The Gary Null Show

The Gary Null Show - 09.20.22

Videos:
The Truth About Ivermectin: A new short documentary by Filmmaker Mikki Willis – 13:42
Neil Oliver: This supposed utopia we’re having rammed down our throats isn’t working – 9:58
New Rule: Cancel Culture is Over Party | Real Time with Bill Maher (HBO) – 6:45
 
Antioxidants protect against cartilage damageSkeletal Biology and Engineering Research Center (Belgium), September 12 20228.
An article appearing in Science Translational Medicine adds evidence to the role of antioxidants in protecting the body’s cartilage from the damage that contributes to osteoarthritis.
Acting on the finding that the protein ANP32A, which is involved in a number of processes in the body, was downregulated in osteoarthritic cartilage in mice and humans, Frederique Cornelis of the Skeletal Biology and Engineering Research Center in Belgium and colleagues discovered that ANP32A protects against oxidative damage in the joints, thereby helping to prevent the development of osteoarthritis and its progression. It was determined that ANP32A increases levels of the enzyme ATM, a regulator of the cellular oxidative defense, in response to oxidative stress in joint cartilage.
The discovery suggests that antioxidant therapies could help protect against further damage in patients with osteoarthritis, as well as providing a benefit in other disorders. Administration of the antioxidant N-acetylcysteine (NAC) to the drinking water of mice that were deficient in ANP32A was shown to decrease cartilage damage and arthritis symptoms. It was additionally revealed that ANP32A deficiency was associated with osteopenia and a neurologic disease known as cerebellar ataxia in mice and that NAC helped with these conditions.
“Aging, a key risk factor for the development of osteoarthritis, is associated with elevated oxidative damage of DNA, proteins, and lipids, and accumulating evidence indicates that oxidative stress is a major physiological inducer of aging,” the authors write. “We observed reduced expression of ANP32A in aged mouse cartilage and in human cartilage from patients with osteoarthritis, and we showed that Anp32a-deficient mice develop spontaneous osteoarthritis upon aging. Thus, ANP32A can be considered as a key coordinator of oxidative stress and aging in joints.”
“Our findings indicate that modulating ANP32A signaling could help manage oxidative stress in cartilage, brain, and bone with therapeutic implications for osteoarthritis, neurological disease, and osteoporosis,” they conclude.
Consuming Soy Peptide May Reduce Colon Cancer Metastasis
University of Illinois, September 18, 2022
After a recent University of Illinois study showed that injection of the soy peptide lunasin dramatically reduced colon cancer metastasis in mice, the researchers were eager to see how making lunasin part of the animals’ daily diet would affect the spread of the disease.
“In this new study, we find that giving lunasin orally at 20 mg/kg of body weight reduced the number of metastatic tumors by 94 percent — we went from 18 tumors to only one. And that was done using lunasin alone; no other type of therapy was used,” said Elvira de Mejia, a U of I professor of food chemistry and food toxicology.
“We learned in that study that lunasin can penetrate the cancer cell, cause cell death, and interact with at least one type of receptor in a cell that is ready to metastasize,” said Vermont Dia, a postdoctoral associate in the de Mejia laboratory.
Using mice that had been injected with human colon cancer cells, the scientists began by feeding the animals 8 mg/kg of lunasin daily, which reduced the number of new tumors in the liver by 55 percent. They increased the dose five times, at last achieving a 94 percent reduction in tumors at 20 mg/kg of lunasin.
“We were very impressed by the reduction, but the results were short of statistical significance from the control group. More animals are needed to strengthen the power of the analysis. It’s a small study but very promising,” de Mejia said.
The scientists said that consuming the equivalent of 20 to 30 mg/kg of lunasin in soy foods would be daunting in terms of number of servings per day. “But it would certainly be possible if food companies began to offer lunasin-enriched soy milk or yogurt,” she said, noting that lunasin-enriched flour is already on the market.
Globally, diets are not much healthier today than they were thirty years agoTufts University, September 19, 2022
On a scale from 0 to 100 of how well people stick to recommended diets, with 0 being a poor diet (think heavy consumption of sugar and processed meats), and 100 representing the recommended balance of fruits, vegetables, legumes/nuts and whole grains, most countries would earn a score around 40.3. Globally, this represents a small, but meaningful, 1.5-point gain between 1990 and 2018, researchers from the Friedman School of Nutrition Science and Policy at Tufts University report today in the journal Nature Food.
The study, one of the most comprehensive estimates yet of global dietary quality—and the first to include findings among children as well as adults—highlights the challenges worldwide to encourage healthy eating. Although global gains were modest, there was notable variation by country, with nutritious options becoming more popular in the United States, Vietnam, China, and Iran, and less so in Tanzania, Nigeria, and Japan.
“Intake of legumes/nuts and non-starchy vegetables increased over time, but overall improvements in dietary quality were offset by increased intake of unhealthy components such as red/processed meat, sugar-sweetened beverages, and sodium,” says lead author Victoria Miller, a visiting scientist from McMaster University in Canada who started this study as a postdoctoral scholar with Dariush Mozaffarian, Dean for Policy and Jean Mayer Professor of Nutrition at the Friedman School, and senior author on the paper.
Miller and colleagues addressed this gap by measuring global, regional, and national eating patterns among adults and children across 185 countries based on data from over 1,100 surveys from the Global Dietary Database, a large, collaborative compilation of data on food and nutrient consumption levels worldwide. The researchers’ primary outcome was the 0 to 100 scale known as the Alternative Healthy Eating Index, a validated measure of diet quality.
Regionally, averages ranged from as low as 30.3 in Latin America and the Caribbean to as high as 45.7 in South Asia. The average score of all 185 countries included in the study was 40.3. Only 10 countries, representing less than 1 percent of the world’s population, had scores over 50. The world’s highest scoring countries were Vietnam, Iran, Indonesia and India, and the lowest scoring were Brazil, Mexico, the United States and Egypt.
Globally, among adults, women were more likely to eat recommended diets than men, and older adults more so than younger adults.
Yogic breathing shows promise in reducing symptoms of post-traumatic stress disorder
University of Wisconsin-Madison September 11, 2022
One of the greatest casualties of war is its lasting effect on the minds of soldiers. This presents a daunting public health problem: More than 20 percent of veterans returning from the wars in Iraq and Afghanistan have post-traumatic stress disorder, according to a report by RAND Corp.
A new study from the Center for Investigating Healthy Minds at the Waisman Center of the University of Wisconsin-Madison offers hope for those suffering from the disorder. Researchers there have shown that a breathing-based meditation practice called Sudarshan Kriya Yoga can be an effective treatment for PTSD.
Standard treatment interventions for PTSD offer mixed results. Some individuals are prescribed antidepressants and do well while others do not; others are treated with psychotherapy and still experience residual affects of the disorder.
Sudarshan Kriya Yoga is a practice of controlled breathing that directly affects the autonomic nervous system. While the practice has proven effective in balancing the autonomic nervous system and reducing symptoms of PTSD in tsunami survivors, it has not been well studied until now.
The CIHM team was interested in Sudarshan Yoga because of its focus on manipulating the breath, and how that in turn may have consequences for the autonomic nervous system and specifically, hyperarousal. Theirs is the first randomized, controlled, longitudinal study to show that the practice of controlled breathing can benefit people with PTSD.
The CIHM study included 21 soldiers: an active group of 11 and a control group of 10. Those who received the one-week training in yogic breathing showed lower anxiety, reduced respiration rates and fewer PTSD symptoms.
Cognition May Decline With Old Age, But Well-Being Actually ImprovesUniversity of California, San Diego School of Medicine, September 19, 2022
Children and adolescents usually want to grow up as soon as possible, but most older adults will say they want nothing more than to turn back the clock. Research out of the University of California, San Diego School of Medicine gives both the old and the young reason to envy each other. Scientists say that while older adults usually see a decline in thinking skills, well-being typically increases as we grow older.
More specifically, scientists report that healthy older adults display greater mental well-being than younger adults, but also score lower on cognitive performances. The UCSD team is hopeful that the underlying neural mechanisms identified during this project contributing may inspire new interventions to promote healthy brain function in the future.
Researchers sampled a total of 62 healthy younger adults in their 20s, and 54 healthy older adults over 60. Each subject’s mental health was measured via a survey asking about symptoms including anxiety, depression, loneliness, and overall mental wellbeing. Participants also took part in a series of cognitively demanding tasks, all while their brain activity was measured using electroencephalography (EEG).
Results show that young adults experience far more anxiety, depression, and loneliness than older adults. On the other hand, older individuals show higher levels of well-being. Regarding cognition, older adults, unsurprisingly, were much weaker. The EEG recordings provided further insight, detailing greater activity in the anterior portions of the brain’s default mode network among older adults. This brain area is active when we ruminate, daydream, etc., and is usually suppressed during goal-oriented tasks.Notably, several other brain regions appeared to improve cognition. Strong cognitive scores among young adults were associated with more activity in the dorsolateral prefrontal cortex, which is part of the brain’s executive control system. For older adults, though, those with strong cognitive scores actually displayed greater activity in their inferior frontal cortex, a brain region known to help guide attention and avoid distractions.The dorsolateral prefrontal cortex is known to break down as the body ages. Consequently, researchers theorize that the increased inferior frontal cortex activity among cognitively strong older individuals may be an avenue for older minds to compensate during mentally tougher tasks.
Drinking plenty of tea may reduce the risk of developing type 2 diabetes, finds study in over a million adultsWuhan University of Science and Technology (China), September 17, 2022
A systematic review and meta-analysis of 19 cohort studies involving more than 1 million adults from eight countries finds that moderate consumption of black, green or Oolong tea is linked to a lower risk of developing type 2 diabetes.
The findings, being presented at this year’s European Association for the Study of Diabetes (EASD) Annual Meeting in Stockholm, Sweden suggest that drinking at least four cups of tea a day is associated with a 17% lower risk of T2D over an average period of 10 years.
While it’s long been known that regularly drinking tea may be beneficial for health because of the various antioxidant, anti-inflammatory and anticarcinogenic compounds tea contains, less clear has been the relationship between tea drinking and the risk of T2D. So far, published cohort studies and meta-analyses have reported inconsistent findings.
Overall, the meta-analysis found a linear association between tea drinking and T2D risk, with each cup of tea consumed per day reducing the risk of developing T2D by around 1%.
When compared with adults who didn’t drink tea, those who drank 1-3 cups daily lowered their risk of T2D by 4%, while those who consumed at least 4 cups every day reduced their risk by 17%.
The associations were observed regardless of the type of tea participants drank, whether they were male or female, or where they lived, suggesting that it may be the amount of tea consumed, rather than any other factor, that plays a major role.
“While more research needs to be done to determine the exact dosage and mechanisms behind these observations, our findings suggest that drinking tea is beneficial in reducing the risk of type 2 diabetes, but only at high doses (at least 4 cups a day)”, says Li.
She adds, “It is possible that particular components in tea, such as polyphenols, may reduce blood glucose levels, but a sufficient amount of these bioactive compounds may be needed to be effective. It may also explain why we did not find an association between tea drinking and type 2 diabetes in our cohort study, because we did not look at higher tea consumption.”

