immune stem cells retained this rewiring structure, and they continued to produce additional white blood cells, making the mice susceptible to inflammation and disease.
“Our findings suggest that sleep recovery is not able to fully reverse the effects of poor-quality sleep. We can detect a molecular imprint of insufficient sleep in immune stem cells, even after weeks of recovery sleep. This molecular imprint can cause the cells to respond in inappropriate ways leading to inflammation and disease,” says co-lead investigator Cameron McAlpine, Ph.D., Assistant Professor of Medicine (Cardiology) at Icahn Mount Sinai.