The Gary Null Show - 09.19.22

Videos :
New Rule: Let the Population Collapse | Real Time with Bill Maher (HBO) – 8:29
The De-Population Bomb – hoover institution (0:43 – 8:15)
THE GREAT AWAKENING: PLANDEMIC 3 PRELAUNCH PARTY – (21:00 – 30:20)
Gary Null Speaking Out at the NYS Assembly Hearing  (25:00)
 
Meta-analysis finds less fatigue with CoQ10 supplementationNational Yang Ming Chiao Tung University (Taiwan), September 16 2022.
The results of a systematic review and meta-analysis of clinical trials, published in Frontiers in Pharmacology, support an anti-fatigue effect among individuals who supplemented with coenzyme Q10.
“Coenzyme Q10 (CoQ10) is a popular nutritional supplement and a lipid-soluble antioxidant that is endogenously produced by the human body,” authors I-Chen Tsai of National Yang Ming Chiao Tung University and associates observed. “CoQ10 supplementation has been successfully applied for reducing fatigue in patients with various conditions, including chronic fatigue and fibromyalgia, as well as in healthy subjects.”
For their analysis, Tsai colleagues identified 13 randomized, controlled trials that compared fatigue scores of participants who received CoQ10 or a placebo. The trials included a total of 1,126 participants.
Analysis of the 13 trials showed a consistent significant effect for CoQ10 in reducing fatigue. When trials that included healthy participants were analyzed separately from trials that included patients with fatigue-associated diseases, both supplemented populations showed decreases in fatigue, however the effects were significant among the unhealthy participants, who may have more severe CoQ10 depletion. Higher CoQ10 doses and longer duration of supplementation were correlated with increased fatigue reduction.
The anti-fatigue effect of CoQ10 is unsurprising, given its role in energy production. Chronic fatigue syndrome patients have lower plasma levels of CoQ10 in comparison with healthy subjects. While the body makes some CoQ10, the authors remarked that studies have provided evidence that supplementing with CoQ10 does not affect the body’s synthesis of the coenzyme.
Researchers identify a potential new approach with a dietary supplement to treat HER2 positive breast cancerMayo Clinic, September 9, 2022
Researchers at Mayo Clinic have identified an important new pathway by which HER2 positive breast cancers grow and have discovered that a dietary supplement called cyclocreatine may block the growth of HER2 positive breast cancer. Their findings were published in Cell Metabolism.
“The HER2 receptor tyrosine kinase, which functions as an ‘on’ or ‘off’ switch in cellular functions, is a key driver of breast cancer, and is overexpressed in about a quarter of all breast cancers,” says Taro Hitosugi, Ph.D., a pharmacologist at Mayo Clinic and corresponding author of the paper.
Dr. Hitosugi and his colleagues decided to explore ways to resolve an unmet clinical need. Their strategy was to develop a treatment to target tumor mitochondrial energy metabolism, which is the process cancer cells use to manipulate energy during cell metabolism in order to grow.
Dr. Hitosugi and his colleagues discovered that cyclocreatine, a dietary supplement used in sports drinks, effectively targets mitochondrial creatine kinase 1 enzyme and reduces cancer growth without toxicity. This finding was confirmed in mice models where a patient-derived, trastuzumab-resistant HER2 positive tumors were administered to the mice.
“Mitochondrial creatine kinase 1 may be a new drug target for the treatment of HER2 positive breast cancer,” says Matthew Goetz, M.D., director of the Mayo Clinic Breast Cancer research program. “Future clinical trials will be necessary to determine the effectiveness of this drug for HER2 positive breast cancer resistant to standard therapies.”
Excessive smartphone screen time linked to earlier puberty onsetGazi University (Turkey), September 16, 2022
Exposure to blue light, via regular use of tablets and smartphones, may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented at the Annual European Society for Paediatric Endocrinology Meeting.
Longer duration of blue light exposure was associated with earlier puberty onset in the female rats, which also showed reduced levels of melatonin, increased levels of some reproductive hormones and physical changes in their ovaries. Use of blue light-emitting mobile devices has previously been linked to disrupted sleeping patterns in children but these findings suggest there could be additional risks for childhood development and future fertility.
The escalating use of blue light-emitting devices, such as tablets and smartphones, has previously been implicated in reducing sleep quality in both children and adults. This is thought to be through disruption of our body clock as blue light inhibits the evening rise in levels of the hormone, melatonin, which prepares our bodies for rest and sleep. Melatonin levels are overall higher during pre-puberty than in puberty, which is believed to play a role in delaying the start of puberty. Puberty is a complex process that involves co-ordination of several body systems and hormones.
In recent years, several studies have reported increases in early puberty onset for girls, particularly during the COVID-19 pandemic. The link between blue light exposure and reduced melatonin levels suggests that increased screen time, such as during the pandemic restrictions, may be playing a role in this reported increase. However, it is very difficult to assess this in children.
In this study, Dr. Aylin Kilinç Uğurlu and colleagues in Ankara, Turkey, used a rat model to investigate the effects of blue light exposure on reproductive hormone levels and the time of puberty onset. Female rats were divided into three groups of six and exposed to either a normal light cycle, 6 hours or 12 hours of blue light. The first signs of puberty occurred significantly earlier in both groups exposed to blue light, and the longer the duration of exposure, the earlier the onset of puberty. Rats exposed to blue light also had reduced melatonin levels and elevated levels of specific reproductive hormones (estradiol and luteinizing hormone), as well as physical changes in their ovarian tissue, all consistent with puberty onset. At the 12-hour exposure, rats also showed some signs of cell damage and inflammation in their ovaries.
Dr. Aylin Kilinç Uğurlu comments, “We have found that blue light exposure, sufficient to alter melatonin levels, is also able to alter reproductive hormone levels and cause earlier puberty onset in our rat model. In addition, the longer the exposure, the earlier the onset.”
Fitness trackers reveal links among exercise, memory, and mental healthDartmouth College, September 15, 2022
Exercise can improve your cognitive and mental health—but not all forms and intensities of exercise affect the brain equally. The effects of exercise are much more nuanced, as specific intensities of exercise over a long period of time are associated with different aspects of memory and mental health, according to a new Dartmouth study. The findings are published in Scientific Reports and provide insight into how exercise could be optimized.
“Mental health and memory are central to nearly everything we do in our everyday lives,” says lead author Jeremy Manning, an assistant professor of psychological and brain sciences at Dartmouth. “Our study is trying to build a foundation for understanding how different intensities of physical exercise affect different aspects of mental and cognitive health.”
The researchers asked 113 Fitbit users to perform a series of memory tests, answer some questions about their mental health, and share their fitness data from the previous year. They expected that more active individuals would have better memory performance and mental health, but the results were more nuanced. People who tended to exercise at low intensities performed better at some memory tasks while those who exercised at a high intensities did better on other memory tasks. Participants who were more intensely active also reported higher stress levels, whereas people who regularly exercised at lower intensities showed lower rates of anxiety and depression.
Participants who had been more active over the prior year tended to show better memory performance overall, but the specific areas of improvement depended on which types of activity people did. The researchers found that participants who often exercised at moderate intensities tended to perform better on the episodic memory tasks while participants who often exercised at high intensities did better on the spatial memory tasks. Sedentary participants who seldom exercised tended to perform worse on the spatial memory tasks.
The researchers also identified connections between participants’ mental health and their memory performance. Participants with self-reported anxiety or depression tended to perform better on the spatial and associative memory tasks, while those with self-reported bipolar disorder tended to perform better on the episodic memorytasks. Participants who reported higher levels of stress tended to perform worse on the associative memory tasks.
Positive psychological well-being can improve overall heart healthNorthwestern University, September 10, 2022Maintaining positive thoughts and feelings through intervention programs can help patients achieve better overall outcomes when it comes to their cardiovascular health, according to a review paper published in the Journal of the American College of Cardiology.
“We addressed how social environment, psychological well-being and the effectiveness of intervention strategies can help strengthen a patient’s outlook,” said Darwin R. Labarthe, MD, MPH, Ph.D., professor of Preventive Medicine at Northwestern University Feinberg School of Medicine and the review’s lead author. “We focused on whether psychological well-being can be consistently related with a reduced risk of heart disease.”
In this review, the authors looked at a growing body of research to examine whether psychological well-being might lead to reduced risk of heart disease. Prospective studies have shown a positive relationship between optimism (one facet of psychological well-being) and heart disease, including a study showing older women in the highest quartile of optimism had a 38 percent reduced risk of heart disease mortality. Additional studies since 2012 have associated a perceived higher purpose in life with lower odds of having a stroke.
Optimistic patients sustained healthier diets by consuming more fruits and vegetables, and less processed meats and sweets, leading patients to maintain a healthy BMI.
The review authors found that psychological well-being influenced heart health through biological processes, health behaviors and psychosocial resources.
Having a strong network of social support also gives patients confidence about their future health and helps them act readily on medical advice, engage in problem solving and take active preventive measures. A likely link is that favorable social environment, known to influence heart disease risk, has also been shown to predict psychological well-being.
Milk thistle protects against COPD caused by secondhand smokeSichuan University, (China), September 11, 2022
According to the U.S. Centers for Disease Control and Prevention (CDC), 15.7 million people suffer from chronic obstructive pulmonary disease (COPD) – a serious respiratory condition which can cause scarring of the lungs, narrowing of the airway and extreme difficulty breathing. Taking enough milk thistle – on a regular basis – can help protect you from harm.
Exposure to tobacco smoke – whether through actively smoking or simply inhaling the smoke from another’s cigarette – is the primary cause of COPD. Although Western medicine currently offers no cure for COPD, recent studies generate a ray of hope. Groundbreaking new research suggests that milk thistle extracts may not only prevent COPD but, help to treat it.
In a study published in the journal Inflammation, researchers exposed mice to the equivalent of 1.5 packs of cigarettes a day for four weeks, creating drastic increases in peribronchial inflammation, thickening of airway walls and airway obstruction.
The team found that pretreating the mice with silymarin – the active component of milk thistle – an hour before exposure dramatically decreased inflammatory changes, and cut production of pro-inflammatory chemicals such as TNF-alpha and interleukin.
Encouragingly, silymarin also helped safeguard levels of superoxide dismutase, an important disease-fighting antioxidant produced in the body.
A year later, the same team of researchers took another, closer look at the workings of milk thistle. And what they found was encouraging.
In a study of human bronchial cells published in Scientific Report, the team explored the molecular and cellular mechanisms of silymarin – and found once again that the flavonoid attenuated cigarette smoke-induced upregulation of pro-inflammatory chemicals.
And, researchers discovered for the first time that silymarin modulated a certain pathway – known as MAPK – that governs inflammation.
The takeaway? The team concluded that silymarin might be “an ideal agent for treating inflammatory pulmonary diseases.”
In a third study, recently published in Food and Chemical Toxicology, researchers treated mice with silibinin (a constituent of silymarin) one hour before exposure to cigarette smoke.The team found that the silibinin caused the mice to not only experience the sharp reductions in inflammatory changes seen in earlier studies – but discovered that it also suppressed the scarring and fibrosis that are typical of COPD in humans.
This means that silibinin may not only help prevent COPD – but, reverse it!
Intriguingly, the silibinin directly affected the expression of a certain pro-inflammatory protein – transforming growth factor beta-1 – that is activated and spurred on by exposure to smoke, making it appear that this compound is custom-designed to protect against secondhand smoke.
Milk thistle extracts are available in the form of pills, powders, extracts, liposomes and teas. Look for a high-quality preparation that is standardized to contain 70 to 80 percent silymarin.

The Gary Null Show - 09.16.22

VIDEOS :
WES2022 | Yuval Noah Harari and Vanessa Nakate in conversation (3:19)
Why Colleges Are Becoming Cults [Full Series] | Dr. Lyell Asher (15:00 to 43:42
Gary Null Speaking Out at the NYS Assembly Hearing  (25:00)
 
Astragulus found to inhibit breast cancer cell proliferationFujian University of Traditional Medicine (China), September 8, 2022Huang qi (Astragalus) is one of the fundamental herbs in traditional Chinese medicine, with earliest records of its use dating back over 2,000 years ago. Now, a study in BMC Complementary and Alternative Medicine has found that astragulus is also able to prevent the spread of breast cancer cells in the body.
In the study, researchers from the Fujian University of Traditional Chinese Medicine in China looked at how astragulus extract can affect breast cancer cells and the process behind this biological effect. They also looked at the primary isoflavones in the extract, as well as its anti-proliferative activity on three breast cancer lines: MCF-7 (ER+), SK-BR-3 (HER2+) and MDA-MB-231 (triple-negative). They did this by exposing these breast cancer cells to the extract for 48 hours.
In addition, they examined the effect of astragulus extract on phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K)/protein kinase B (Akt)/mammalian target of rapamycin (mTOR) signaling pathways, a primary intracellular signaling pathway that contributes to cell proliferation, growth, migration, metabolism, and apoptosis.
The results of the study showed that the treatment of astragulus exhibited anti-proliferative activity on breast cancer cells. Furthermore, the therapy promoted the death of breast cancer cells. These suggested that it’s ability to inhibit breast cancer cell growth was linked to its ability to inhibit PI3K/Akt/mTOR activity. Moreover, the researchers found that the Huang qi extract contains four types of isoflavones, such as campanulin, ononin, calycosin, and formononetin, which contributed to the inhibitory effect of Huang qi extract on breast cancer cells proliferation.
Vitamin D supplementation could help critically ill patientsUniversity Hospital Würzburg (Germany) September 12 2022.
Findings from a review and meta-analysis reported in Critical Care suggest that providing critically ill patients with vitamin D supplements may improve some clinical outcomes, including survival.
“Upon ICU admission, the majority of patients have significantly reduced 25-hydroxyvitamin D levels, which remain significantly reduced over the entire ICU length of stay,” Johannes Menger and colleagues wrote. “In these patients, significantly reduced vitamin D (25-hydroxyvitamin D) serum levels are frequent and independently associated with higher incidence and severity of sepsis.”
Sixteen randomized, controlled trials that evaluated vitamin D supplementation’s association with mortality were identified.
Vitamin D supplementation was associated with a 22% lower risk of overall mortality in comparison with a placebo or standard care. Among studies that reported 28-day mortality, vitamin D supplementation was associated with a trend toward lower a lower risk. Receiving vitamin D by injection or intravenously had the strongest effect. Patients who received vitamin D spent an average of 3.13 days less in the ICU and 5 fewer days on a ventilator than those who received a placebo.
“The results of this systematic review and meta-analysis suggest that vitamin D supplementation may be associated with reduced overall mortality in critically ill patients,” they concluded.
Natural compound could reduce breast cancer risk in some women
Luteolin may inhibit growth of human breast cancer cells in postmenopausal women taking hormone replacement therapy
University of Missouri-Columbia, September 9, 2022
More than 100 women die from breast cancer every day in the United States. The odds increase in postmenopausal women who have taken a combined estrogen and progestin hormone replacement therapy; these women also have an increased risk of developing progestin-accelerated breast tumors. Now, University of Missouri researchers have found that luteolin, a natural compound found in herbs such as thyme and parsley as well as vegetables such as celery and broccoli, could reduce the cancer risk for women who have taken hormone replacement therapy.
“Most older women normally have benign lesions in breast tissue,” Hyder said. “These lesions typically don’t form tumors until they receive the ‘trigger’– in this case, progestin–that attracts blood vessels to cells essentially feeding the lesions causing them to expand.” His newest study shows that when the supplement luteolin is administered to human breast cancer cells in the lab, benefits can be observed including the reduction of those vessels “feeding” the cancer cells causing cancer cell death.
Hyder’s lab has found that as human breast cancer cells develop, they tend to take on stem cell-like properties, which can make them harder to kill. Here, luteolin was used to monitor stem cell-like characteristics of breast cancer cells and his team saw a vast reduction in this phenomenon, further proving that the natural compound exerts its anti-tumor effects in a variety of ways.
“We feel that luteolin can be effective when injected directly into the bloodstream, so IV supplements may still be a possibility,” Hyder said. “But, until the supplement is tested for safety and commercialized, which we hope will happen after further testing and clinical trials, women should continue consuming a healthy diet with fresh fruits and vegetables.”
CBD shows health benefits in estrogen-deficient mice that model postmenopauseRutgers University, September 14, 2022
A Rutgers study points to cannabidiol (CBD), a major component of hemp and medical marijuana used to treat conditions such as chronic pain, inflammation, migraines, epilepsy, autoimmune diseases, depression, and anxiety, as a possible treatment for postmenopausal women whose ovaries no longer make estrogen.
In a study published in Frontiers in Pharmacology, scientists reported that when estrogen-deficient mice were fed CBD, a non-intoxicating compound extracted from hemp, they showed marked improvement in several areas. Their bloodstreams more readily disposed of glucose, and they burned more energy. In addition, their bone density improved, they had less inflammation in gut and bone tissues and they possessed higher levels of beneficial gut bacteria.
“This preclinical study is the first to suggest the therapeutic potential of CBD for alleviating symptoms of estrogen deficiency,” said Diana Roopchand, an assistant professor in the Department of Food Science of the Rutgers School of Environmental and Biological Sciences (SEBS) and senior author on the study. “There is much anecdotal evidence of CBD’s health benefits for menopausal and postmenopausal women, but our study is the first to investigate some of the claims in an established preclinical model of postmenopause.”
Over 18 weeks, researchers fed the estrogen-deficient mice a steady diet of either tiny, CBD-laced peanut butter balls or peanut butter balls without CBD. The untreated estrogen-deficient mice developed symptoms that resembled those of postmenopausal human females, such as metabolic dysfunction, evidence of inflammation, lower bone density, and lower levels of beneficial gut bacteria. However, in mice that ingested CBD, these conditions were significantly improved.
Mediterranean diet and depression among older individualsHarokopio University (Greece), September 9, 2022According to news originating from Athens, Greece,research stated, “In Europe, depression is one of the most frequent mental disorders across all age groups, but particularly in people aged 65 years and over, and higher depressive symptoms have been reported among individuals with chronic diseases (e.g., diabetes and heart disease).”
Research from Harokopio University stated, “To evaluate the role of adherence to the Mediterranean diet (MedDiet) in depression in a sample of older people living in the Mediterranean basin. Standard procedures were used to determine socio-demographic, lifestyle, and clinical characteristics of the participants, as well as their dietary habits, and depressive symptoms were evaluated using the Geriatric Depression Scale (GDS). Participants classified as having mild or severe depression were less educated and physically active, and more diabetic, and they reported less adherence to the MedDiet. Adherence to the MedDiet was associated with the absence of depression [(OR, 95% CI): 0.65, 0.50 – 0.85]. In addition, daily tea drinking was also related to the absence of depression [(OR, 95% CI): 0.51, 0.40 – 0.65].”
According to the news editors, the research concluded: “Greater adherence to the MedDiet and daily tea drinking seem to have a beneficial effect on depressive symptoms in older adults.”
High cholesterol leads to long-term liver scarring and immune cell dysfunction in lab studyUniversity of Southern California, September 15, 2022
There’s a long-established link between a high-fat, high-sugar diet and fatty liver disease, which can lead to life-threatening conditions such as cirrhosis and liver cancer. Now, new research from the Keck School of Medicine of USC adds some detail and dimension to this picture.
The lab study, published in Frontiers in Immunology, is the first-ever to focus on how different amounts of cholesterol as part of a diet high in fat and sugar affect fatty liver disease progression. Modeling the disease in mice, the investigators demonstrated that high cholesterol intake can make fatty liver disease worse—driving inflammation and scarring—and that, importantly, scar tissuecan persist even after switching to a diet low in cholesterol. The findings also indicated that a high-cholesterol diet can create long-lasting dysfunction in a specific population of immune cells previously shown to play a role in fatty liver disease.
“We saw that you may have a high-fat and high-sugar diet, but when you add high cholesterol to that, it will accelerate the process that causes inflammation in your liver,” said corresponding author Ana Maretti-Mira, Ph.D., an assistant research professor of medicine at USC. “People focus on high cholesterol as a risk for heart disease, but we showed that your liver may also be affected, causing inflammation, scarring and, potentially, cirrhosis.”
High cholesterol makes fatty liver disease worse
The researchers fed mice a high-fat, high-sugar diet shown to cause a form of advanced fatty liver disease similar to human illness.
The mice were split into three groups that received different amounts of cholesterol in their food for 20 weeks—midlife for the animals. The low-cholesterol group received one-quarter the cholesterol compared to medium; the high-cholesterol group received 25 times more than the low-cholesterol group.
After 20 weeks, the livers of mice from all three groups showed accumulation of fat, a benign feature of fatty liver disease, but the high-cholesterol group had more advanced disease, with increased inflammation and scar tissue.
For the following 10 weeks, mice from all three groups received low cholesterol as part of a diet that remained high in fat and sugar. At the end of that time, that change in diet had reversed inflammation in the original high-cholesterol mice, but had not reduced scar tissue. This finding shows that damage caused by high cholesterol can be hard to undo.
The high-fat, high-sugar diet given to mice in the study has unfortunate similarities to the typical Western diet in humans.
“Our daily diet has lots of carbohydrates, such as sugary drinks, bread, rice and pasta,” Maretti-Mira said. “Then there’s high fat, since everybody likes deep fried foods. At the same time, we don’t have the same active life we used to, so we end up eating much more than our body needs.”

The Gary Null Show - 09.15.22

Videos :
 
ELDERLY SUICIDE – This is Agenda 21 – MUST SEE!
2022 Fauci, meet 2004 Fauci. FACT CHECK: it did not go well for 2022 Fauci.  (1:23)
Sam Bailey & Jessic Rose Part 1 (22:33)
Gary Null Speaking Out at the NYS Assembly Hearing  (25:00)
 
Higher omega-3 levels linked to better sleep
University of British Columbia, September 14 2022. 
Having higher blood concentrations of the omega-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA) was found to be associated with a reduction in excessive sleep in an analysis reported in 2022 in the American Journal of Clinical Nutrition.
Sleep duration of over 9 hours per night has been correlated with an increased risk of cardiovascular disease and premature mortality from all causes.
The analysis included 21,653 participants in 12 studies for whom information was available concerning sleep duration and/or difficulty falling asleep and blood levels of the omega-3 fatty acids EPA, DHA, ALA and, when available, DPA, and the omega-6 fatty acids AA and LA.
When men and women whose fatty acid levels were among the lowest 20% of participants were compared to those whose levels were among the top 20%, individuals whose DHA intake was highest had a 22% lower risk of excessive sleep. Being among those who had the highest intake of EPA plus DHA and DPA was associated with a 24% lower risk. The authors noted that DHA’s role in regulating melatonin production helps regulate sleep. 
Twice-daily nasal irrigation reduces COVID-related illness, death
Medical College of Georgia at Augusta University, September 13, 2022
Starting twice daily flushing of the mucus-lined nasal cavity with a mild saline solution soon after testing positive for COVID-19 can significantly reduce hospitalization and death, investigators report.
They say the technique that can be used at home by mixing a half teaspoon each of salt and baking soda in a cup of boiled or distilled water then putting it into a sinus rinse bottle is a safe, effective and inexpensive way to reduce the risk of severe illness and death from coronavirus infection that could have a vital public health impact. 
“By giving extra hydration to your sinuses, it makes them function better.
“We found an 8.5-fold reduction in hospitalizations and no fatalities compared to our controls,” says senior author Dr. Richard Schwartz, chair of the MCG Department of Emergency Medicine. “Both of those are pretty significant endpoints.”
The study appears to be the largest, prospective clinical trial of its kind and the older, high-risk population they studied—many of whom had preexisting conditions like obesity and hypertension—may benefit most from the easy, inexpensive practice, the investigators say.
They found that less than 1.3% of the 79 study subjects age 55 and older who enrolled within 24-hours of testing positive for COVID-19 between Sept. 24 and Dec. 21, 2020, experienced hospitalization. No one died. 
Researchers know that the more virus that was present in your body, the worse the impact. “One of our thoughts was: If we can rinse out some of the virus within 24 hours of them testing positive, then maybe we can lower the severity of that whole trajectory,” she says, including reducing the likelihood the virus could get into the lungs, where it was doing permanent, often lethal damage to many.
Baxter says the nasal irrigation with saline helps decrease the usual robust attachment. Saline appears to inhibit the virus’ ability to essentially make two cuts in itself, called furin cleavage, so it can better fit into an ACE2 receptor once it spots one.
Participants self-administered nasal irrigation using either povidone-iodine, that brown antiseptic that gets painted on your body before surgery, or sodium bicarbonate, or baking soda, which is often used as a cleanser, mixed with water that had the same salt concentration normally found in the body.
Those who completed nasal irrigation twice daily reported quicker resolution of symptoms regardless of which of two common antiseptics they were adding to the saline water.
Eating more spicy foods decreases your risk of early death by 14%
Chinese Academy of Medical Sciences, September 7, 2022
According to an international team of researchers led by the Chinese Academy of Medical Sciences, eating spicy foods may be the key to longevity. They found that eating such foods on a regular basis can help prevent people from dying prematurely by 14 percent. While a variety of spicy foods are excellent, one in particular caught their attention.It was noted that consumption of fresh chili pepper, compared to other spicy foods, was most effective in providing people with a lower risk of dying from cancer, ischemic heart disease and diabetes. It’s explained that fresh chili pepper’s combination of powerful ingredients are responsible for such health-boosting benefits.(1)
“Compared with non-fresh spicy foods such as dried chilli pepper, chilli sauce or chilli oil,” says Lu Qi, associate professor at Harvard School of Public Health, “fresh chilli pepper is richer in bioactive ingredients, including capsaicin, vitamin C, and other nutrients such as vitamin A, K, and B6 and potassium.”(1)
To conduct the study, the experts from the Chinese Academy of Medical Sciences assessed nearly 490,000 participants.
After a follow-up that averaged approximately seven years, 20,224 deaths were noted. Analysis of these people led to the finding that compared to those who ingested spicy foods less than once weekly, people who ate such foods one or two days per week had a 10 percent reduced risk of death. More impressive however, was the discovery that those who enjoyed spicy foods nearly every other day were at a 14 percent lowered risk of death compared to those who ate them less than once a week.
In this large prospective study, we observed an inverse association between consumption of spicy foods and total mortality, after adjusting for potential confounders. Compared with those who ate spicy foods less than once a week, those who consumed spicy foods almost every day had a 14% lower risk of death. Inverse associations were also observed for deaths due to cancer, ischemic heart diseases, and respiratory diseases. The associations were consistent in men and women.
Meditation holds the potential to help treat children suffering from traumas, difficult diagnoses or other stressorsWayne State University, September 13, 2022
Children actively meditating experience lower activity in parts of the brain involved in rumination, mind-wandering and depression, our team found in the first brain-imaging study of young people under 18 years old. Over-activity in this collection of brain regions, known as the default mode network, is thought to be involved in the generation of negative self-directed thoughts – such as “I am such a failure” – that are prominent in mental disorders like depression.
In our study, we compared a simple form of distraction – counting backward from 10 – with two relatively simple forms of meditation: focused attention to the breath and mindful acceptance. Children in an MRI scanner had to use these techniques while watching distress-inducing video clips, such as a child receiving an injection.
We found that meditation techniques were more effective than distraction at quelling activity in that brain network. This reinforces research from our lab and others showing that meditation techniques and martial arts-based meditation programs are effective for reducing pain and stress in children with cancer or other chronic illnesses – and in their siblings – as well as in schoolchildren during the COVID-19 pandemic.
Researchers know a lot about what is happening in the brain and body in adults while they meditate, but comparable data for children has been lacking. Understanding what is happening in children’s brains when they meditate is important because the developing brain is wired differently from the adult brain. 
Pace as important as 10,000 steps for health, finds new research
University of Sydney and University of South Denmark, September 13, 2022
Two studies, published in JAMA Internal Medicine and JAMA Neurology, monitored 78,500 adults with wearable trackers—making these the largest studies to objectively track step count in relation to health outcomes.
The researchers from the University of Sydney, Australia and University of Southern Denmark found lowered risk of dementia, heart disease, cancer and death are associated with achieving 10,000 steps a day. However, a faster stepping pace like a power walk showed benefits above and beyond the number of steps achieved.
“The take-home message here is that for protective health benefits people could not only ideally aim for 10,000 steps a day but also aim to walk faster,” said co-lead author Dr. Matthew Ahmadi, Research Fellow at the University of Sydney’s Charles Perkins Centre and Faculty of Medicine and Health.
Key points:
Every 2,000 steps lowered risk of premature death incrementally by 8 to 11 percent, up to approximately 10,000 steps a day.
Similar associations were seen for cardiovascular disease and cancer incidence.
A higher number of steps per day was associated with a lower risk of all-cause dementia
9,800 steps was the optimal dose linked to lower risk of dementia by 50 percent, however risk was reduced by 25 percent at as low as 3,800 steps a day
Feed a virus, starve a bacterial infection?
Yale University, September 8, 2022
A new study puts some old folk wisdom to “feed a cold and starve a fever” to the test. In mouse models of disease, Yale researchers looked at the effects of providing nutrients during infection and found opposing effects depending on whether the infections were bacterial or viral. 
Mice with bacterial infections that were fed died, while those with viral infections who were fed lived.
“We were surprised at how profound the effects of feeding were, both positive and negative,” says senior author Ruslan Medzhitov, David W. Wallace Professor of Immunobiology and a Howard Hughes Medical Institute investigator at Yale School of Medicine.
In the first series of experiments, the investigators infected mice with the bacterium Listeria monocytogenes, which commonly causes food poisoning. The mice stopped eating, and they eventually recovered. But when the mice were force fed, they died. The researchers then broke the food down by component and found fatal reactions when the mice were given glucose, but not when they were fed proteins or fats.
When the researchers did similar studies in mice with viral infections, they found the opposite effect. Mice infected with the flu virus A/WSN/33 survived when they were force fed glucose, but died when they were denied food or given 2-DG.

The Gary Null Show - 09.14.22

Video:
 
CBS New Report – The Unvaxed Want There Jobs Back  (1:54)
Fired Pediatric ICU Nurse Slamming San Diego County Board of Supervisor (2:04)
The Internet of Bodies | Karen Kingston Shares the Patents That Prove The ENTIRE The Internet of Bodies (4:35)
Douglas Murray and Peter Boghossian – Woke ideology, the university, and grievance (14:41)
 
Onion extracts lower blood pressure for hypertensives: study
University of Bonn (Germany), September 7, 2022
Taking onion skin-derived food supplements of the flavonol quercetin can lower blood pressure for people with hypertension, according to a new study published in the British Journal of Nutrition.
Researchers from the University of Bonn in Germany conducted a double-blind study on 68 overweight or obese volunteers with pre-hypertension or stage 1 hypertension, giving them either a quercetin-rich onion skin extract supplement or a placebo for six weeks.
While the subjects who were not classed as having high blood pressure did not show significant changes, those with high blood pressure saw positive results.
“Supplementation with 162 mg/d quercetin from onion skin extract lowers [ambulatory blood pressure] in patients with hypertension, suggesting a cardioprotective effect of quercetin. The mechanisms responsible for the [blood pressure]-lowering effect remain unclear,” wrote the study’s authors.
Quercetin is an antioxidant commonly found in plants, including onions, kale, apple skins, berries, citrus fruits and tea.
Participants with hypertension saw their systolic blood pressure fall an average of 3.6 mmHg, which the authors suggested “would be clinically meaningful when considered at the population level, particularly in view of the large population of people with pre-hypertension and stage I hypertension”.
The dose of 162 mg per day of quercetin-rich onion skin extract, in the form of three 54 mg capsules, was identified as being approximately 10 to 15 times the normal daily quercetin intake for people in the European Union. The study excluded people who consumed high levels of quercetin in their normal diets.
Older adults with regular activity routines are happier and do better on cognitive tests, study findsUniversity of Pittsburgh, September 12, 2022
Older adults who consistently get up early and remain active throughout the day are happier and perform better on cognitive tests than those with irregular activity patterns, according to a new study led by University of Pittsburgh researchers.
The findings, published online in JAMA Psychiatry, suggest that patterns of activity—not just activity intensity—are important for healthy aging and mental health.
“There’s something about getting going early, staying active all day and following the same routine each day that seems to be protecting older adults,” said lead author Stephen Smagula, Ph.D., assistant professor of psychiatry and epidemiology at Pitt. “What’s exciting about these findings is that activity patterns are under voluntary control, which means that making intentional changes to one’s daily routine could improve health and wellness.”
To learn more about daily activity patterns in U.S.-based older adults and identify links with mental health and cognition, Smagula and his team recruited 1,800 senior citizens aged over 65. Participants wore accelerometers—movement-detecting devices often found in smartphones and exercise trackers—on their wrists for seven days to measure activity, and they completed questionnaires to assess depression symptoms and cognitive function.
The analysis showed that 37.6% of participants rose early in the morning, stayed active throughout the day and had consistent daily routines.
Another group comprising 32.6% of participants similarly had consistent daily patterns but the participants were active for an average of just 13.4 hours each day because they rose later in the morning or settled down earlier in the evening. This group had more depression symptoms and poorer cognition than the early risers.
The remaining 29.8% of participants had disrupted activity patterns in which periods of activity were erratic throughout the day and inconsistent across days. These adults had the highest rates of depression and performed worst on cognitive tests.
Smagula said that the first step to developing a consistent routine and getting better sleep is waking up at the same time each day—no matter how tired you are.
“The other thing is having a realistic plan to keep active through the whole day. This can be really hard—especially if you’re in a slump or recovering from an injury—so it’s important to be reasonable with yourself,” he added. “A plan could include making a list of activities you enjoy and scheduling time to meet a friend or neighbor.”
Weight loss water: Drinking before each meal aids weight reduction
University of Birmingham (UK), September 9, 2022
Drinking 500 ml of water around 30 minutes before main meals could help obese and overweight people to lose more weight, according to new research.
The study, published in Obesity, tested the simple intervention of ‘preloading’ with water over a 12 week period – finding that people who drank 500ml of water at half an hour before eating main meals lost, on average, 1.3kg (2.87lbs) more than those in the control group who did not preload.
“The beauty of these findings is in the simplicity,” commented study lead author Dr Helen Parretti, who is from the University of Birmingham, UK. “Just drinking a pint of water, three times a day, before your main meals may help reduce your weight.”
Indeed, the UK-based team reported that preloading before all three main meals in the day resulted in an average loss of 4.3kg (9.48lbs) over the 12 weeks, whereas those who only preloaded once, or not at all, lost an average of 0.8kg (1.76lbs).
“Losing a few extra pounds over the course of a year can be significant to an individual, and this could be an easy way to help with that weight loss,” Parretti added. “It’s a simple message that has the potential to make a real contribution to public health.”
After twelve weeks, Parretti and her team measured weight loss between the two groups – finding that participants who were instructed to consume 500 ml of water 30 min before main meals lost 1.3 kg more than the comparator group.
According to the findings, 27% of those in the preloading intervention group lost more than 5% of their body weight during the 12 week trial, while only 5% in the comparator group lost the same amount.
Exercise hormone halts Parkinson’s disease symptoms in mouse studyJohns Hopkins University School of Medicine, September 12, 2022
Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson’s disease and halts movement problems in mice.
If confirmed in additional laboratory research and clinical trials, the researchers’ study in mice engineered to have Parkinson’s disease symptoms could pave the way for a Parkinson’s disease therapy based on the hormone irisin.
In the past decade, other laboratories have found that exercise elevates levels of irisin, and there is interest in looking into the connection between irisin and Alzheimer’s disease as well as Parkinson’s disease.
In the laboratory model, the researchers found that irisin prevented the accumulation of alpha synuclein clumps and its associated brain cell death.
Additional studies of brain cells among the mice given irisin showed that the exercise hormone lowered levels of Parkinson’s disease-related alpha synuclein between 50% and 80%. The research team demonstrated that irisin also speeds up the transport and degradation of alpha synuclein via fluid-filled sacs called lysosomes in brain cells.
Common antidepressant may change brain
Wake Forest Baptist Medical Center, September 4, 2022
A commonly prescribed antidepressant may alter brain structures in depressed and non-depressed individuals in very different ways, according to new research at Wake Forest Baptist MedicalCenter.
The study – conducted in nonhuman primates with brain structures and functions similar to those of humans – found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects.
In the study, 41 middle-aged female monkeys were fed a diet formulated to replicate that consumed by many Americans for 18 months, during which time depressive behavior in the animals was recorded. Female monkeys were chosen for this study because depression is nearly twice as common in women as men and the use of antidepressants is most common in women ages 40 to 59.
After the 18-month pre-study phase, the monkeys were divided into two groups balanced for body weight, body mass index and depressive behavior. For the next 18 months, 21 monkeys received sertraline in daily doses comparable to those taken by humans while a group of 20 received a placebo. This treatment regimen is analogous to a human taking an antidepressant for approximately five years.
MRI images taken at the end of the treatment phase revealed that in depressed subjects the drug significantly increased the volume of one region of the brain, the anterior cingulate cortex, while decreasing the volume of this same region and the hippocampus in non-depressed subjects. Both of these areas are highly interconnected with other areas of the brain; are critical in a wide array of functions including memory, learning, spatial navigation, will, motivation and emotion; and are implicated in major depressive disorder.
Daytime eating may benefit mental healthBrigham and Women’s Hospital, September 12, 2022
Beating the blues with food? A new study adds evidence that meal timing may affect mental health, including levels of depression- and anxiety-related mood. Investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham health care system, designed a study that simulated night work and then tested the effects of daytime and nighttime eating versus daytime eating only. The team found that, among participants in the daytime and nighttime eating group, depression-like mood levels increased by 26% and anxiety-like mood levels by 16%. Participants in the daytime-only eating group did not experience this increase, suggesting that meal timing may influence mood vulnerability. Results are published in the Proceedings of the National Academy of Sciences.
“Our findings provide evidence for the timing of food intake as a novel strategy to potentially minimize mood vulnerability in individuals experiencing circadian misalignment, such as people engaged in shift work, experiencing jet lag, or suffering from circadian rhythm disorders,” said co-corresponding author Frank A. J. L. Scheer, Ph.D., Director of the Medical Chronobiology Program in the Brigham’s Division of Sleep and Circadian Disorders.
The team found that meal timing significantly affected the participants’ mood levels. During the simulated night shift (day 4), those in the Daytime and Nighttime Meal Control Group had increased depression-like mood levels and anxiety-like mood levels, compared to baseline (day 1). In contrast, there were no changes in mood in the Daytime Meal Intervention Group during the simulated night shift. Participants with a greater degree of circadian misalignment experienced more depression- and anxiety-like mood.
“Meal timing is emerging as an important aspect of nutrition that may influence physical health,” said Chellappa. “But the causal role of the timing of food intake on mental health remains to be tested. Future studies are required to establish if changes in meal timing can help individuals experiencing depressive and anxiety/anxiety-related disorders.”

The Gary Null Show - 09.13.22

VIDEO:
Interview with Dr. Katarina (“Kat”) Lindley (32:45)
Plandemic – Indoctornation (19:26)
Science For Hire Trailer (4:45)
 
Declaration of An International Medical Crisis and Vaccination as a Cause of Rapid Increases in mortality 
Dr. Katarina Lindley is a board-certified family physician with a direct primary care practice in Texas.  Having grown up in Croatia war-torn Yugoslavia, she traveled and lived in Western Europe before arriving in the US to attend medical school in Florida. In addition to her clinical practice Kat has been active in medical activism to improve our broken healthcare system.  Kat is an active member in several medical and civic organizations including the American Academy of Physicians and Surgeons and the American College of Osteopathic Family Physicians. She is on the Steering Committee of World Council for Health, a global network of over 130 organizations in 40 countries taking a lead in addressing the failures of government health ministries failures in dealing with the Covid-19 pandemic. ahe has testified in various health committees in the USA and internationally, including giving testimony at the FDA against the scientific rationale to vaccinate children with the Covid vaccines and boosters. Kat’s website is KatLindleyDO.com and WorldCouncilForHealth.org

The Gary Null Show - 09.12.22

Video:
WARNING! Is This Man WORSE Than Klaus Schwab? - The Kwak Brothers (7:13)
Gravitas: World teetering on the edge of a global recession (7:18)
PLANDEMIC 2 Indoctornation Documentary - COVID-19

The Gary Null Show - 09.09.22

Videos:
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 Neil Oliver: 'Don’t be fooled into thinking this disaster movie is coming to an end' (11:25)
Glen Ford Ukraine 2014 remarks (7:43)

The Gary Null Show - 09.08.22

Video:
Scientist Carl Sagan testifying to the U.S. Senate in 1985 on the greenhouse effect: (2:00)
WEF: The Most Evil Business in the World – Samuel Leeds (10:49)
Israel caught hiding BOMBSHELL Pfizer
 
Frequent nut consumption associated with less inflammation
Brigham and Women’s Hospital, September 1, 2022
In a study of more than 5,000 people, investigators from Brigham and Women’s Hospital have found that greater intake of nuts was associated with lower levels of biomarkers of inflammation, a finding that may help explain the healthbenefits of nuts. The results of the study appear in the American Journal of Clinical Nutrition.
“Population studies have consistently supported a protective role of nuts against cardiometabolic disorders such as cardiovascular disease and type 2 diabetes, and we know that inflammation is a key process in the development of these diseases,” said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH’s Channing Division of Network Medicine. “Our new work suggests that nuts may exert their beneficial effects in part by reducing systemic inflammation.”
Previously Bao and her colleagues observed an association between increased nut consumption and reduced risk of major chronic diseases and even death, but few prospective cohort studies had examined the link between nut intake and inflammation. In the current study, the research team performed a cross-sectional analysis of data from the Nurses’ Health Study, which includes more than 120,000 female registered nurses, and from the Health Professionals Follow-Up Study, which includes more than 50,000 male health professionals. The team assessed diet using questionnaires and looked at the levels of certain telltale proteins known as biomarkers in blood samples collected from the study participants. They measured three well-established biomarkers of inflammation: C-reactive protein (CRP), interleukin 6 (IL6) and tumor necrosis factor receptor 2 (TNFR2).
After adjusting for age, medical history, lifestyle and other variables, they found that participants who had consumed five or more servings of nuts per week had lower levels of CRP and IL6 than those who never or almost never ate nuts. In addition, people who substituted three servings per week of nuts in place of red meat, processed meat, eggs or refined grains had significantly lower levels of CRP and IL6.
Peanuts and tree nuts contain a number of healthful components including magnesium, fiber, L-arginine, antioxidants and unsaturated fatty acids such as α-linolenic acid. Researchers have not yet determined which of these components, or if the combination of all of them, may offer protection against inflammation, but Bao and her colleagues are interested in exploring this further through clinical trials that would regulate and monitor diet.
“Much remains unknown about how our diet influences inflammation and, in turn, our risk of disease,” said Bao. “But our study supports an overall healthful role for nuts in the diet and suggests reducing inflammation as a potential mechanism that may help explain the benefits of nuts on cardiometabolic diseases.”
Blueberry extract could help fight gum disease and reduce antibiotic use
Laval University (Quebec), September 2, 2022
Gum disease is a common condition among adults that occurs when bacteria form biofilms or plaques on teeth, and consequently the gums become inflamed. Some severe cases, called periodontitis, call for antibiotics. But now scientists have discovered that wild blueberry extract could help prevent dental plaque formation. Their report in ACS’ Journal of Agricultural and Food Chemistry could lead to a new therapy for periodontitis and a reduced need for antibiotics.
Many people have had some degree of gum inflammation, or gingivitis, caused by dental plaque. The gums get red and swollen, and they bleed easily. If left unchecked, the condition can progress to periodontitis. The plaque hardens into tartar, and the infection can spread below the gum line and destroy the tissue supporting the teeth. To treat this condition, dentists scrape off the tartar and sometimes have to resort to conventional antibiotics. But recently, researchers have started looking at natural antibacterial compounds to treat gum disease. Daniel Grenier and colleagues wanted to see if blueberry polyphenols, which work against foodborne pathogens, could also help fight Fusobacterium nucleatum, one of the main species of bacteria associated with periodontitis.
In the lab, the researchers tested extracts from the wild lowbush blueberry, Vaccinium angustifolium Ait., against F. nucleatum. The polyphenol-rich extracts successfully inhibited the growth of F. nucleatum, as well as its ability to form biofilms. It also blocked a molecular pathway involved in inflammation, a key part of gum disease. The researchers say they’re developing an oral device that could slowly release the extract after deep cleaning to help treat periodontitis.
Meat consumption contributing to global obesity
University of Adelaide, August 11, 2022
Should we be warning consumers about over-consumption of meat as well as sugar?
That’s the question being raised by a team of researchers from the University of Adelaide, who say meat in the modern diet offers surplus energy, and is contributing to the prevalence of global obesity.
“Our findings are likely to be controversial because they suggest that meat contributes to obesity prevalence worldwide at the same extent as sugar,” says Professor Maciej Henneberg.
“In the analysis of obesity prevalence across 170 countries, we have found that sugar availability in a nation explains 50% of obesity variation while meat availability another 50%. After correcting for differences in nations’ wealth (Gross Domestic Product), calorie consumption, levels of urbanization and of physical inactivity, which are all major contributors to obesity, sugar availability remained an important factor, contributing independently 13%, while meat contributed another 13% to obesity.
“While we believe it’s important that the public should be alert to the over-consumption of sugar and some fats in their diets, based on our findings we believe meat protein in the human diet is also making a significant contribution to obesity,” Professor Henneberg says.
“There is a dogma that fats and carbohydrates, especially fats, are the major factors contributing to obesity,” Mr You says.
“Whether we like it or not, fats and carbohydrates in modern diets are supplying enough energy to meet our daily needs. Because meat protein is digested later than fats and carbohydrates, this makes the energy we receive from protein a surplus, which is then converted and stored as fat in the human body.”
“Nevertheless, it is important that we show the contribution meat protein is making to obesity so that we can better understand what is happening. In the modern world in which we live, in order to curb obesity it may make sense for dietary guidelines to advise eating less meat, as well as eating less sugar,” he says.
Study suggests possible link between artificial sweeteners and heart diseaseFrench National Institute for Health and Medical Research, September 7, 2022
A large study of French adults published by The BMJ today suggests a potential direct association between higher artificial sweetener consumption and increased cardiovascular disease risk, including heart attack and stroke.
The findings indicate that these food additives, consumed daily by millions of people and present in thousands of foods and drinks, should not be considered a healthy and safe alternative to sugar, in line with the current position of several health agencies.
Artificial sweeteners are widely used as no- or low-calorie alternatives to sugar. They represent a $7.2 billion (£5900m; €7000m) global market and are found in thousands of products worldwide, particularly ultra-processed foods such as artificially sweetened drinks, some snacks, and low calorie ready meals.
Several studies have linked consumption of artificial sweeteners or artificially sweetened beverages (ASB) to weight gain, high blood pressure, and inflammation.
To investigate this further, a team of researchers at the French National Institute for Health and Medical Research (Inserm) and colleagues drew on data for 103,388 participants (average age 42 years; 80% female) of the web-based NutriNet-Santé study, launched in France in 2009 to investigate relations between nutrition and health.
Dietary intakes and consumption of artificial sweeteners were assessed by repeated 24-hour dietary records and a range of potentially influential health, lifestyle, and sociodemographic factors were taken into account.
A total of 37% of participants consumed artificial sweeteners, with an average intake of 42.46 mg/day, which corresponds to approximately one individual packet of table top sweetener or 100 mL of diet soda.
The researchers found that total artificial sweetener intake was associated with an increased risk of cardiovascular disease (absolute rate 346 per 100,000 person years in higher consumers and 314 per 100,000 person years in non-consumers).
Artificial sweeteners were more particularly associated with cerebrovascular disease risk (absolute rates 195 and 150 per 100,000 person-years in higher and non-consumers, respectively).
Aspartame intake was associated with increased risk of cerebrovascular events (186 and 151 per 100,000 person-years in higher and non-consumers, respectively), while acesulfame potassium and sucralose were associated with increased coronary heart disease risk (acesulfame potassium: 167 and 164 per 100,000 person-years; sucralose: 271 and 161 per 100,000 person-years in higher and non-consumers, respectively).
Your soap and toothpaste could be messing with your microbiome
University of Chicago, September 2, 2022
Antimicrobial chemicals found in common household products could be wreaking havoc with people’s guts, according to a research paper out this week in the journal Science.
Triclosan is an antibacterial compound used in soaps, detergent and toothpaste, as well as toys and plastics. It was originally only used in hospitals, but it found its way into homes as Americans became more germ-phobic. (However, recent studies have found it no more effective at killing bacteria than plain soap. )
Now, there are growing concerns about the possible negative effects of the chemical on human health and the environment. According to the US Food and Drug Administration (FDA), animal studies have shown that the chemical can act as a hormone disruptor. A 2008 study found traces of triclosan in the urine of 75% of the participants – some as young as six. The chemical has also been found in more than half of freshwater streams in the US.
Disturbing the human microbiome has been “linked to a wide array of diseases and metabolic disorders, including obesity, inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and behavioral and metabolic disorders,” wrote the paper’s authors, Alyson L Yee and Jack A Gilbert.
Yee and Gilbert also suggested that exposure to triclosan could be even more detrimental to the health of developing fetuses and newborns than to adults. A 2014 New York University study found that gut disruptions in early infancy could have lasting negative effects on immune and brain development.
Triclosan could also be contributing to antibiotic resistance, which scientists believe is caused by the overuse of antimicrobials in humans and animals. There are partial bans of the chemical in the European Union and in Minnesota, and the FDA says it will continue reviewing the chemical for its safety.
Exposure to phthalates could be linked to pregnancy loss
Peking University, September 2, 2022
A new study of more than 300 women suggests that exposure to certain phthalates — substances commonly used in food packaging, personal-care and other everyday products — could be associated with miscarriage, mostly between 5 and 13 weeks of pregnancy. The research, appearing in the ACS journal Environmental Science & Technology, is the first epidemiological study on non-work-related exposure to phthalates to provide evidence for the possible link among a general population.
Out of concern over the potential health effects of phthalates, the U.S. has banned six of these substances from use in certain products made for young children. But many are still included as ingredients in paints, medical tubes, vinyl flooring, soaps, shampoos and other items. Research on phthalates has shown that long-term exposure to low levels of some of these compounds harms lab animals’ health and can increase their risk for pregnancy loss. Additionally, at least one study found that female factory workers exposed to high levels of phthalates through their work were at a higher risk for miscarriage. But there is little epidemiological evidence of phthalates’ effects on pregnancy among women with non-occupational exposure. Jianying Hu, Huan Shen and colleagues wanted to find out if there might be a link.
The researchers tested urine samples from 132 women who had miscarriages and 172 healthy pregnant women in China. They found pregnancy loss was associated with higher levels of urinary phthalate metabolites from diethyl phthalate (DEP), di-isobutyl phthalate (DiBP) and di-n-butyl phthalate (DnBP). Although this doesn’t prove that phthalates cause pregnancy loss, the study suggests an association exists that the researchers say should be studied further.

The Gary Null Show - 09.07.22

VIDEO:
The U.S. secret in Syria EXPOSED in new hidden camera footage | Redacted with Clayton Morris (12:03)
The Conservatives Made Everything in Britain Worse – Johnatan Pie  (6:40)
Neil Oliver: Persuading generations of children they are a plague upon the earth is unforgivable – 12:27
 
Purple potato may pack cancer prevention punch – even after cookingPennsylvania State University, September 1, 2022Anthocyanin compounds found in purple potatoes may help in the prevention of certain types of cancer, even after cooking, say researchers.
The new data, published in the Journal of Nutritional Biochemistry, tested the potential for anthocyanin-containing purple potatoes to block the growth of cancer tumours, even when they have been cooked – after previous research suggested that the polyphenols found in purple potatoes (PP) may help to battle cancer.
Led by Venkata Charepalli from Pennsylvania State University, the team used laboratory tests including in vitro cell line investigations and animal modelling to test how PP impacted colon cancer growth, and in particular, colon cancer stem cells (CSCs), which have previously been suggested to be target by dietary bioactives such as curcumin.
The team reported that their data from in vitro and mouse models suggests that baked purple-fleshed potatoes suppressed the growth of colon cancer tumours by targeting the cancer’s stem cells.
They added that there may be several substances in purple potatoes that work simultaneously, and on multiple pathways, to help kill the colon cancer stem cells, including anthocyanins and chlorogenic acid, and resistant starch.
“Our earlier work and other research studies suggest that potatoes, including purple potatoes, contain resistant starch, which serves as a food for the gut bacteria, that the bacteria can covert to beneficial short-chain fatty acids such as butyric acid,” said study senior author Professor Jairam Vanamal – also of Penn State. “The butyric acid regulates immune function in the gut, suppresses chronic inflammation and may also help to cause cancer cells to self-destruct.”
Boosting physical activity and curbing sitting time are highly likely to lower breast cancer riskBreast Cancer Association Consortium (UK), September 6, 2022Boosting physical activity levels and curbing sitting time are highly likely to lower breast cancer risk, finds research designed to strengthen proof of causation and published online in the British Journal of Sports Medicine.
The findings were generally consistent across all types and stages of the disease, reveals the Mendelian randomization study, prompting the researchers to recommend a stronger focus on exercise as a way of warding off breast cancer.
Mendelian randomization is a technique that uses genetic variants as proxies for a particular risk factor—in this case lifelong physical activity levels/sedentary behavior—to obtain genetic evidence in support of a causal relationship.
Observational studies show that physical inactivity and sedentary behavior are linked to higher breast cancer risk, but proving they cause breast cancer is another matter.
The researchers included data from 130,957 women of European ancestry: 69, 838 of them had tumors that had spread locally (invasive); 6667 had tumors that hadn’t yet done so (in situ); and a comparison group of 54,452 women didn’t have breast cancer.
Researchers estimated overall breast cancer risk, according to whether the women had or hadn’t gone through the menopause; and by cancer type (positive for estrogen or progesterone, or HER-2, or positive/negative for all 3 hormones), stage (size and extent of tumor spread), and grade (degree of tumor cell abnormality).
These case-control groups comprised: 23,999 pre/peri-menopausal women with invasive breast cancer and 17,686 women without; 45,839 postmenopausal women with breast cancer and 36,766 without.
Analysis of the data showed that a higher overall level of genetically predicted physical activity was associated with a 41% lower risk of invasive breast cancer, and this was largely irrespective of menopausal status, tumor type, stage, or grade.
Similarly, genetically predicted vigorous physical activity on 3 or more days of the week was associated with a 38% lower risk of breast cancer, compared with no self-reported vigorous activity. These findings were consistent across most of the case groups.
Finally, a greater level of genetically predicted sitting time was associated with a 104% higher risk of triple negative breast cancer. These findings were consistent across hormone-negative tumor types.
How the mind sharpens the senses
Ruhr University Bochum (Germany), August 27, 2022
A study conducted with experienced scholars of Zen-Meditation shows that mental focussing can induce learning mechanisms, similar to physical training. Researchers at the Ruhr-University Bochum and the Ludwig-Maximilians-University München discovered this phenomenon during a scientifically monitored meditation retreat. The journal Scientific Reports, from the makers of Nature, has now published their new findings on the plasticity of the brain.
The participants were all Zen-scholars with many years of meditation practice. The retreat was held in complete silence, with at least eight hours of meditation per day. All participants practiced their familiar meditation, which is characterized by a non-specific monitoring of thoughts and surroundings. Additionally, some participants applied a special finger-meditation for two hours per day, during which they were asked to specifically focus on their right index finger and become aware of spontaneously arising sensory percepts in this finger. Subsequent assessment of the group that practiced finger-meditation showed a significant improvement in the tactile acuity of the right index and middle finger. A control group that had maintained their familiar meditation practice for the whole time, showed no changes in tactile acuity.
In order to assess the sense of touch quantitatively, researchers measured the so-called “two-point discrimination threshold”. This marker indicates how far apart two stimuli need to be, in order to be discriminated as two separate sensations. After the finger meditation, the performance improved on average by 17 percent. By comparison, tactile acuity of the visually impaired is 15 to 25 percent above that of typical sighted individuals, because their sense of touch is used so intensively to make up for the reduced visual information. Hence, the changes induced by meditation are comparable to those achieved by intense long-term training.
It is known for long that extensive training induces neuroplasticity, which denotes the ability of the brain to adapt and restructure itself, thereby improving perception and behavior. Recently, the group of neuroscientists of the Neural Plasticity Lab headed by Hubert Dinse has shown that these processes can be initiated even without training by mere exposure to passive stimulation, which was translated only recently into a stimulating glove, which is used as therapeutical intervention in stroke patients. The fact that merely mental states without any physical stimulation can improve perception has now been shown for the first time. “The results of our study challenge what we know about learning mechanisms in the brain. Our concept of neuroplasticity must be extended, because mental activity seems to induce learning effects similar to active stimulation and physical training,” Dinse suggests.
Elderberry extract may improve obesity inflammationUniversity of Connecticut , September 1, 2022Black elderberry extract may improve obesity-related metabolic disturbances like triglyceride (TAG) levels, inflammation and insulin resistance, research in mice finds.
The researchers from the University of Connecticut in the US said dietary anthocyanins had been shown to reduce inflammation in animal models and to improve obesity-related complications – and black elderberry (Sambucus nigra) was one of the richest sources of these types of flavonoids.
“Overall, black elderberry extract appeared to attenuate systemic inflammation and insulin resistance that occurs with diet-induced obesity in this mouse model, but further research is warranted on black elderberry consumption and effects in humans,” they wrote in the British Journal of Nutrition.
Mice were fed either a low-fat diet, high-fat lard-based diet, a high-fat diet with 0.25% of the extract or a high-fat with 1.25% of the extract for a period of 16 weeks.
The black elderberry extracts amounted to an anthocyanin dose of 20–40 mg per kg of body weight for the 0.25% group and 100–200 mg for the 1.25% group.
After 16 weeks both extract groups had significantly lower liver weights, serum TAG and serum monocyte chemoattractant protein-1 – a serum marker linked to cardiovascular disease and diabetes – compared to the group given the high fat diet alone.
Liver weights were about 13% lower in both extract groups compared to the group given the high fat diet alone.
“Obese individuals have shortened life expectancies; however, they do not typically die of obesity itself but rather obesity-related comorbidities, such as cardiovascular disease, diabetes and certain types of cancers,” they said.
They said inflammation as a result of adipose fat and excessive accumulation of ectopic lipid in tissues was thought to be a key underlying cause of these obesity-related comorbidities, meaning methods that target and lower inflammation could be effective at preventing obesity-related conditions.
First Ground Breaking Study Shows How Rhodiola Rosea Protects People From Viral Infections
Appalachian State University August 26, 2022
Also known as arctic root or golden root, Rhodiola Rosea has already been clinically shown to stimulate serotonin, norepinephrine and dopamine activity, and support healthy neurotransmitter balance, but human trials have now shown the the herb protects against viral infection.
A 2002 review in HerbalGram, the journal of the American Botanical Council, reported that numerous studies of rhodiola in both humans and animals have indicated that it helps prevent fatigue, stress, and the damaging effects of oxygen deprivation. Evidence also suggests that it acts as an antioxidant, enhances immune system function, and can increase sexual energy. Rhodiola’s efficacy was confirmed in a 2011 review of 11 placebo-controlled human studies. The reviewers considered studies that all had study designs rated as moderate to good quality, and the analysis of their combined data concluded that rhodiola might have beneficial effects on physical performance, mental performance, and certain mental health conditions.
Nieman’s study “Rhodiola rosea exerts antiviral activity in athletes following a competitive marathon race,” which was published July 31 in Frontiers in Nutrition, is the first to show anti-viral activity.
In his study, 48 marathon runners participating in the 2012 Thunder Road Marathon in Charlotte were randomly divided into two groups that ingested either 600 milligrams of Rhodiola rosea or a placebo for a month before the race. Blood samples were collected the day before the marathon and 15 minutes and 1.5 hours post-race. Initial studies found no impact on inflammation and oxidative stress. Additional studies used an in vitro assay to measure the ability of the polyphenolic compounds to protect the cells against Vesicular stomatitis virus. The results demonstrated that Rhodiola rosea delayed viral infection for up to 12 hours after the marathon.
Nieman was the first scientist to find that marathon runners are prone to viral illnesses such as upper respiratory tract infections after competing. This discovery motivated him to research plant-based compounds that could prevent infection and enhance recovery and overall athletic performance.
Since Rhodiola rosea administration appears to impact central monoamine levels, it might also provide benefits and be the adaptogen of choice in clinical conditions characterised by an imbalance of central nervous system monoamines. It also suggests that research in areas such as seasonal affective disorder, fibromyalgia, and chronic fatigue syndrome, among others, is warranted.
“Basically after heavy exertion, bacteria and viruses can multiply at a higher rate than normal due to factors in the serum like stress hormones and inflammatory cytokines,” Nieman said. “This is why runners are six times more likely to get sick after a marathon. We showed that in those who used Rhodiola rosea the viruses could not multiply, meaning it was acting as a countermeasure.”
Rhodiola both stimulates and protects the immune system by reinstating homeostasis (metabolic balance) in the body. It also increases the natural killer cells (NK) in the stomach and spleen. This action may be due to its ability to normalise hormones by modulating the release of glucocorticoid into the body.
How does nature nurture the brain?Max Planck Society, September 6, 2022
After a 60-minute walk in nature, activity in brain regions involved in stress processing decreases. This is the finding of a recent study by the Lise Meitner Group for Environmental Neuroscience at the Max Planck Institute for Human Development, published in Molecular Psychiatry.
Living in a city is a well-known risk factor for developing a mental disorder, while living close to nature is largely beneficial for mental health and the brain. A central brain region involved in stress processing, the amygdala, has been shown to be less activated during stress in people who live in rural areas, compared to those who live in cities, hinting at the potential benefits of nature. “But so far the hen-and-egg problem could not be disentangled, namely whether nature actually caused the effects in the brain or whether the particular individuals chose to live in rural or urban regions,” says Sonja Sudimac, predoctoral fellow in the Lise Meitner Group for Environmental Neuroscience and lead author of the study.
To achieve causal evidence, the researchers from the Lise Meitner Group for Environmental Neuroscience examined brain activity in regions involved in stress processing in 63 healthy volunteers before and after a one-hour walk in Grunewald forest or a shopping street with traffic in Berlin using functional magnetic resonance imaging (fMRI). The results of the study revealed that activity in the amygdala decreased after the walk in nature, suggesting that nature elicits beneficial effects on brain regions related to stress.
“The results support the previously assumed positive relationship between nature and brain health, but this is the first study to prove the causal link. Interestingly, the brain activity after the urban walk in these regions remained stable and did not show increases, which argues against a commonly held view that urban exposure causes additional stress,” explains Simone Kühn, head of the Lise Meitner Group for Environmental Neuroscience.
The authors show that nature has a positive impact on brain regions involved in stress processing and that it can already be observed after a one-hour walk. This contributes to the understanding of how our physical living environment affects brain and mental health. Even a short exposure to nature decreases amygdala activity, suggesting that a walk in nature could serve as a preventive measure against developing mental health problems and buffering the potentially disadvantageous impact of the city on the brain.